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Article: Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes

TitleInhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes
Authors
Liu, JSun, RWYLeung, CHLok, CNChe, CM
Issue Date2012
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2012, v. 48 n. 2, p. 230-232 How to Cite?
DOI: http://dx.doi.org/10.1039/c1cc15317j
AbstractCyclometalated platinum(II) complexes [Pt(II)(C^N^N)(C identical withNR)](+) (HC^N^N = 6-phenyl-2,2'-bipyridyl) display significant inhibition towards TNF-alpha stimulated NF-kappaB-dependent gene transcription at concentrations down to the micromolar range.
Persistent Identifierhttp://hdl.handle.net/10722/159397
ISSN
1359-7345
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.133
ISI Accession Number ID
WOS:000297559200015
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLiu, Jen_HK
dc.contributor.authorSun, RWYen_HK
dc.contributor.authorLeung, CHen_HK
dc.contributor.authorLok, CNen_HK
dc.contributor.authorChe, CMen_HK
dc.date.accessioned2012-08-16T05:49:05Z-
dc.date.available2012-08-16T05:49:05Z-
dc.date.issued2012en_HK
dc.identifier.citationChemical Communications, 2012, v. 48 n. 2, p. 230-232en_HK
dc.identifier.issn1359-7345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/159397-
dc.description.abstractCyclometalated platinum(II) complexes [Pt(II)(C^N^N)(C identical withNR)](+) (HC^N^N = 6-phenyl-2,2'-bipyridyl) display significant inhibition towards TNF-alpha stimulated NF-kappaB-dependent gene transcription at concentrations down to the micromolar range.en_HK
dc.languageengen_US
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.aspen_HK
dc.relation.ispartofChemical Communicationsen_HK
dc.subject.meshAntineoplastic Agents - chemistry - pharmacologyen_HK
dc.subject.meshGene Expression Regulation, Neoplastic - drug effectsen_HK
dc.subject.meshNF-kappa B - immunology - metabolismen_HK
dc.subject.meshPlatinum Compounds - chemistry - pharmacologyen_HK
dc.subject.meshTumor Necrosis Factor-alpha - immunology - metabolismen_HK
dc.titleInhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexesen_HK
dc.typeArticleen_HK
dc.identifier.emailLiu, J: juliaga@hku.hken_HK
dc.identifier.emailSun, RWY: rwysun@hku.hken_HK
dc.identifier.emailLeung, CH: duncanl@hkucc.hku.hken_HK
dc.identifier.emailLok, CN: cnlok@hku.hken_HK
dc.identifier.emailChe, CM: cmche@hku.hk-
dc.identifier.authoritySun, RWY=rp00781en_HK
dc.identifier.authorityLeung, CH=rp00730en_HK
dc.identifier.authorityLok, CN=rp00752en_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/c1cc15317jen_HK
dc.identifier.pmid22085845-
dc.identifier.scopuseid_2-s2.0-82555193685en_HK
dc.identifier.hkuros205259en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-82555193685&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume48en_HK
dc.identifier.issue2en_HK
dc.identifier.spage230en_HK
dc.identifier.epage232en_HK
dc.identifier.eissn1364-548X-
dc.identifier.isiWOS:000297559200015-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK
dc.identifier.scopusauthoridLok, CN=7006410829en_HK
dc.identifier.scopusauthoridLeung, CH=7402612570en_HK
dc.identifier.scopusauthoridSun, RWY=26325835800en_HK
dc.identifier.scopusauthoridLiu, J=37122146100en_HK
dc.identifier.issnl1359-7345-

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