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Article: In vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida species

TitleIn vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida species
Authors
Meurman, JHKari, KWaltimo, TKotiranta, AInkeri, JSamaranayake, LP
KeywordsAmine fluoride
Antifungal effect
Candida albicans
Candida dubliniensis
Candida glabrata
Candida guilliermondii
Candida krusei
Candida parapsilosis
Candida tropicalis
Stannous fluoride
Issue Date2006
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 2006, v. 12 n. 1, p. 45-50 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1601-0825.2005.01156.x
AbstractOBJECTIVE: The combination of amine fluoride and stannous fluoride (AmF/SnF2) was, by chance, found to be antifungal in a clinical trial. This study investigated its effect on pathogenic Candida species with the hypothesis that the antifungal action on different species is variable. MATERIALS AND METHODS: Growth inhibition effect of Meridol® mouth rinse which contains 250 ppm AmF/SnF2 was evaluated on 43 reference and clinical strains of Candida albicans, C. dubliniensis, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis, and C. tropicalis. Meridol® base solution without AmF/SnF2 was used as a negative control. RESULTS: Undiluted Meridol® mouth rinse killed most study strains within a few minutes. In ascending order, C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, C. krusei and C. dubliniensis showed higher resistance against AmF/SnF2 than C. guilliermondii. CONCLUSION: AmF/SnF2 could be used as a potent adjunct to antifungal therapy for oral yeasts. Although different Candida species demonstrated variable sensitivity the most prevalent oral yeast C. albicans appeared sensitive to the AmF/SnF2 combination. © 2005 Blackwell Munksgaard All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/154390
ISSN
1354-523X
2023 Impact Factor: 2.9
2023 SCImago Journal Rankings: 0.895
ISI Accession Number ID
WOS:000234405300006
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorMeurman, JHen_US
dc.contributor.authorKari, Ken_US
dc.contributor.authorWaltimo, Ten_US
dc.contributor.authorKotiranta, Aen_US
dc.contributor.authorInkeri, Jen_US
dc.contributor.authorSamaranayake, LPen_US
dc.date.accessioned2012-08-08T08:25:03Z-
dc.date.available2012-08-08T08:25:03Z-
dc.date.issued2006en_US
dc.identifier.citationOral Diseases, 2006, v. 12 n. 1, p. 45-50en_US
dc.identifier.issn1354-523Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/154390-
dc.description.abstractOBJECTIVE: The combination of amine fluoride and stannous fluoride (AmF/SnF2) was, by chance, found to be antifungal in a clinical trial. This study investigated its effect on pathogenic Candida species with the hypothesis that the antifungal action on different species is variable. MATERIALS AND METHODS: Growth inhibition effect of Meridol® mouth rinse which contains 250 ppm AmF/SnF2 was evaluated on 43 reference and clinical strains of Candida albicans, C. dubliniensis, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis, and C. tropicalis. Meridol® base solution without AmF/SnF2 was used as a negative control. RESULTS: Undiluted Meridol® mouth rinse killed most study strains within a few minutes. In ascending order, C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, C. krusei and C. dubliniensis showed higher resistance against AmF/SnF2 than C. guilliermondii. CONCLUSION: AmF/SnF2 could be used as a potent adjunct to antifungal therapy for oral yeasts. Although different Candida species demonstrated variable sensitivity the most prevalent oral yeast C. albicans appeared sensitive to the AmF/SnF2 combination. © 2005 Blackwell Munksgaard All rights reserved.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_US
dc.relation.ispartofOral Diseasesen_US
dc.subjectAmine fluoride-
dc.subjectAntifungal effect-
dc.subjectCandida albicans-
dc.subjectCandida dubliniensis-
dc.subjectCandida glabrata-
dc.subjectCandida guilliermondii-
dc.subjectCandida krusei-
dc.subjectCandida parapsilosis-
dc.subjectCandida tropicalis-
dc.subjectStannous fluoride-
dc.subject.meshAmines - Pharmacologyen_US
dc.subject.meshAntifungal Agents - Pharmacologyen_US
dc.subject.meshCandida - Drug Effectsen_US
dc.subject.meshColony Count, Microbialen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshFluorides, Topical - Pharmacologyen_US
dc.subject.meshMouthwashes - Pharmacologyen_US
dc.subject.meshTin Fluorides - Pharmacologyen_US
dc.titleIn vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida speciesen_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1601-0825.2005.01156.xen_US
dc.identifier.pmid16390468-
dc.identifier.scopuseid_2-s2.0-33645027871en_US
dc.identifier.hkuros113071-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645027871&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue1en_US
dc.identifier.spage45en_US
dc.identifier.epage50en_US
dc.identifier.isiWOS:000234405300006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridMeurman, JH=7006469347en_US
dc.identifier.scopusauthoridKari, K=6603526983en_US
dc.identifier.scopusauthoridWaltimo, T=7004089148en_US
dc.identifier.scopusauthoridKotiranta, A=6508273064en_US
dc.identifier.scopusauthoridInkeri, J=12785159100en_US
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US
dc.identifier.citeulike455988-
dc.identifier.issnl1354-523X-

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