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Article: Preparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNA

TitlePreparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNA
Authors
KeywordsDNA
Emulsifier-free emulsion polymerization
Fluorescence spectroscopy
Magnetic polymer
Polycations
Issue Date2012
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jmmm
Citation
Journal Of Magnetism And Magnetic Materials, 2012, v. 324 n. 7, p. 1410-1418 How to Cite?
AbstractCationic magnetic polymer particles Fe 3O 4/ poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride), a type of potential gene carrier, were prepared by emulsifier-free emulsion polymerization with oleic acid modified magnetite Fe 3O 4, styrene, butyl acrylate and [2-(methacryloxy)ethyl]trimethylammonium chloride) (METAC). The morphology of the particles was characterized by transmission electron microscopy and the composites of particles were characterized by FT-IR spectroscopy, X-ray diffraction. These results showed that magnetic particles were well dispersed in polymers with the content of about 15%(wt/wt). The composites exhibited superparamagnetism and possessed a certain level of magnetic response. The interactions between the particles with calf-thymus DNA (ct DNA) were confirmed by zeta potential measurement, UVvis spectroscopy and fluorescence spectroscopy. The DNA-binding capacity determined by the agarose gel electrophoresis showed good binding capacity of the emulsion to DNA. These results suggested the potential of the cationic magnetic polymer emulsion as gene target delivery carrier. © 2011 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/159756
ISSN
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.522
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLi, Xen_HK
dc.contributor.authorLiu, Gen_HK
dc.contributor.authorYan, Wen_HK
dc.contributor.authorChu, PKen_HK
dc.contributor.authorYeung, KWKen_HK
dc.contributor.authorWu, Sen_HK
dc.contributor.authorYi, Cen_HK
dc.contributor.authorXu, Zen_HK
dc.date.accessioned2012-08-16T05:55:35Z-
dc.date.available2012-08-16T05:55:35Z-
dc.date.issued2012en_HK
dc.identifier.citationJournal Of Magnetism And Magnetic Materials, 2012, v. 324 n. 7, p. 1410-1418en_HK
dc.identifier.issn0304-8853en_HK
dc.identifier.urihttp://hdl.handle.net/10722/159756-
dc.description.abstractCationic magnetic polymer particles Fe 3O 4/ poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride), a type of potential gene carrier, were prepared by emulsifier-free emulsion polymerization with oleic acid modified magnetite Fe 3O 4, styrene, butyl acrylate and [2-(methacryloxy)ethyl]trimethylammonium chloride) (METAC). The morphology of the particles was characterized by transmission electron microscopy and the composites of particles were characterized by FT-IR spectroscopy, X-ray diffraction. These results showed that magnetic particles were well dispersed in polymers with the content of about 15%(wt/wt). The composites exhibited superparamagnetism and possessed a certain level of magnetic response. The interactions between the particles with calf-thymus DNA (ct DNA) were confirmed by zeta potential measurement, UVvis spectroscopy and fluorescence spectroscopy. The DNA-binding capacity determined by the agarose gel electrophoresis showed good binding capacity of the emulsion to DNA. These results suggested the potential of the cationic magnetic polymer emulsion as gene target delivery carrier. © 2011 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jmmmen_HK
dc.relation.ispartofJournal of Magnetism and Magnetic Materialsen_HK
dc.subjectDNAen_HK
dc.subjectEmulsifier-free emulsion polymerizationen_HK
dc.subjectFluorescence spectroscopyen_HK
dc.subjectMagnetic polymeren_HK
dc.subjectPolycationsen_HK
dc.titlePreparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNAen_HK
dc.typeArticleen_HK
dc.identifier.emailYeung, KWK:wkkyeung@hkucc.hku.hken_HK
dc.identifier.authorityYeung, KWK=rp00309en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jmmm.2011.11.056en_HK
dc.identifier.scopuseid_2-s2.0-84855440269en_HK
dc.identifier.hkuros204535en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84855440269&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume324en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1410en_HK
dc.identifier.epage1418en_HK
dc.identifier.isiWOS:000299010100026-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLi, X=54684373400en_HK
dc.identifier.scopusauthoridLiu, G=54684435700en_HK
dc.identifier.scopusauthoridYan, W=39262757600en_HK
dc.identifier.scopusauthoridChu, PK=36040705700en_HK
dc.identifier.scopusauthoridYeung, KWK=13309584700en_HK
dc.identifier.scopusauthoridWu, S=15125218800en_HK
dc.identifier.scopusauthoridYi, C=7101997365en_HK
dc.identifier.scopusauthoridXu, Z=12760201200en_HK
dc.identifier.citeulike10135398-
dc.identifier.issnl0304-8853-

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