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Article: Anti-aging herbal medicine-How and why can they be used in aging-associated neurodegenerative diseases?

TitleAnti-aging herbal medicine-How and why can they be used in aging-associated neurodegenerative diseases?
Authors
KeywordsAlzheimer's disease
Ginseng
Neurodegeneration
Parkinson's disease
Wolfberry
Issue Date2010
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/arr
Citation
Ageing Research Reviews, 2010, v. 9 n. 3, p. 354-362 How to Cite?
AbstractAging is a universal biological process that leads to progressive and deleterious changes in organisms. From ancient time, mankind has already interested in preventing and keeping ourselves young. Anti-aging study is certainly not a new research area. Nowadays, the meaning of anti-aging has been changed from simply prolonging lifespan to increasing health span, which emphasizes more on the quality of life. This is the concept of healthy aging and prevention of pathological aging, which is associated with diseases. Keeping our brain functions as in young age is an important task for neuroscientists to prevent aging-associated neurological disorders, such as Alzheimer's diseases (AD) and Parkinson's disease (PD). The causes of these diseases are not fully understood, but it is believed that these diseases are affected by multiple factors. Neurodegenerative diseases can be cross-linked with a number of aging-associated conditions. Based on this, a holistic approach in anti-aging research seems to be more reasonable. Herbal medicine has a long history in Asian countries. It is believed that many of the medicinal herbs have anti-aging properties. Recent studies have shown that some medicinal herbs are effective in intervention or prevention of aging-associated neurological disorders. In this review, we use wolfberry and ginseng as examples to elaborate the properties of anti-aging herbs. The characteristics of medicinal herbs, especially their applications in different disease stages (prevention and intervention) and multi-targets properties, allow them to be potential anti-aging intervention in prevention and treatment of the aging-associated neurological disorders. © 2009 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/149739
ISSN
2023 Impact Factor: 12.5
2023 SCImago Journal Rankings: 3.376
ISI Accession Number ID
Funding AgencyGrant Number
HKU Alzheimer's Disease Research Network
Research Grant Council755206M
761609M
National Science Foundation of China-Research Grant Council of Hong KongN_HKU 707/07M
HKU200811159082
Funding Information:

The work in the Laboratory of Neurodegenerative Diseases is supported by HKU Alzheimer's Disease Research Network under Strategic Research Theme of Healthy Aging, Azalea (1972) Endowment Fund, General Research Fund of Research Grant Council (755206M and 761609M), National Science Foundation of China-Research Grant Council of Hong Kong SAR Joint Research Scheme (N_HKU 707/07M), and HKU Seed Funding for Basic Research (200811159082).

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorHo, YSen_US
dc.contributor.authorSo, KFen_US
dc.contributor.authorChang, RCCen_US
dc.date.accessioned2012-06-26T05:57:50Z-
dc.date.available2012-06-26T05:57:50Z-
dc.date.issued2010en_US
dc.identifier.citationAgeing Research Reviews, 2010, v. 9 n. 3, p. 354-362en_US
dc.identifier.issn1568-1637en_US
dc.identifier.urihttp://hdl.handle.net/10722/149739-
dc.description.abstractAging is a universal biological process that leads to progressive and deleterious changes in organisms. From ancient time, mankind has already interested in preventing and keeping ourselves young. Anti-aging study is certainly not a new research area. Nowadays, the meaning of anti-aging has been changed from simply prolonging lifespan to increasing health span, which emphasizes more on the quality of life. This is the concept of healthy aging and prevention of pathological aging, which is associated with diseases. Keeping our brain functions as in young age is an important task for neuroscientists to prevent aging-associated neurological disorders, such as Alzheimer's diseases (AD) and Parkinson's disease (PD). The causes of these diseases are not fully understood, but it is believed that these diseases are affected by multiple factors. Neurodegenerative diseases can be cross-linked with a number of aging-associated conditions. Based on this, a holistic approach in anti-aging research seems to be more reasonable. Herbal medicine has a long history in Asian countries. It is believed that many of the medicinal herbs have anti-aging properties. Recent studies have shown that some medicinal herbs are effective in intervention or prevention of aging-associated neurological disorders. In this review, we use wolfberry and ginseng as examples to elaborate the properties of anti-aging herbs. The characteristics of medicinal herbs, especially their applications in different disease stages (prevention and intervention) and multi-targets properties, allow them to be potential anti-aging intervention in prevention and treatment of the aging-associated neurological disorders. © 2009 Elsevier Ireland Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/arren_US
dc.relation.ispartofAgeing Research Reviewsen_US
dc.subjectAlzheimer's disease-
dc.subjectGinseng-
dc.subjectNeurodegeneration-
dc.subjectParkinson's disease-
dc.subjectWolfberry-
dc.subject.meshAging - Drug Effectsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDrugs, Chinese Herbal - Pharmacology - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshNeurodegenerative Diseases - Drug Therapy - Prevention & Controlen_US
dc.titleAnti-aging herbal medicine-How and why can they be used in aging-associated neurodegenerative diseases?en_US
dc.typeArticleen_US
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_US
dc.identifier.emailChang, RCC:rccchang@hkucc.hku.hken_US
dc.identifier.authoritySo, KF=rp00329en_US
dc.identifier.authorityChang, RCC=rp00470en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.arr.2009.10.001en_US
dc.identifier.pmid19833234-
dc.identifier.scopuseid_2-s2.0-77952037818en_US
dc.identifier.hkuros170566-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77952037818&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume9en_US
dc.identifier.issue3en_US
dc.identifier.spage354en_US
dc.identifier.epage362en_US
dc.identifier.eissn1872-9649-
dc.identifier.isiWOS:000279094100015-
dc.publisher.placeIrelanden_US
dc.relation.projectImpact of systemic inflammatory responses on the development of Alzheimer pathology-
dc.identifier.scopusauthoridHo, YS=14031513600en_US
dc.identifier.scopusauthoridSo, KF=34668391300en_US
dc.identifier.scopusauthoridChang, RCC=7403713410en_US
dc.identifier.citeulike5976799-
dc.identifier.issnl1568-1637-

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