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Conference Paper: CYP2C19 genotype and the PPIs - Focus on rabeprazole

TitleCYP2C19 genotype and the PPIs - Focus on rabeprazole
Authors
Lim, PWYGoh, KLWong, BCY
KeywordsAcid-Related Disorders
Consistent Inhibition
Cyp4502c19 Genetic Polymorphism
Rabeprazole
Issue Date2005
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
Journal Of Gastroenterology And Hepatology, 2005, v. 20 SUPPL. 3, p. S22-S28 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1440-1746.2005.04167.x
AbstractAmongst all the proton pump inhibitors (PPI), the hepatic metabolism of rabeprazole is least dependent on the CYP4502C19 system. Rabeprazole is therefore the PPI least affected by CYP4502C19 genetic polymorphism. This unique feature of rabeprazole complements rabeprazole's fast onset of action, and may lead to profound and consistent inhibition of gastric acid secretion in the treatment of acid-related disorders. © 2005 Blackwell Publishing Asia Pty Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/163563
ISSN
0815-9319
2021 Impact Factor: 4.369
2020 SCImago Journal Rankings: 1.214
ISI Accession Number ID
WOS:000234896400007
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLim, PWYen_US
dc.contributor.authorGoh, KLen_US
dc.contributor.authorWong, BCYen_US
dc.date.accessioned2012-09-05T05:37:25Z-
dc.date.available2012-09-05T05:37:25Z-
dc.date.issued2005en_US
dc.identifier.citationJournal Of Gastroenterology And Hepatology, 2005, v. 20 SUPPL. 3, p. S22-S28en_US
dc.identifier.issn0815-9319en_US
dc.identifier.urihttp://hdl.handle.net/10722/163563-
dc.description.abstractAmongst all the proton pump inhibitors (PPI), the hepatic metabolism of rabeprazole is least dependent on the CYP4502C19 system. Rabeprazole is therefore the PPI least affected by CYP4502C19 genetic polymorphism. This unique feature of rabeprazole complements rabeprazole's fast onset of action, and may lead to profound and consistent inhibition of gastric acid secretion in the treatment of acid-related disorders. © 2005 Blackwell Publishing Asia Pty Ltd.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGHen_US
dc.relation.ispartofJournal of Gastroenterology and Hepatologyen_US
dc.subjectAcid-Related Disordersen_US
dc.subjectConsistent Inhibitionen_US
dc.subjectCyp4502c19 Genetic Polymorphismen_US
dc.subjectRabeprazoleen_US
dc.titleCYP2C19 genotype and the PPIs - Focus on rabeprazoleen_US
dc.typeConference_Paperen_US
dc.identifier.emailWong, BCY:bcywong@hku.hken_US
dc.identifier.authorityWong, BCY=rp00429en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1440-1746.2005.04167.xen_US
dc.identifier.scopuseid_2-s2.0-33645923112en_US
dc.identifier.hkuros117711-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645923112&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume20en_US
dc.identifier.issueSUPPL. 3en_US
dc.identifier.spageS22en_US
dc.identifier.epageS28en_US
dc.identifier.isiWOS:000234896400007-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridLim, PWY=7202592290en_US
dc.identifier.scopusauthoridGoh, KL=7201860992en_US
dc.identifier.scopusauthoridWong, BCY=7402023340en_US
dc.identifier.citeulike3012570-
dc.identifier.issnl0815-9319-

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