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Article: Growth and acid production of Candida species in human saliva supplemented with glucose.

TitleGrowth and acid production of Candida species in human saliva supplemented with glucose.
Authors
Samaranayake, LPHughes, AWeetman, DAMacfarlane, TW
Issue Date1986
Citation
Journal Of Oral Pathology, 1986, v. 15 n. 5, p. 251-254 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1600-0714.1986.tb00617.x
AbstractGrowth characteristic and acid production of oral isolates of Candida albicans and Candida glabrata in glucose supplemented and glucose-free, pooled, human whole saliva were examined. Both Candida species exhibited sigmoidal growth curves in batch cultures of mixed saliva, supplemented with glucose. The growth of Candida in saliva was accompanied by a rapid decline in pH from 7.5 to 3.2 over 48 h and the major acidic components initiating and sustaining this pH drop were pyruvates and acetates. These acidic metabolites may play an important role in the pathogenesis of oral Candida infections.
Persistent Identifierhttp://hdl.handle.net/10722/153591
ISSN
0300-9777
ISI Accession Number ID
WOS:A1986D963400002

 

DC FieldValueLanguage
dc.contributor.authorSamaranayake, LPen_US
dc.contributor.authorHughes, Aen_US
dc.contributor.authorWeetman, DAen_US
dc.contributor.authorMacfarlane, TWen_US
dc.date.accessioned2012-08-08T08:20:32Z-
dc.date.available2012-08-08T08:20:32Z-
dc.date.issued1986en_US
dc.identifier.citationJournal Of Oral Pathology, 1986, v. 15 n. 5, p. 251-254en_US
dc.identifier.issn0300-9777en_US
dc.identifier.urihttp://hdl.handle.net/10722/153591-
dc.description.abstractGrowth characteristic and acid production of oral isolates of Candida albicans and Candida glabrata in glucose supplemented and glucose-free, pooled, human whole saliva were examined. Both Candida species exhibited sigmoidal growth curves in batch cultures of mixed saliva, supplemented with glucose. The growth of Candida in saliva was accompanied by a rapid decline in pH from 7.5 to 3.2 over 48 h and the major acidic components initiating and sustaining this pH drop were pyruvates and acetates. These acidic metabolites may play an important role in the pathogenesis of oral Candida infections.en_US
dc.languageengen_US
dc.relation.ispartofJournal of oral pathologyen_US
dc.subject.meshCandida - Growth & Development - Metabolismen_US
dc.subject.meshCandida Albicans - Growth & Development - Metabolismen_US
dc.subject.meshCarboxylic Acids - Biosynthesisen_US
dc.subject.meshGlucose - Pharmacologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHydrogen-Ion Concentrationen_US
dc.subject.meshSaliva - Metabolism - Microbiology - Physiologyen_US
dc.subject.meshTime Factorsen_US
dc.titleGrowth and acid production of Candida species in human saliva supplemented with glucose.en_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1600-0714.1986.tb00617.x-
dc.identifier.pmid3091791-
dc.identifier.scopuseid_2-s2.0-0022711152en_US
dc.identifier.volume15en_US
dc.identifier.issue5en_US
dc.identifier.spage251en_US
dc.identifier.epage254en_US
dc.identifier.isiWOS:A1986D963400002-
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US
dc.identifier.scopusauthoridHughes, A=7401765766en_US
dc.identifier.scopusauthoridWeetman, DA=7007149532en_US
dc.identifier.scopusauthoridMacFarlane, TW=7005128465en_US
dc.identifier.issnl0300-9777-

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