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- Publisher Website: 10.1093/ije/10.2.161
- Scopus: eid_2-s2.0-0019410892
- PMID: 7287276
- WOS: WOS:A1981MF02400007
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Article: Serum lipids in a teenage population: Geographic, seasonal and familial factors
Title | Serum lipids in a teenage population: Geographic, seasonal and familial factors |
---|---|
Authors | |
Issue Date | 1981 |
Publisher | Oxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/ |
Citation | International Journal Of Epidemiology, 1981, v. 10 n. 2, p. 161-170 How to Cite? |
Abstract | The lipid results of a cross-sectional study of cardiovascular disease risk factors in over 600 13-18 year olds drawn from general practices in contrasting areas are reported. Differences were noted between the 3 practices, including a significant variation in the blood group distribution. HDL cholesterol showed a marked variation between the 3 practices which was unlikely to be due solely to seasonal variation. Alcohol consumption though not a univariate correlate of HDL cholesterol was however a strong partial correlate, as were age, height, sexual maturation, adiposity and smoking. Using 6 factors in each sex, 13% of the interchild variance of HDL cholesterol in boys could be explained in a multiple linear regression analysis, and 8% in girls. Including the practice variation as a further independent variable increased the explanation to 18% in boys and 15% in girls. An intraclass correlation (sib-sib) of 0.36 was found for HDL cholesterol, suggesting a strong familial influence. The implications of these results are discussed, along with the difficulties of screening for hyperlipidaemia in this age group. |
Persistent Identifier | http://hdl.handle.net/10722/151422 |
ISSN | 2023 Impact Factor: 6.4 2023 SCImago Journal Rankings: 2.663 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Orchard, TJ | en_US |
dc.contributor.author | Rodgers, M | en_US |
dc.contributor.author | Hedley, AJ | en_US |
dc.contributor.author | Mitchell, JRA | en_US |
dc.date.accessioned | 2012-06-26T06:23:10Z | - |
dc.date.available | 2012-06-26T06:23:10Z | - |
dc.date.issued | 1981 | en_US |
dc.identifier.citation | International Journal Of Epidemiology, 1981, v. 10 n. 2, p. 161-170 | en_US |
dc.identifier.issn | 0300-5771 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/151422 | - |
dc.description.abstract | The lipid results of a cross-sectional study of cardiovascular disease risk factors in over 600 13-18 year olds drawn from general practices in contrasting areas are reported. Differences were noted between the 3 practices, including a significant variation in the blood group distribution. HDL cholesterol showed a marked variation between the 3 practices which was unlikely to be due solely to seasonal variation. Alcohol consumption though not a univariate correlate of HDL cholesterol was however a strong partial correlate, as were age, height, sexual maturation, adiposity and smoking. Using 6 factors in each sex, 13% of the interchild variance of HDL cholesterol in boys could be explained in a multiple linear regression analysis, and 8% in girls. Including the practice variation as a further independent variable increased the explanation to 18% in boys and 15% in girls. An intraclass correlation (sib-sib) of 0.36 was found for HDL cholesterol, suggesting a strong familial influence. The implications of these results are discussed, along with the difficulties of screening for hyperlipidaemia in this age group. | en_US |
dc.language | eng | en_US |
dc.publisher | Oxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/ | en_US |
dc.relation.ispartof | International Journal of Epidemiology | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Age Factors | en_US |
dc.subject.mesh | Cholesterol - Blood | en_US |
dc.subject.mesh | Cholesterol, Hdl | en_US |
dc.subject.mesh | Diet | en_US |
dc.subject.mesh | England | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Genetics | en_US |
dc.subject.mesh | Growth | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Lipids - Blood | en_US |
dc.subject.mesh | Lipoproteins, Hdl - Blood | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Risk | en_US |
dc.subject.mesh | Seasons | en_US |
dc.subject.mesh | Sex Factors | en_US |
dc.subject.mesh | Sexual Maturation | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Serum lipids in a teenage population: Geographic, seasonal and familial factors | en_US |
dc.type | Article | en_US |
dc.identifier.email | Hedley, AJ:hrmrajh@hkucc.hku.hk | en_US |
dc.identifier.authority | Hedley, AJ=rp00357 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1093/ije/10.2.161 | - |
dc.identifier.pmid | 7287276 | - |
dc.identifier.scopus | eid_2-s2.0-0019410892 | en_US |
dc.identifier.volume | 10 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 161 | en_US |
dc.identifier.epage | 170 | en_US |
dc.identifier.isi | WOS:A1981MF02400007 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Orchard, TJ=7102290820 | en_US |
dc.identifier.scopusauthorid | Rodgers, M=7102573049 | en_US |
dc.identifier.scopusauthorid | Hedley, AJ=7102584095 | en_US |
dc.identifier.scopusauthorid | Mitchell, JRA=24302858200 | en_US |
dc.identifier.issnl | 0300-5771 | - |