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Article: Systemic fluconazole therapy and in vitro adhesion of Candida albicans to human buccal epithelial cells

TitleSystemic fluconazole therapy and in vitro adhesion of Candida albicans to human buccal epithelial cells
Authors
Darwazeh, AMGLamey, PJLewis, MAOSamaranayake, LP
Keywordsadhesion
Candida albicans
fluconazole
Issue Date1991
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JOPM
Citation
Journal Of Oral Pathology And Medicine, 1991, v. 20 n. 1, p. 17-19 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1600-0714.1991.tb00881.x
AbstractThe adhesion of Candida albicans to buccal epithelial cells (BEC) from four healthy dentate men was studied in vitro 1 wk before, during and after a course of systemic fluconazole (50 mg once daily for 1 wk). After 1 wk of fluconazole intake candidal adhesion to BEC was significantly reduced and this reduction persisted for a week following completion of therapy. Fluconazole, therefore, in addition to being an effective antifungal agent may also have a sustained action on reducing adherence of candidal species to the oral mucosa.
Persistent Identifierhttp://hdl.handle.net/10722/153740
ISSN
0904-2512
2023 Impact Factor: 2.7
2023 SCImago Journal Rankings: 0.716
ISI Accession Number ID
WOS:A1991EW07400004

 

DC FieldValueLanguage
dc.contributor.authorDarwazeh, AMGen_US
dc.contributor.authorLamey, PJen_US
dc.contributor.authorLewis, MAOen_US
dc.contributor.authorSamaranayake, LPen_US
dc.date.accessioned2012-08-08T08:21:19Z-
dc.date.available2012-08-08T08:21:19Z-
dc.date.issued1991en_US
dc.identifier.citationJournal Of Oral Pathology And Medicine, 1991, v. 20 n. 1, p. 17-19en_US
dc.identifier.issn0904-2512en_US
dc.identifier.urihttp://hdl.handle.net/10722/153740-
dc.description.abstractThe adhesion of Candida albicans to buccal epithelial cells (BEC) from four healthy dentate men was studied in vitro 1 wk before, during and after a course of systemic fluconazole (50 mg once daily for 1 wk). After 1 wk of fluconazole intake candidal adhesion to BEC was significantly reduced and this reduction persisted for a week following completion of therapy. Fluconazole, therefore, in addition to being an effective antifungal agent may also have a sustained action on reducing adherence of candidal species to the oral mucosa.en_US
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JOPMen_US
dc.relation.ispartofJournal of Oral Pathology and Medicineen_US
dc.subjectadhesion-
dc.subjectCandida albicans-
dc.subjectfluconazole-
dc.subject.meshAdulten_US
dc.subject.meshCandida Albicans - Drug Effectsen_US
dc.subject.meshCell Adhesion - Drug Effectsen_US
dc.subject.meshCells, Cultureden_US
dc.subject.meshEpithelial Cellsen_US
dc.subject.meshFluconazole - Pharmacology - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMouth Mucosa - Cytologyen_US
dc.subject.meshTime Factorsen_US
dc.titleSystemic fluconazole therapy and in vitro adhesion of Candida albicans to human buccal epithelial cellsen_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1600-0714.1991.tb00881.xen_US
dc.identifier.pmid2002443-
dc.identifier.scopuseid_2-s2.0-0026067885en_US
dc.identifier.volume20en_US
dc.identifier.issue1en_US
dc.identifier.spage17en_US
dc.identifier.epage19en_US
dc.identifier.isiWOS:A1991EW07400004-
dc.publisher.placeDenmarken_US
dc.identifier.scopusauthoridDarwazeh, AMG=6603911930en_US
dc.identifier.scopusauthoridLamey, PJ=7102581858en_US
dc.identifier.scopusauthoridLewis, MAO=7404189187en_US
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US
dc.identifier.issnl0904-2512-

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