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- Publisher Website: 10.1034/j.1600-0501.1999.100205.x
- Scopus: eid_2-s2.0-0033112622
- PMID: 10219130
- WOS: WOS:000079274100005
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Article: Attempts to obtain re-osseointegration following experimental peri-implantitis in dogs
Title | Attempts to obtain re-osseointegration following experimental peri-implantitis in dogs |
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Authors | |
Keywords | Guided bone regeneration Infection Oral implants Peri-implantitis Reosseointegration Treatment |
Issue Date | 1999 |
Publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR |
Citation | Clinical Oral Implants Research, 1999, v. 10 n. 2, p. 111-119 How to Cite? |
Abstract | The purpose of this study was to examine the healing potential and reosseointegration in peri-implant infection defects adjacent to various implant surfaces. In 7 female Beagle dogs, a total of 41 titanium oral implants (ITI, Straumann, Waldenburg; Switzerland) with a sink depth of 6 mm (diameter 2.8 mm) were placed transmucosally. Four different surface configurations (TPS: titanium plasma sprayed (10); SLA: sand blasted and acid-etched (13); M: machined and smooth (11); TPS furc.: titanium plasma sprayed with coronally placed perforation to mimic a furcation (7) were distributed among the animals and locations. Following a healing period of 3 months, silk ligatures were placed and oral cleaning procedures abolished for 4 months to induce a vertical bone loss of about 40%. Following mechanical and chemical cleansing (chlorhexidine and metronidazole) and disinfection, the lesions were either sham operated (11) or subjected to a GTR procedure using ePTFE (30). After 6 months of healing the animals were killed and the jaws histologically evaluated. Six membranes were lost TPS: (1); SLA: (2); M: (2); TPS furc: (1) and 3 membranes exposed TPS: (1); M: (2) and excluded from further evaluation. Owing to the loss of 1 implant and infection of the membranes in the TPS furc group, this implant configuration was discarded from further analysis. For TPS surfaces, bone fill was 2.6 mm (73% of the distance from the bottom of the defect to the shoulder of the implant) sites with (4 GTR) and 0.33 mm (14%) for sites without membrane (2 controls). Re-osseointegration was 0.5 mm (14%) in the test group and 0.3 mm (14%) in the control. For SLA surfaces bone fill was 2.3 mm (83%) for sites with (7 GTR) and 0.41 mm (15%) for sites without membranes (4 controls). Re-osseointegration was 0.6 mm (20%) and 0.3 mm (11%) respectively. Corresponding values for M surfaces were 2.2 mm (62%) with 4 GTR) and 0.82 mm (31%) without membranes. Re-osseointegration was 0.07 mm (2%) and 0.19 mm (7%) respectively. This study has documented that peri-implant infections defects may heal with bone fill provided that the infection is controlled through effective antibacterial therapy. However, true reosseointegration appears to be difficult to achieve. Copyright © Munksgaard 1999. |
Persistent Identifier | http://hdl.handle.net/10722/154061 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.865 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wetzel, AC | en_US |
dc.contributor.author | Vlassis, J | en_US |
dc.contributor.author | Caffesse, RG | en_US |
dc.contributor.author | Hämmerle, CHF | en_US |
dc.contributor.author | Lang, NP | en_US |
dc.date.accessioned | 2012-08-08T08:23:04Z | - |
dc.date.available | 2012-08-08T08:23:04Z | - |
dc.date.issued | 1999 | en_US |
dc.identifier.citation | Clinical Oral Implants Research, 1999, v. 10 n. 2, p. 111-119 | en_US |
dc.identifier.issn | 0905-7161 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/154061 | - |
dc.description.abstract | The purpose of this study was to examine the healing potential and reosseointegration in peri-implant infection defects adjacent to various implant surfaces. In 7 female Beagle dogs, a total of 41 titanium oral implants (ITI, Straumann, Waldenburg; Switzerland) with a sink depth of 6 mm (diameter 2.8 mm) were placed transmucosally. Four different surface configurations (TPS: titanium plasma sprayed (10); SLA: sand blasted and acid-etched (13); M: machined and smooth (11); TPS furc.: titanium plasma sprayed with coronally placed perforation to mimic a furcation (7) were distributed among the animals and locations. Following a healing period of 3 months, silk ligatures were placed and oral cleaning procedures abolished for 4 months to induce a vertical bone loss of about 40%. Following mechanical and chemical cleansing (chlorhexidine and metronidazole) and disinfection, the lesions were either sham operated (11) or subjected to a GTR procedure using ePTFE (30). After 6 months of healing the animals were killed and the jaws histologically evaluated. Six membranes were lost TPS: (1); SLA: (2); M: (2); TPS furc: (1) and 3 membranes exposed TPS: (1); M: (2) and excluded from further evaluation. Owing to the loss of 1 implant and infection of the membranes in the TPS furc group, this implant configuration was discarded from further analysis. For TPS surfaces, bone fill was 2.6 mm (73% of the distance from the bottom of the defect to the shoulder of the implant) sites with (4 GTR) and 0.33 mm (14%) for sites without membrane (2 controls). Re-osseointegration was 0.5 mm (14%) in the test group and 0.3 mm (14%) in the control. For SLA surfaces bone fill was 2.3 mm (83%) for sites with (7 GTR) and 0.41 mm (15%) for sites without membranes (4 controls). Re-osseointegration was 0.6 mm (20%) and 0.3 mm (11%) respectively. Corresponding values for M surfaces were 2.2 mm (62%) with 4 GTR) and 0.82 mm (31%) without membranes. Re-osseointegration was 0.07 mm (2%) and 0.19 mm (7%) respectively. This study has documented that peri-implant infections defects may heal with bone fill provided that the infection is controlled through effective antibacterial therapy. However, true reosseointegration appears to be difficult to achieve. Copyright © Munksgaard 1999. | en_US |
dc.language | eng | en_US |
dc.publisher | Wiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR | en_US |
dc.relation.ispartof | Clinical Oral Implants Research | en_US |
dc.subject | Guided bone regeneration | - |
dc.subject | Infection | - |
dc.subject | Oral implants | - |
dc.subject | Peri-implantitis | - |
dc.subject | Reosseointegration | - |
dc.subject | Treatment | - |
dc.subject.mesh | Alveolar Process - Physiology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Anti-Infective Agents - Therapeutic Use | en_US |
dc.subject.mesh | Bone Regeneration | en_US |
dc.subject.mesh | Chlorhexidine - Therapeutic Use | en_US |
dc.subject.mesh | Dental Implants - Adverse Effects | en_US |
dc.subject.mesh | Dental Plaque - Complications | en_US |
dc.subject.mesh | Dental Prosthesis Design | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Guided Tissue Regeneration, Periodontal | en_US |
dc.subject.mesh | Membranes, Artificial | en_US |
dc.subject.mesh | Metronidazole - Therapeutic Use | en_US |
dc.subject.mesh | Osseointegration | en_US |
dc.subject.mesh | Periodontitis - Etiology - Therapy | en_US |
dc.subject.mesh | Polytetrafluoroethylene | en_US |
dc.subject.mesh | Prosthesis-Related Infections - Drug Therapy - Etiology | en_US |
dc.subject.mesh | Retreatment | en_US |
dc.subject.mesh | Statistics, Nonparametric | en_US |
dc.subject.mesh | Wound Healing | en_US |
dc.title | Attempts to obtain re-osseointegration following experimental peri-implantitis in dogs | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lang, NP:nplang@hkucc.hku.hk | en_US |
dc.identifier.authority | Lang, NP=rp00031 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1034/j.1600-0501.1999.100205.x | - |
dc.identifier.pmid | 10219130 | - |
dc.identifier.scopus | eid_2-s2.0-0033112622 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033112622&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 10 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 111 | en_US |
dc.identifier.epage | 119 | en_US |
dc.identifier.isi | WOS:000079274100005 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Wetzel, AC=7005517529 | en_US |
dc.identifier.scopusauthorid | Vlassis, J=6603564958 | en_US |
dc.identifier.scopusauthorid | Caffesse, RG=7005708068 | en_US |
dc.identifier.scopusauthorid | Hämmerle, CHF=7005331848 | en_US |
dc.identifier.scopusauthorid | Lang, NP=7201577367 | en_US |
dc.identifier.issnl | 0905-7161 | - |