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- Publisher Website: 10.1016/j.hrthm.2009.02.025
- Scopus: eid_2-s2.0-65649133577
- PMID: 19427274
- WOS: WOS:000266658800004
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Article: Temporary leadless pacing in heart failure patients with ultrasound-mediated stimulation energy and effects on the acoustic window
Title | Temporary leadless pacing in heart failure patients with ultrasound-mediated stimulation energy and effects on the acoustic window |
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Authors | |
Keywords | Cardiac resynchronization therapy Heart failure Pacing Ultrasound energy |
Issue Date | 2009 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/heartrhythmjournal |
Citation | Heart Rhythm, 2009, v. 6 n. 6, p. 742-748 How to Cite? |
Abstract | Background: Left ventricular stimulation for cardiac resynchronization therapy is largely limited by access and anatomy of coronary veins. Objective: This study sought to apply ultrasound-mediated leadless pacing technology in heart failure patients and to evaluate the effects of respiration and body posture on the acoustic window. Methods: Patients with advanced heart failure and ejection fraction ≤35% were studied. An electrophysiology catheter incorporating a receiver electrode to deliver ultrasound-mediated pacing was positioned in the left ventricle. Ultrasound-mediated pacing thresholds were determined. The acoustic windows on the chest wall with the patient lying supine, titled 30° leftward, 30° rightward, and 30° upward were determined. The acoustic windows were also determined with computed tomography and transthoracic echocardiography. Simulated receiver movement with respiratory movement and body positioning was assessed with computed tomography. Results: Ten patients were studied. Ultrasound-mediated pacing was successful in all patients. The acoustic window measured 39.6 ± 18.2 cm2. The window size decreased with rightward tilt, and increased with leftward and upward tilt. They correlated with measurements made by transthoracic echocardiography and computed tomography. Target receiver movement of 1.2 ± 1.4 cm horizontally and 1.3 ± 0.8 cm vertically were estimated by computed tomography. Conclusion: The feasibility of leadless left ventricular stimulation was shown acutely in heart failure patients. The acoustic window validated by computed tomography was predicted by transthoracic echocardiography. Effects of respiration and body posture were evaluated for development of the future implantable device. © 2009 Heart Rhythm Society. |
Persistent Identifier | http://hdl.handle.net/10722/163245 |
ISSN | 2021 Impact Factor: 6.779 2020 SCImago Journal Rankings: 2.768 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, KL | en_US |
dc.contributor.author | Tse, HF | en_US |
dc.contributor.author | Echt, DS | en_US |
dc.contributor.author | Lau, CP | en_US |
dc.date.accessioned | 2012-09-05T05:29:06Z | - |
dc.date.available | 2012-09-05T05:29:06Z | - |
dc.date.issued | 2009 | en_US |
dc.identifier.citation | Heart Rhythm, 2009, v. 6 n. 6, p. 742-748 | en_US |
dc.identifier.issn | 1547-5271 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/163245 | - |
dc.description.abstract | Background: Left ventricular stimulation for cardiac resynchronization therapy is largely limited by access and anatomy of coronary veins. Objective: This study sought to apply ultrasound-mediated leadless pacing technology in heart failure patients and to evaluate the effects of respiration and body posture on the acoustic window. Methods: Patients with advanced heart failure and ejection fraction ≤35% were studied. An electrophysiology catheter incorporating a receiver electrode to deliver ultrasound-mediated pacing was positioned in the left ventricle. Ultrasound-mediated pacing thresholds were determined. The acoustic windows on the chest wall with the patient lying supine, titled 30° leftward, 30° rightward, and 30° upward were determined. The acoustic windows were also determined with computed tomography and transthoracic echocardiography. Simulated receiver movement with respiratory movement and body positioning was assessed with computed tomography. Results: Ten patients were studied. Ultrasound-mediated pacing was successful in all patients. The acoustic window measured 39.6 ± 18.2 cm2. The window size decreased with rightward tilt, and increased with leftward and upward tilt. They correlated with measurements made by transthoracic echocardiography and computed tomography. Target receiver movement of 1.2 ± 1.4 cm horizontally and 1.3 ± 0.8 cm vertically were estimated by computed tomography. Conclusion: The feasibility of leadless left ventricular stimulation was shown acutely in heart failure patients. The acoustic window validated by computed tomography was predicted by transthoracic echocardiography. Effects of respiration and body posture were evaluated for development of the future implantable device. © 2009 Heart Rhythm Society. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/heartrhythmjournal | en_US |
dc.relation.ispartof | Heart Rhythm | en_US |
dc.rights | Heart Rhythm. Copyright © Elsevier Inc. | - |
dc.subject | Cardiac resynchronization therapy | - |
dc.subject | Heart failure | - |
dc.subject | Pacing | - |
dc.subject | Ultrasound energy | - |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Cardiac Pacing, Artificial - Methods | en_US |
dc.subject.mesh | Electrodes, Implanted | en_US |
dc.subject.mesh | Equipment Design | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Heart Failure - Therapy | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Pacemaker, Artificial | en_US |
dc.subject.mesh | Severity Of Illness Index | en_US |
dc.subject.mesh | Stroke Volume | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.subject.mesh | Treatment Outcome | en_US |
dc.subject.mesh | Ultrasonography, Interventional - Instrumentation | en_US |
dc.title | Temporary leadless pacing in heart failure patients with ultrasound-mediated stimulation energy and effects on the acoustic window | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tse, HF:hftse@hkucc.hku.hk | en_US |
dc.identifier.authority | Tse, HF=rp00428 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.hrthm.2009.02.025 | en_US |
dc.identifier.pmid | 19427274 | - |
dc.identifier.scopus | eid_2-s2.0-65649133577 | en_US |
dc.identifier.hkuros | 158848 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-65649133577&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.spage | 742 | en_US |
dc.identifier.epage | 748 | en_US |
dc.identifier.isi | WOS:000266658800004 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Lee, KL=7501505962 | en_US |
dc.identifier.scopusauthorid | Tse, HF=7006070805 | en_US |
dc.identifier.scopusauthorid | Echt, DS=7004097811 | en_US |
dc.identifier.scopusauthorid | Lau, CP=7401968501 | en_US |
dc.identifier.issnl | 1547-5271 | - |