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- Publisher Website: 10.1016/j.ccm.2010.02.001
- Scopus: eid_2-s2.0-77952928098
- PMID: 20488286
- WOS: WOS:000278868900008
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Article: Disorders of glucose metabolism in sleep-disordered breathing
Title | Disorders of glucose metabolism in sleep-disordered breathing |
---|---|
Authors | |
Keywords | Diabetes mellitus Disorders in glucose metabolism Insulin resistance Obesity Sleep-disordered breathing |
Issue Date | 2010 |
Publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/cchm |
Citation | Clinics In Chest Medicine, 2010, v. 31 n. 2, p. 271-285 How to Cite? |
Abstract | Despite proliferating literature, the exact relationship between obstructive sleep apnea (OSA) and alterations in glucose metabolism is still controversial. There is growing evidence to suggest that OSA imposes adverse effects on glucose metabolism, but the translation into clinical effect is not well delineated. Many potential mechanisms are being explored, mostly relating to peripheral tissue response to insulin and more recently regarding pancreatic β cell function of insulin secretion. The effect of OSA on glucose metabolism is likely to be influenced by many personal characteristics. Age, degree of adiposity, lifestyle, comorbidities, and even the stage of glucose disorder itself may modify the relationship between OSA and glucose metabolism. In the biologic system of the human body, all these interact to culminate in clinically relevant outcomes. © 2010 Elsevier Inc. |
Persistent Identifier | http://hdl.handle.net/10722/163317 |
ISSN | 2023 Impact Factor: 2.8 2023 SCImago Journal Rankings: 1.526 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lui, MMS | en_US |
dc.contributor.author | Ip, MSM | en_US |
dc.date.accessioned | 2012-09-05T05:29:58Z | - |
dc.date.available | 2012-09-05T05:29:58Z | - |
dc.date.issued | 2010 | en_US |
dc.identifier.citation | Clinics In Chest Medicine, 2010, v. 31 n. 2, p. 271-285 | en_US |
dc.identifier.issn | 0272-5231 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/163317 | - |
dc.description.abstract | Despite proliferating literature, the exact relationship between obstructive sleep apnea (OSA) and alterations in glucose metabolism is still controversial. There is growing evidence to suggest that OSA imposes adverse effects on glucose metabolism, but the translation into clinical effect is not well delineated. Many potential mechanisms are being explored, mostly relating to peripheral tissue response to insulin and more recently regarding pancreatic β cell function of insulin secretion. The effect of OSA on glucose metabolism is likely to be influenced by many personal characteristics. Age, degree of adiposity, lifestyle, comorbidities, and even the stage of glucose disorder itself may modify the relationship between OSA and glucose metabolism. In the biologic system of the human body, all these interact to culminate in clinically relevant outcomes. © 2010 Elsevier Inc. | en_US |
dc.language | eng | en_US |
dc.publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/cchm | en_US |
dc.relation.ispartof | Clinics in Chest Medicine | en_US |
dc.subject | Diabetes mellitus | - |
dc.subject | Disorders in glucose metabolism | - |
dc.subject | Insulin resistance | - |
dc.subject | Obesity | - |
dc.subject | Sleep-disordered breathing | - |
dc.subject.mesh | Anoxia - Physiopathology | en_US |
dc.subject.mesh | Autonomic Nervous System - Physiopathology | en_US |
dc.subject.mesh | Blood Glucose - Analysis | en_US |
dc.subject.mesh | Continuous Positive Airway Pressure | en_US |
dc.subject.mesh | Cytokines - Metabolism | en_US |
dc.subject.mesh | Diabetes Mellitus - Metabolism | en_US |
dc.subject.mesh | Diabetes Mellitus, Type 2 - Metabolism | en_US |
dc.subject.mesh | Fatty Acid-Binding Proteins - Physiology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Insulin Resistance | en_US |
dc.subject.mesh | Sleep Apnea Syndromes - Metabolism | en_US |
dc.subject.mesh | Sleep Apnea, Obstructive - Metabolism - Therapy | en_US |
dc.subject.mesh | Sleep Deprivation - Physiopathology | en_US |
dc.title | Disorders of glucose metabolism in sleep-disordered breathing | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ip, MSM:msmip@hku.hk | en_US |
dc.identifier.authority | Ip, MSM=rp00347 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.ccm.2010.02.001 | en_US |
dc.identifier.pmid | 20488286 | - |
dc.identifier.scopus | eid_2-s2.0-77952928098 | en_US |
dc.identifier.hkuros | 179241 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77952928098&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 271 | en_US |
dc.identifier.epage | 285 | en_US |
dc.identifier.isi | WOS:000278868900008 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Lui, MMS=26027035000 | en_US |
dc.identifier.scopusauthorid | Ip, MSM=7102423259 | en_US |
dc.identifier.issnl | 0272-5231 | - |