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Article: Gentamicin nephropathy in a neonate

TitleGentamicin nephropathy in a neonate
Authors
Kwok Wah ChanNg, WL
KeywordsGentamicin nephropathy
Gentamicin toxicity
Neonate
Issue Date1985
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.asp
Citation
Pathology, 1985, v. 17 n. 3, p. 514-515 How to Cite?
DOI: http://dx.doi.org/10.3109/00313028509105512
AbstractThe clinical and autopsy findings in a premature baby who died of acute renal failure after therapy with gentamicin (5 mg/kg/day) and penicillin are presented. The serum gentamicin concentration had reached toxic levels when anuria developed. Numerous periodic acid Schiff (PAS) positive, diastase resistant cytoplasmic inclusion bodies which appeared as myelin figures in cytosegresomes under the electron microscope were identified in the proximal convoluted tubules. The pathological changes induced by gentamicin in the human neonatal kidneys have not been previously reported.
Persistent Identifierhttp://hdl.handle.net/10722/147763
ISSN
0031-3025
2021 Impact Factor: 5.335
2020 SCImago Journal Rankings: 1.335
ISI Accession Number ID
WOS:A1985AMV5200024

 

DC FieldValueLanguage
dc.contributor.authorKwok Wah Chanen_US
dc.contributor.authorNg, WLen_US
dc.date.accessioned2012-05-29T06:09:06Z-
dc.date.available2012-05-29T06:09:06Z-
dc.date.issued1985en_US
dc.identifier.citationPathology, 1985, v. 17 n. 3, p. 514-515en_US
dc.identifier.issn0031-3025en_US
dc.identifier.urihttp://hdl.handle.net/10722/147763-
dc.description.abstractThe clinical and autopsy findings in a premature baby who died of acute renal failure after therapy with gentamicin (5 mg/kg/day) and penicillin are presented. The serum gentamicin concentration had reached toxic levels when anuria developed. Numerous periodic acid Schiff (PAS) positive, diastase resistant cytoplasmic inclusion bodies which appeared as myelin figures in cytosegresomes under the electron microscope were identified in the proximal convoluted tubules. The pathological changes induced by gentamicin in the human neonatal kidneys have not been previously reported.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.aspen_US
dc.relation.ispartofPathologyen_US
dc.subjectGentamicin nephropathy-
dc.subjectGentamicin toxicity-
dc.subjectNeonate-
dc.subject.meshGentamicins - Toxicityen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Newborn, Diseases - Chemically Induceden_US
dc.subject.meshInfant, Prematureen_US
dc.subject.meshKidney Diseases - Chemically Induced - Pathologyen_US
dc.subject.meshKidney Tubules, Proximal - Pathologyen_US
dc.subject.meshMaleen_US
dc.titleGentamicin nephropathy in a neonateen_US
dc.typeArticleen_US
dc.identifier.emailKwok Wah Chan:hrmtckw@hku.hken_US
dc.identifier.authorityKwok Wah Chan=rp00330en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.3109/00313028509105512-
dc.identifier.pmid4069770-
dc.identifier.scopuseid_2-s2.0-0021995421en_US
dc.identifier.volume17en_US
dc.identifier.issue3en_US
dc.identifier.spage514en_US
dc.identifier.epage515en_US
dc.identifier.isiWOS:A1985AMV5200024-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.issnl0031-3025-

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