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Article: Chronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusion

TitleChronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusion
Authors
Wong, KFSo, CCKwong, YL
Issue Date1999
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 1999, v. 115 n. 1, p. 70-72 How to Cite?
DOI: http://dx.doi.org/10.1016/S0165-4608(99)00085-0
AbstractTranslocation (7;11)(p15;p15) is a recently characterized chromosomal abnormality that results in fusion of the NUP98 gene on 11p15 and the HOXA9 gene on 7p15. It shows a strong racial predisposition, being found predominantly in Oriental patients, and has been reported almost exclusively in acute myeloid leukemia, often with associated myelodysplastic changes. In this report, we describe the unique occurrence of t(7;11)(p15;p15) and NUP98/HOXA9 fusion in a patient with chronic myelomonocytic leukemia, and suggest that the genetic lesion may involve multipotential myeloid stem cells. Copyright (C) 1999 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/148171
ISSN
0165-4608
2012 Impact Factor: 1.929
ISI Accession Number ID
WOS:000083564500013
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWong, KFen_HK
dc.contributor.authorSo, CCen_HK
dc.contributor.authorKwong, YLen_HK
dc.date.accessioned2012-05-29T06:11:13Z-
dc.date.available2012-05-29T06:11:13Z-
dc.date.issued1999en_HK
dc.identifier.citationCancer Genetics And Cytogenetics, 1999, v. 115 n. 1, p. 70-72en_HK
dc.identifier.issn0165-4608en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148171-
dc.description.abstractTranslocation (7;11)(p15;p15) is a recently characterized chromosomal abnormality that results in fusion of the NUP98 gene on 11p15 and the HOXA9 gene on 7p15. It shows a strong racial predisposition, being found predominantly in Oriental patients, and has been reported almost exclusively in acute myeloid leukemia, often with associated myelodysplastic changes. In this report, we describe the unique occurrence of t(7;11)(p15;p15) and NUP98/HOXA9 fusion in a patient with chronic myelomonocytic leukemia, and suggest that the genetic lesion may involve multipotential myeloid stem cells. Copyright (C) 1999 Elsevier Science Inc.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_HK
dc.relation.ispartofCancer Genetics and Cytogeneticsen_HK
dc.rightsCancer Genetics and Cytogenetics. Copyright © Elsevier Inc.-
dc.subject.meshAdulten_US
dc.subject.meshChromosomes, Human, Pair 11en_US
dc.subject.meshChromosomes, Human, Pair 7en_US
dc.subject.meshHumansen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshLeukemia, Myelomonocytic, Chronic - Geneticsen_US
dc.subject.meshMaleen_US
dc.subject.meshOncogene Proteins, Fusion - Geneticsen_US
dc.subject.meshReverse Transcriptase Polymerase Chain Reactionen_US
dc.subject.meshTranslocation, Geneticen_US
dc.titleChronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusionen_HK
dc.typeArticleen_HK
dc.identifier.emailSo, CC:scc@pathology.hku.hken_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.authoritySo, CC=rp00391en_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(99)00085-0en_HK
dc.identifier.pmid10565304en_HK
dc.identifier.scopuseid_2-s2.0-0033231320en_HK
dc.identifier.hkuros49586-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033231320&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume115en_HK
dc.identifier.issue1en_HK
dc.identifier.spage70en_HK
dc.identifier.epage72en_HK
dc.identifier.isiWOS:000083564500013-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWong, KF=7404759860en_HK
dc.identifier.scopusauthoridSo, CC=7102919978en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.issnl0165-4608-

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