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- Publisher Website: 10.1002/(SICI)1096-8652(199912)62:4<256::AID-AJH12>3.0.CO;2-B
- Scopus: eid_2-s2.0-0032735921
- PMID: 10589085
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Article: Isolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatment
Title | Isolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatment |
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Authors | |
Keywords | Chronic myeloid leukemia T lymphoblastic lymphoma |
Issue Date | 1999 |
Publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105 |
Citation | American Journal Of Hematology, 1999, v. 62 n. 4, p. 256-258 How to Cite? |
Abstract | Isolated nodal T lymphoblastic transformation of chronic myeloid leukemia (CML) with the marrow still in chronic phase is rare. A case of CML treated by α-interferon developed this unusual complication. However, after successful treatment of the blastic transformation, the patient remained responsive to interferon and maintained a major cytogenetic response for over 2 years. This case illustrated a rare clinical progression of CML on interferon treatment to isolated nodal T lymphoblastic transformation. This unusual form of blastic transformation may have a better prognosis than other forms of blastic crisis. |
Persistent Identifier | http://hdl.handle.net/10722/162287 |
ISSN | 2023 Impact Factor: 10.1 2023 SCImago Journal Rankings: 2.607 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Au, WY | en_US |
dc.contributor.author | Chan, ACL | en_US |
dc.contributor.author | Kwong, YL | en_US |
dc.date.accessioned | 2012-09-05T05:18:41Z | - |
dc.date.available | 2012-09-05T05:18:41Z | - |
dc.date.issued | 1999 | en_US |
dc.identifier.citation | American Journal Of Hematology, 1999, v. 62 n. 4, p. 256-258 | en_US |
dc.identifier.issn | 0361-8609 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/162287 | - |
dc.description.abstract | Isolated nodal T lymphoblastic transformation of chronic myeloid leukemia (CML) with the marrow still in chronic phase is rare. A case of CML treated by α-interferon developed this unusual complication. However, after successful treatment of the blastic transformation, the patient remained responsive to interferon and maintained a major cytogenetic response for over 2 years. This case illustrated a rare clinical progression of CML on interferon treatment to isolated nodal T lymphoblastic transformation. This unusual form of blastic transformation may have a better prognosis than other forms of blastic crisis. | en_US |
dc.language | eng | en_US |
dc.publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105 | en_US |
dc.relation.ispartof | American Journal of Hematology | en_US |
dc.rights | American Journal of Hematology. Copyright © John Wiley & Sons, Inc. | - |
dc.subject | Chronic myeloid leukemia | - |
dc.subject | T lymphoblastic lymphoma | - |
dc.subject.mesh | Antineoplastic Combined Chemotherapy Protocols - Therapeutic Use | en_US |
dc.subject.mesh | Bone Marrow - Pathology | en_US |
dc.subject.mesh | Chromosomes, Human, Pair 22 | en_US |
dc.subject.mesh | Chromosomes, Human, Pair 9 | en_US |
dc.subject.mesh | Fusion Proteins, Bcr-Abl - Genetics | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Immunophenotyping | en_US |
dc.subject.mesh | In Situ Hybridization, Fluorescence | en_US |
dc.subject.mesh | Interferon-Alpha - Therapeutic Use | en_US |
dc.subject.mesh | Leukemia, Myelogenous, Chronic, Bcr-Abl Positive - Genetics - Pathology - Therapy | en_US |
dc.subject.mesh | Lymph Nodes - Pathology | en_US |
dc.subject.mesh | Lymphocyte Activation | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Remission Induction | en_US |
dc.subject.mesh | T-Lymphocytes - Pathology | en_US |
dc.subject.mesh | Translocation, Genetic | en_US |
dc.title | Isolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatment | en_US |
dc.type | Article | en_US |
dc.identifier.email | Kwong, YL:ylkwong@hku.hk | en_US |
dc.identifier.authority | Kwong, YL=rp00358 | en_US |
dc.description.nature | link_to_OA_fulltext | en_US |
dc.identifier.doi | 10.1002/(SICI)1096-8652(199912)62:4<256::AID-AJH12>3.0.CO;2-B | en_US |
dc.identifier.pmid | 10589085 | - |
dc.identifier.scopus | eid_2-s2.0-0032735921 | en_US |
dc.identifier.hkuros | 49590 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032735921&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 62 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 256 | en_US |
dc.identifier.epage | 258 | en_US |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Au, WY=7202383089 | en_US |
dc.identifier.scopusauthorid | Chan, ACL=16047349300 | en_US |
dc.identifier.scopusauthorid | Kwong, YL=7102818954 | en_US |
dc.identifier.issnl | 0361-8609 | - |