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Article: Management of tetanus: A review of 18 cases

TitleManagement of tetanus: A review of 18 cases
Authors
Issue Date1994
PublisherRoyal Society of Medicine Press Ltd. The Journal's web site is located at http://www.roysocmed.ac.uk/pub/jrsm.htm
Citation
Journal Of The Royal Society Of Medicine, 1994, v. 87 n. 3, p. 135-137 How to Cite?
AbstractEighteen patients with generalized tetanus seen during an 8-year period in three regional hospitals in Hong Kong are reviewed. Eighty-nine per cent of the patients were intravenous heroin addicts who developed a severe type of generalized tetanus with autonomic dysfunction. Pain or stiffness of the neck or back was the commonest presenting symptom, followed by trismus and dysphagia. Most of the patients developed muscle spasms within 24 h of the onset of presenting symptoms. Early ventilatory support and tracheostomy, together with intensive nursing care, were the mainstay of the treatment. Pulmonary and gastrointestinal complications were common during the course of illness and treatment of autonomic dysfunction was often unsatisfactory. The case fatality rate was 25% among the heroin addicts, but full recovery was the usual outcome for those who survived. The simultaneous administration of intrathecal tetanus immunoglobulin tends to reduce mortality.
Persistent Identifierhttp://hdl.handle.net/10722/162043
ISSN
2023 Impact Factor: 8.8
2023 SCImago Journal Rankings: 1.524
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSun, KOen_US
dc.contributor.authorChan, YWen_US
dc.contributor.authorCheung, RTFen_US
dc.contributor.authorSo, PCen_US
dc.contributor.authorYu, YLen_US
dc.contributor.authorLi, PCKen_US
dc.date.accessioned2012-09-05T05:16:52Z-
dc.date.available2012-09-05T05:16:52Z-
dc.date.issued1994en_US
dc.identifier.citationJournal Of The Royal Society Of Medicine, 1994, v. 87 n. 3, p. 135-137en_US
dc.identifier.issn0141-0768en_US
dc.identifier.urihttp://hdl.handle.net/10722/162043-
dc.description.abstractEighteen patients with generalized tetanus seen during an 8-year period in three regional hospitals in Hong Kong are reviewed. Eighty-nine per cent of the patients were intravenous heroin addicts who developed a severe type of generalized tetanus with autonomic dysfunction. Pain or stiffness of the neck or back was the commonest presenting symptom, followed by trismus and dysphagia. Most of the patients developed muscle spasms within 24 h of the onset of presenting symptoms. Early ventilatory support and tracheostomy, together with intensive nursing care, were the mainstay of the treatment. Pulmonary and gastrointestinal complications were common during the course of illness and treatment of autonomic dysfunction was often unsatisfactory. The case fatality rate was 25% among the heroin addicts, but full recovery was the usual outcome for those who survived. The simultaneous administration of intrathecal tetanus immunoglobulin tends to reduce mortality.en_US
dc.languageengen_US
dc.publisherRoyal Society of Medicine Press Ltd. The Journal's web site is located at http://www.roysocmed.ac.uk/pub/jrsm.htmen_US
dc.relation.ispartofJournal of the Royal Society of Medicineen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAutonomic Nervous System Diseases - Etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeroin Dependence - Complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulins - Therapeutic Useen_US
dc.subject.meshInjections, Spinalen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSubstance Abuse, Intravenous - Complicationsen_US
dc.subject.meshTetanus - Complications - Diagnosis - Therapyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleManagement of tetanus: A review of 18 casesen_US
dc.typeArticleen_US
dc.identifier.emailCheung, RTF:rtcheung@hku.hken_US
dc.identifier.authorityCheung, RTF=rp00434en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8158589-
dc.identifier.scopuseid_2-s2.0-0028202754en_US
dc.identifier.volume87en_US
dc.identifier.issue3en_US
dc.identifier.spage135en_US
dc.identifier.epage137en_US
dc.identifier.isiWOS:A1994MZ74900006-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridSun, KO=7401518554en_US
dc.identifier.scopusauthoridChan, YW=7403676058en_US
dc.identifier.scopusauthoridCheung, RTF=7202397498en_US
dc.identifier.scopusauthoridSo, PC=7102823666en_US
dc.identifier.scopusauthoridYu, YL=8094845300en_US
dc.identifier.scopusauthoridLi, PCK=36068280500en_US
dc.identifier.issnl0141-0768-

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