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Conference Paper: Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity
| Title | Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity |
|---|---|
| Authors | |
| Issue Date | 2011 |
| Citation | The 2011 Meeting of the Days of Molecular Medicine (DMM), Hong Kong, 10-12 November 2011. How to Cite? |
| Abstract | Hirschsprung’s disease (HSCR) is a congenital disease characterized by the absence of ganglian cells in the colon. It would be attributed to the defects in neural differentiation and/or migration of enteric neural crest (NC) cells. For a better understanding of disease pathogenesis of HSCR, our laboratory has recently established two iPS cell lines from a HSCR patient. With a gradient switch from KSR medium to a neural inductive N2 medium supplemented with various neurotropic factors, we could direct human iPS cells to differentiate towards NC cells … |
| Description | DMM 2011 entitled: Re-engineering Regenerative Medicine Poster Session - Neural Regeneration: no. 66 |
| Persistent Identifier | http://hdl.handle.net/10722/144713 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chow, KHM | en_US |
| dc.contributor.author | Yung, JSY | en_US |
| dc.contributor.author | Ngan, ESW | en_US |
| dc.date.accessioned | 2012-02-03T06:19:26Z | - |
| dc.date.available | 2012-02-03T06:19:26Z | - |
| dc.date.issued | 2011 | en_US |
| dc.identifier.citation | The 2011 Meeting of the Days of Molecular Medicine (DMM), Hong Kong, 10-12 November 2011. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/144713 | - |
| dc.description | DMM 2011 entitled: Re-engineering Regenerative Medicine | - |
| dc.description | Poster Session - Neural Regeneration: no. 66 | - |
| dc.description.abstract | Hirschsprung’s disease (HSCR) is a congenital disease characterized by the absence of ganglian cells in the colon. It would be attributed to the defects in neural differentiation and/or migration of enteric neural crest (NC) cells. For a better understanding of disease pathogenesis of HSCR, our laboratory has recently established two iPS cell lines from a HSCR patient. With a gradient switch from KSR medium to a neural inductive N2 medium supplemented with various neurotropic factors, we could direct human iPS cells to differentiate towards NC cells … | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | Day of Molecular Medicine, DMM 2011 | en_US |
| dc.title | Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Chow, KHM: khmchow@hku.hk | en_US |
| dc.identifier.email | Ngan, ESW: engan@hku.hk | en_US |
| dc.identifier.authority | Ngan, ESW=rp00422 | en_US |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 198472 | en_US |