File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1111/j.1440-1754.1996.tb00913.x
- Scopus: eid_2-s2.0-0030004199
- PMID: 9156526
- WOS: WOS:A1996UL94400014
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Neurodevelopmental profile of Down syndrome in Chinese children
Title | Neurodevelopmental profile of Down syndrome in Chinese children |
---|---|
Authors | |
Keywords | Developmental quotient Down syndrome Epilepsy Hearing impairment Neurodevelopmental profile Ocular features |
Issue Date | 1996 |
Publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPC |
Citation | Journal Of Paediatrics And Child Health, 1996, v. 32 n. 2, p. 153-157 How to Cite? |
Abstract | Objective: To give an overall appraisal of the clinical features of Down syndrome (DS) in Chinese children with emphasis on the neurodevelopmental outcome, and to compare the related complications with that of other races. Methodology: The records of 124 Chinese children with DS assessed at the Child Assessment Centre of the University Department of Paediatrics in the Duchess of Kent Children's Hospital from 1985 to 1993 were reviewed. Results: Thirty-one per cent of patients had microcephaly. Eighty-five per cent (33/39) when assessed in the first year of life had a developmental quotient (DQ) above 50 but only 29% (2/7) had DQ above 50 when assessed after the age of 5. Only two patients (1.6%) had epilepsy: infantile spasms (1) and Lennox-Gastaut syndrome (1). Hearing impairment was found in 45% of children with mild conductive hearing impairment being the most common. Conclusions: Chinese children with DS, when compared with other races, were similarly intellectually disabled, but were less likely to develop epilepsy. |
Persistent Identifier | http://hdl.handle.net/10722/143589 |
ISSN | 2023 Impact Factor: 1.6 2023 SCImago Journal Rankings: 0.499 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwong, KL | en_HK |
dc.contributor.author | Wong, V | en_HK |
dc.date.accessioned | 2011-12-12T03:52:09Z | - |
dc.date.available | 2011-12-12T03:52:09Z | - |
dc.date.issued | 1996 | en_HK |
dc.identifier.citation | Journal Of Paediatrics And Child Health, 1996, v. 32 n. 2, p. 153-157 | en_HK |
dc.identifier.issn | 1034-4810 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/143589 | - |
dc.description.abstract | Objective: To give an overall appraisal of the clinical features of Down syndrome (DS) in Chinese children with emphasis on the neurodevelopmental outcome, and to compare the related complications with that of other races. Methodology: The records of 124 Chinese children with DS assessed at the Child Assessment Centre of the University Department of Paediatrics in the Duchess of Kent Children's Hospital from 1985 to 1993 were reviewed. Results: Thirty-one per cent of patients had microcephaly. Eighty-five per cent (33/39) when assessed in the first year of life had a developmental quotient (DQ) above 50 but only 29% (2/7) had DQ above 50 when assessed after the age of 5. Only two patients (1.6%) had epilepsy: infantile spasms (1) and Lennox-Gastaut syndrome (1). Hearing impairment was found in 45% of children with mild conductive hearing impairment being the most common. Conclusions: Chinese children with DS, when compared with other races, were similarly intellectually disabled, but were less likely to develop epilepsy. | en_HK |
dc.language | eng | en_US |
dc.publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPC | en_HK |
dc.relation.ispartof | Journal of Paediatrics and Child Health | en_HK |
dc.subject | Developmental quotient | en_HK |
dc.subject | Down syndrome | en_HK |
dc.subject | Epilepsy | en_HK |
dc.subject | Hearing impairment | en_HK |
dc.subject | Neurodevelopmental profile | en_HK |
dc.subject | Ocular features | en_HK |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | *Asian Continental Ancestry Group | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Child, Preschool | en_US |
dc.subject.mesh | China/ethnology | en_US |
dc.subject.mesh | Down Syndrome/*complications/ethnology/genetics | en_US |
dc.subject.mesh | Epilepsy/*etiology | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Hearing Disorders/*etiology | en_US |
dc.subject.mesh | Hong Kong | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Infant | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mental Retardation/*etiology | en_US |
dc.subject.mesh | Microcephaly/*etiology | en_US |
dc.title | Neurodevelopmental profile of Down syndrome in Chinese children | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Wong, V:vcnwong@hku.hk | en_HK |
dc.identifier.authority | Wong, V=rp00334 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/j.1440-1754.1996.tb00913.x | - |
dc.identifier.pmid | 9156526 | - |
dc.identifier.scopus | eid_2-s2.0-0030004199 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0030004199&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 32 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 153 | en_HK |
dc.identifier.epage | 157 | en_HK |
dc.identifier.isi | WOS:A1996UL94400014 | - |
dc.publisher.place | Australia | en_HK |
dc.identifier.scopusauthorid | Kwong, KL=7103035460 | en_HK |
dc.identifier.scopusauthorid | Wong, V=7202525632 | en_HK |
dc.identifier.issnl | 1034-4810 | - |