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- Publisher Website: 10.1039/c1cc15317j
- Scopus: eid_2-s2.0-82555193685
- PMID: 22085845
- WOS: WOS:000297559200015
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Article: Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes
Title | Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes |
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Authors | |
Issue Date | 2012 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp |
Citation | Chemical Communications, 2012, v. 48 n. 2, p. 230-232 How to Cite? |
Abstract | Cyclometalated platinum(II) complexes [Pt(II)(C^N^N)(C identical withNR)](+) (HC^N^N = 6-phenyl-2,2'-bipyridyl) display significant inhibition towards TNF-alpha stimulated NF-kappaB-dependent gene transcription at concentrations down to the micromolar range. |
Persistent Identifier | http://hdl.handle.net/10722/159397 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.133 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, J | en_HK |
dc.contributor.author | Sun, RWY | en_HK |
dc.contributor.author | Leung, CH | en_HK |
dc.contributor.author | Lok, CN | en_HK |
dc.contributor.author | Che, CM | en_HK |
dc.date.accessioned | 2012-08-16T05:49:05Z | - |
dc.date.available | 2012-08-16T05:49:05Z | - |
dc.date.issued | 2012 | en_HK |
dc.identifier.citation | Chemical Communications, 2012, v. 48 n. 2, p. 230-232 | en_HK |
dc.identifier.issn | 1359-7345 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/159397 | - |
dc.description.abstract | Cyclometalated platinum(II) complexes [Pt(II)(C^N^N)(C identical withNR)](+) (HC^N^N = 6-phenyl-2,2'-bipyridyl) display significant inhibition towards TNF-alpha stimulated NF-kappaB-dependent gene transcription at concentrations down to the micromolar range. | en_HK |
dc.language | eng | en_US |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | en_HK |
dc.relation.ispartof | Chemical Communications | en_HK |
dc.subject.mesh | Antineoplastic Agents - chemistry - pharmacology | en_HK |
dc.subject.mesh | Gene Expression Regulation, Neoplastic - drug effects | en_HK |
dc.subject.mesh | NF-kappa B - immunology - metabolism | en_HK |
dc.subject.mesh | Platinum Compounds - chemistry - pharmacology | en_HK |
dc.subject.mesh | Tumor Necrosis Factor-alpha - immunology - metabolism | en_HK |
dc.title | Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Liu, J: juliaga@hku.hk | en_HK |
dc.identifier.email | Sun, RWY: rwysun@hku.hk | en_HK |
dc.identifier.email | Leung, CH: duncanl@hkucc.hku.hk | en_HK |
dc.identifier.email | Lok, CN: cnlok@hku.hk | en_HK |
dc.identifier.email | Che, CM: cmche@hku.hk | - |
dc.identifier.authority | Sun, RWY=rp00781 | en_HK |
dc.identifier.authority | Leung, CH=rp00730 | en_HK |
dc.identifier.authority | Lok, CN=rp00752 | en_HK |
dc.identifier.authority | Che, CM=rp00670 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1039/c1cc15317j | en_HK |
dc.identifier.pmid | 22085845 | - |
dc.identifier.scopus | eid_2-s2.0-82555193685 | en_HK |
dc.identifier.hkuros | 205259 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-82555193685&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 48 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 230 | en_HK |
dc.identifier.epage | 232 | en_HK |
dc.identifier.eissn | 1364-548X | - |
dc.identifier.isi | WOS:000297559200015 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Che, CM=7102442791 | en_HK |
dc.identifier.scopusauthorid | Lok, CN=7006410829 | en_HK |
dc.identifier.scopusauthorid | Leung, CH=7402612570 | en_HK |
dc.identifier.scopusauthorid | Sun, RWY=26325835800 | en_HK |
dc.identifier.scopusauthorid | Liu, J=37122146100 | en_HK |
dc.identifier.issnl | 1359-7345 | - |