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- Publisher Website: 10.1186/2045-3701-2-21
- Scopus: eid_2-s2.0-84865140739
- PMID: 22709970
- WOS: WOS:000307512700001
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Article: From loss to gain: role for SUN1 in laminopathies
Title | From loss to gain: role for SUN1 in laminopathies |
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Authors | |
Issue Date | 2012 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cellandbioscience.com |
Citation | Cell & Bioscience, 2012, v. 2 n. 1, article no. 21 How to Cite? |
Abstract | Mutations in LMNA encoding lamins A and C are associated with at least 10 different degenerative disorders affecting diverse tissues, collectively called laminopathies. A recent study showed that mis-accumulation of SUN1 underlies the pathology of degenerative features in laminopathies, and concomitantly suggests a gain-of-function versus a loss-of-function model for the action of lamin A mutants. |
Persistent Identifier | http://hdl.handle.net/10722/163773 |
ISSN | 2023 Impact Factor: 6.1 2023 SCImago Journal Rankings: 1.836 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Liu, B | en_US |
dc.contributor.author | Jin, DY | en_US |
dc.contributor.author | Zhou, Z | en_US |
dc.date.accessioned | 2012-09-20T07:51:30Z | - |
dc.date.available | 2012-09-20T07:51:30Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Cell & Bioscience, 2012, v. 2 n. 1, article no. 21 | en_US |
dc.identifier.issn | 2045-3701 | - |
dc.identifier.uri | http://hdl.handle.net/10722/163773 | - |
dc.description.abstract | Mutations in LMNA encoding lamins A and C are associated with at least 10 different degenerative disorders affecting diverse tissues, collectively called laminopathies. A recent study showed that mis-accumulation of SUN1 underlies the pathology of degenerative features in laminopathies, and concomitantly suggests a gain-of-function versus a loss-of-function model for the action of lamin A mutants. | - |
dc.language | eng | en_US |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.cellandbioscience.com | - |
dc.relation.ispartof | Cell & Bioscience | en_US |
dc.rights | Cell & Bioscience. Copyright © BioMed Central Ltd. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | From loss to gain: role for SUN1 in laminopathies | en_US |
dc.type | Article | en_US |
dc.identifier.email | Liu, B: ppliew@hku.hk | en_US |
dc.identifier.email | Jin, DY: dyjin@hku.hk | en_US |
dc.identifier.email | Zhou, Z: zhongjun@hkucc.hku.hk | en_US |
dc.identifier.authority | Liu, B=rp01485 | en_US |
dc.identifier.authority | Jin, D=rp00452 | en_US |
dc.identifier.authority | Zhou, Z=rp00503 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/2045-3701-2-21 | - |
dc.identifier.pmid | 22709970 | - |
dc.identifier.pmcid | PMC3419603 | - |
dc.identifier.scopus | eid_2-s2.0-84865140739 | - |
dc.identifier.hkuros | 207818 | en_US |
dc.identifier.volume | 2 | en_US |
dc.identifier.issue | 1, article no. 21 | - |
dc.identifier.isi | WOS:000307512700001 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2045-3701 | - |