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- Publisher Website: 10.1016/0006-291X(83)91582-6
- Scopus: eid_2-s2.0-0021021390
- PMID: 6661228
- WOS: WOS:A1983RU64100051
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Article: Hemin inhibits transfer of pre-δ-aminolevulinate synthase into chick embryo liver mitochondria
Title | Hemin inhibits transfer of pre-δ-aminolevulinate synthase into chick embryo liver mitochondria |
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Authors | |
Issue Date | 1983 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/description |
Citation | Biochemical And Biophysical Research Communications, 1983, v. 117 n. 1, p. 344-349 How to Cite? |
Abstract | Pulse labelling studies in chick embryo livers show tha hemin prevents the transfer of drug induced pre-δ-aminolevulinate synthase from the cytosol into the mitochondria, leading to an accumulation of precursor in the cytosol. No effect of hemin was observed on the transfer of pre-pyruvate carboxylase into mitochondrial import of proteins and are consistent with the view that hemin specifically inhibits the transfer of ALA synthase. |
Persistent Identifier | http://hdl.handle.net/10722/147737 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.770 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Srivastava, G | en_US |
dc.contributor.author | Borthwick, IA | en_US |
dc.contributor.author | Brooker, JD | en_US |
dc.date.accessioned | 2012-05-29T06:08:59Z | - |
dc.date.available | 2012-05-29T06:08:59Z | - |
dc.date.issued | 1983 | en_US |
dc.identifier.citation | Biochemical And Biophysical Research Communications, 1983, v. 117 n. 1, p. 344-349 | en_US |
dc.identifier.issn | 0006-291X | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/147737 | - |
dc.description.abstract | Pulse labelling studies in chick embryo livers show tha hemin prevents the transfer of drug induced pre-δ-aminolevulinate synthase from the cytosol into the mitochondria, leading to an accumulation of precursor in the cytosol. No effect of hemin was observed on the transfer of pre-pyruvate carboxylase into mitochondrial import of proteins and are consistent with the view that hemin specifically inhibits the transfer of ALA synthase. | en_US |
dc.language | eng | en_US |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/description | en_US |
dc.relation.ispartof | Biochemical and Biophysical Research Communications | en_US |
dc.subject.mesh | 5-Aminolevulinate Synthetase - Genetics | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Chick Embryo | en_US |
dc.subject.mesh | Cytosol - Enzymology | en_US |
dc.subject.mesh | Enzyme Precursors - Genetics | en_US |
dc.subject.mesh | Heme - Pharmacology | en_US |
dc.subject.mesh | Liver - Enzymology | en_US |
dc.subject.mesh | Mitochondria, Liver - Enzymology | en_US |
dc.subject.mesh | Molecular Weight | en_US |
dc.subject.mesh | Protein Processing, Post-Translational - Drug Effects | en_US |
dc.subject.mesh | Pyruvate Carboxylase - Genetics | en_US |
dc.title | Hemin inhibits transfer of pre-δ-aminolevulinate synthase into chick embryo liver mitochondria | en_US |
dc.type | Article | en_US |
dc.identifier.email | Srivastava, G:gopesh@pathology.hku.hk | en_US |
dc.identifier.authority | Srivastava, G=rp00365 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0006-291X(83)91582-6 | - |
dc.identifier.pmid | 6661228 | en_US |
dc.identifier.scopus | eid_2-s2.0-0021021390 | en_US |
dc.identifier.volume | 117 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 344 | en_US |
dc.identifier.epage | 349 | en_US |
dc.identifier.isi | WOS:A1983RU64100051 | - |
dc.publisher.place | United States | en_US |
dc.identifier.issnl | 0006-291X | - |