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Conference Paper: Effects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat heart
| Title | Effects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat heart |
|---|---|
| Authors | |
| Keywords | Medical sciences Respiratory diseases |
| Issue Date | 2012 |
| Publisher | American Thoracic Society. The Conference Abstracts' web site is located at http://www.atsjournals.org/series/ajrccm-conference |
| Citation | The 2012 International Conference of the American Thoracic Society, San Francisco, CA., 18-23 May 2012. In American Journal of Respiratory and Critical Care Medicine, 2012, v. 185 meeting abstracts, abstract A3869 How to Cite? |
| Abstract | RATIONALE: Fatty acid-binding proteins (FABPs) are members of the lipid-binding proteins (LBPs) superfamily, regulating the fatty acid uptake and intercellular transport. Among 9 subtypes identified with tissue-specific distribution, serum A- and H-FABP have been found to be significantly higher in patients with obstructive sleep apnea (OSA) than in controls (Sleep Breath 2008;12:223-228; Eur Respir J 2009;33:346-351). Intermittent hypoxia (IH) is a hallmark feature in OSA, which is increasingly recognized as an independent risk factor of cardiovascular diseases (CVD). In this study, we hypothesized that IH could regulate both lipid parameters and the expression of specific ABPs leading to heart damage. We aimed to study systemic and cardiac lipid parameters and the specific expression of cardiac FABPs. METHODS: Male Sprague–Dawley rats … |
| Description | Session B109 Sleep Disordered Breathing and Cardiovascular Disease: Of Rodents and Humans Poster Discussion Session Open Access Journal |
| Persistent Identifier | http://hdl.handle.net/10722/160340 |
| ISSN | 2021 Impact Factor: 30.528 2020 SCImago Journal Rankings: 6.272 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mak, JCW | en_US |
| dc.contributor.author | Han, Q | en_US |
| dc.contributor.author | Yeung, SC | en_US |
| dc.contributor.author | Ip, MSM | en_US |
| dc.date.accessioned | 2012-08-16T06:08:07Z | - |
| dc.date.available | 2012-08-16T06:08:07Z | - |
| dc.date.issued | 2012 | en_US |
| dc.identifier.citation | The 2012 International Conference of the American Thoracic Society, San Francisco, CA., 18-23 May 2012. In American Journal of Respiratory and Critical Care Medicine, 2012, v. 185 meeting abstracts, abstract A3869 | en_US |
| dc.identifier.issn | 1073-449X | - |
| dc.identifier.uri | http://hdl.handle.net/10722/160340 | - |
| dc.description | Session B109 Sleep Disordered Breathing and Cardiovascular Disease: Of Rodents and Humans | - |
| dc.description | Poster Discussion Session | - |
| dc.description | Open Access Journal | - |
| dc.description.abstract | RATIONALE: Fatty acid-binding proteins (FABPs) are members of the lipid-binding proteins (LBPs) superfamily, regulating the fatty acid uptake and intercellular transport. Among 9 subtypes identified with tissue-specific distribution, serum A- and H-FABP have been found to be significantly higher in patients with obstructive sleep apnea (OSA) than in controls (Sleep Breath 2008;12:223-228; Eur Respir J 2009;33:346-351). Intermittent hypoxia (IH) is a hallmark feature in OSA, which is increasingly recognized as an independent risk factor of cardiovascular diseases (CVD). In this study, we hypothesized that IH could regulate both lipid parameters and the expression of specific ABPs leading to heart damage. We aimed to study systemic and cardiac lipid parameters and the specific expression of cardiac FABPs. METHODS: Male Sprague–Dawley rats … | - |
| dc.language | eng | en_US |
| dc.publisher | American Thoracic Society. The Conference Abstracts' web site is located at http://www.atsjournals.org/series/ajrccm-conference | - |
| dc.relation.ispartof | American Journal of Respiratory and Critical Care Medicine | en_US |
| dc.subject | Medical sciences | - |
| dc.subject | Respiratory diseases | - |
| dc.title | Effects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat heart | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Mak, JCW: judymak@hku.hk | en_US |
| dc.identifier.email | Yeung, SC: flag@hkucc.hku.hk | en_US |
| dc.identifier.email | Ip, MSM: msmip@hku.hk | en_US |
| dc.identifier.authority | Mak, JCW=rp00352 | en_US |
| dc.identifier.authority | Ip, MSM=rp00347 | en_US |
| dc.description.nature | link_to_OA_fulltext | - |
| dc.identifier.doi | 10.1164/ajrccm-conference.2012.185.1_MeetingAbstracts.A3869 | - |
| dc.identifier.hkuros | 204434 | en_US |
| dc.identifier.volume | 185 | en_US |
| dc.identifier.issue | meeting abstracts | - |
| dc.publisher.place | United States | - |
| dc.customcontrol.immutable | sml 140123 | - |
| dc.identifier.issnl | 1073-449X | - |