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Article: Innate immunity and systemic lupus erythematosus

TitleInnate immunity and systemic lupus erythematosus
Authors
KeywordsDisease Aetiology And Pathogenesis
Innate Immunity
Lymphocyte Activation
Systemic Lupus Erythematous
Issue Date2006
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APL
Citation
Aplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 359-364 How to Cite?
AbstractInnate immunity is the first-line host defence against pathogens and damaged host cells, and the major cellular components are phagocytes such as monocytes/macrophages, polymorphonuclear cells and dendritic cells. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of tolerance to self-antigens, the source of which has been suggested to be apoptotic cells. In this article, we will review studies on apoptosis in SLE and discuss the contribution of innate immunity abnormalities in the development of this condition. © 2006 Asia Pacific League of Associations for Rheumatology.
Persistent Identifierhttp://hdl.handle.net/10722/163044
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorJin, Oen_US
dc.contributor.authorSun, Len_US
dc.contributor.authorKavikondala, Sen_US
dc.contributor.authorLau, CSen_US
dc.date.accessioned2012-09-05T05:26:54Z-
dc.date.available2012-09-05T05:26:54Z-
dc.date.issued2006en_US
dc.identifier.citationAplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 359-364en_US
dc.identifier.issn0219-0494en_US
dc.identifier.urihttp://hdl.handle.net/10722/163044-
dc.description.abstractInnate immunity is the first-line host defence against pathogens and damaged host cells, and the major cellular components are phagocytes such as monocytes/macrophages, polymorphonuclear cells and dendritic cells. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of tolerance to self-antigens, the source of which has been suggested to be apoptotic cells. In this article, we will review studies on apoptosis in SLE and discuss the contribution of innate immunity abnormalities in the development of this condition. © 2006 Asia Pacific League of Associations for Rheumatology.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APLen_US
dc.relation.ispartofAPLAR Journal of Rheumatologyen_US
dc.subjectDisease Aetiology And Pathogenesisen_US
dc.subjectInnate Immunityen_US
dc.subjectLymphocyte Activationen_US
dc.subjectSystemic Lupus Erythematousen_US
dc.titleInnate immunity and systemic lupus erythematosusen_US
dc.typeArticleen_US
dc.identifier.emailLau, CS:cslau@hku.hken_US
dc.identifier.authorityLau, CS=rp01348en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1479-8077.2006.00229.xen_US
dc.identifier.scopuseid_2-s2.0-33750991860en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33750991860&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume9en_US
dc.identifier.issue4en_US
dc.identifier.spage359en_US
dc.identifier.epage364en_US
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridJin, O=7004432895en_US
dc.identifier.scopusauthoridSun, L=35265069800en_US
dc.identifier.scopusauthoridKavikondala, S=14819602600en_US
dc.identifier.scopusauthoridLau, CS=14035682100en_US
dc.identifier.issnl0219-0494-

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