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Article: Eosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)

TitleEosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)
Authors
Chim, CSMa, SK
KeywordsEosinophilic leukemia
Hydroxyurea
Polycythemia vera
Issue Date2005
PublisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lal
Citation
Leukemia And Lymphoma, 2005, v. 46 n. 3, p. 447-450 How to Cite?
DOI: http://dx.doi.org/10.1080/10428190400007649
AbstractWe report a rare case of eosinophilic leukemia transformation in a patient with polycythemia rubra vera on hydroxycarbamide (hydroxyurea) therapy only. Cytogenetic study showed complex abnormalities including -5, -7, +8, suggestive of a secondary leukemia. The leukemogenic risk of hydroxycarbamide, a ribonucleoside reductase, and the risk of natural leukemic transformation of polycythemia rubra vera is discussed in the context of previous PVSG studies. © 2005 Taylor & Francis Group Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/162788
ISSN
1042-8194
2023 Impact Factor: 2.2
2023 SCImago Journal Rankings: 0.790
ISI Accession Number ID
WOS:000225878000018
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorChim, CSen_US
dc.contributor.authorMa, SKen_US
dc.date.accessioned2012-09-05T05:23:32Z-
dc.date.available2012-09-05T05:23:32Z-
dc.date.issued2005en_US
dc.identifier.citationLeukemia And Lymphoma, 2005, v. 46 n. 3, p. 447-450en_US
dc.identifier.issn1042-8194en_US
dc.identifier.urihttp://hdl.handle.net/10722/162788-
dc.description.abstractWe report a rare case of eosinophilic leukemia transformation in a patient with polycythemia rubra vera on hydroxycarbamide (hydroxyurea) therapy only. Cytogenetic study showed complex abnormalities including -5, -7, +8, suggestive of a secondary leukemia. The leukemogenic risk of hydroxycarbamide, a ribonucleoside reductase, and the risk of natural leukemic transformation of polycythemia rubra vera is discussed in the context of previous PVSG studies. © 2005 Taylor & Francis Group Ltd.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lalen_US
dc.relation.ispartofLeukemia and Lymphomaen_US
dc.rightsLeukemia and Lymphoma. Copyright © Informa Healthcare.-
dc.subjectEosinophilic leukemia-
dc.subjectHydroxyurea-
dc.subjectPolycythemia vera-
dc.subject.meshAgeden_US
dc.subject.meshChromosome Aberrationsen_US
dc.subject.meshCytogenetic Analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshHydroxyurea - Therapeutic Useen_US
dc.subject.meshHypereosinophilic Syndrome - Complications - Drug Therapy - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPolycythemia Vera - Complications - Drug Therapyen_US
dc.titleEosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)en_US
dc.typeArticleen_US
dc.identifier.emailChim, CS:jcschim@hku.hken_US
dc.identifier.authorityChim, CS=rp00408en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1080/10428190400007649en_US
dc.identifier.pmid15621837en_US
dc.identifier.scopuseid_2-s2.0-13544272027en_US
dc.identifier.hkuros99021-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-13544272027&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume46en_US
dc.identifier.issue3en_US
dc.identifier.spage447en_US
dc.identifier.epage450en_US
dc.identifier.isiWOS:000225878000018-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChim, CS=7004597253en_US
dc.identifier.scopusauthoridMa, SK=37020910400en_US
dc.identifier.issnl1026-8022-

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