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- Publisher Website: 10.1016/j.rmed.2012.05.009
- Scopus: eid_2-s2.0-84865202412
- PMID: 22795505
- WOS: WOS:000309147400010
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Article: Past dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Study
Title | Past dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Study |
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Authors | |
Keywords | Chinese Chronic obstructive lung disease Coughing Dust exposure Dyspnea |
Issue Date | 2012 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/rmed |
Citation | Respiratory Medicine, 2012, v. 106 n. 10, p. 1421-1428 How to Cite? |
Abstract | The impact of occupational dust and gas/fume exposure on chronic obstructive pulmonary disease (COPD) in developing countries has not been quantified. We examined the relationship between past dust and fume exposure and prevalence of COPD and respiratory symptoms in a cross-sectional analysis of a large Chinese population sample. Participants in the Guangzhou Biobank Cohort Study (n = 8216; 27.3% men, mean age 61.9 +/- 6.8 years) had spirometry and a structured interview including exposures, symptoms, and lifestyle. Self-reported intensity and duration of dust and gas/fume exposure was used to derive cumulative exposure. COPD was diagnosed from spirometry using lower limit of normal based on prediction equations. COPD was associated with high exposure to dust or gas/fume (exposed: 87/1206 v non-exposed: 191/3853; adjusted odds ratio: 1.41; 95% confidence interval (CI) 1.06, 1.87) with no evidence of effect modification by smoking. Respiratory symptoms were associated with exposures to dust and gas/fume, with adjusted odds ratios for chronic cough/phlegm of 1.57 (1.13, 2.17) and 1.39 (1.20, 1.60) for dyspnoea. The overall population attributable fraction for COPD due to occupational exposure was 10.4% (95% CI -0.9%, 19.5%). Occupational dust and gas/fume exposure is associated with an increased prevalence of COPD in this Chinese sample, independent of smoking. The population attributable fraction in Chinese is similar to that in Western populations. |
Persistent Identifier | http://hdl.handle.net/10722/164800 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 1.180 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lam, KBH | en_US |
dc.contributor.author | Yin, P | en_US |
dc.contributor.author | Jiang, CQ | en_US |
dc.contributor.author | Zhang, WS | en_US |
dc.contributor.author | Adab, P | en_US |
dc.contributor.author | Miller, MR | en_US |
dc.contributor.author | Thomas, GN | en_US |
dc.contributor.author | Ayres, JG | en_US |
dc.contributor.author | Lam, TH | en_US |
dc.contributor.author | Cheng, KK | en_US |
dc.date.accessioned | 2012-09-20T08:09:42Z | - |
dc.date.available | 2012-09-20T08:09:42Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Respiratory Medicine, 2012, v. 106 n. 10, p. 1421-1428 | en_US |
dc.identifier.issn | 0954-6111 | - |
dc.identifier.uri | http://hdl.handle.net/10722/164800 | - |
dc.description.abstract | The impact of occupational dust and gas/fume exposure on chronic obstructive pulmonary disease (COPD) in developing countries has not been quantified. We examined the relationship between past dust and fume exposure and prevalence of COPD and respiratory symptoms in a cross-sectional analysis of a large Chinese population sample. Participants in the Guangzhou Biobank Cohort Study (n = 8216; 27.3% men, mean age 61.9 +/- 6.8 years) had spirometry and a structured interview including exposures, symptoms, and lifestyle. Self-reported intensity and duration of dust and gas/fume exposure was used to derive cumulative exposure. COPD was diagnosed from spirometry using lower limit of normal based on prediction equations. COPD was associated with high exposure to dust or gas/fume (exposed: 87/1206 v non-exposed: 191/3853; adjusted odds ratio: 1.41; 95% confidence interval (CI) 1.06, 1.87) with no evidence of effect modification by smoking. Respiratory symptoms were associated with exposures to dust and gas/fume, with adjusted odds ratios for chronic cough/phlegm of 1.57 (1.13, 2.17) and 1.39 (1.20, 1.60) for dyspnoea. The overall population attributable fraction for COPD due to occupational exposure was 10.4% (95% CI -0.9%, 19.5%). Occupational dust and gas/fume exposure is associated with an increased prevalence of COPD in this Chinese sample, independent of smoking. The population attributable fraction in Chinese is similar to that in Western populations. | - |
dc.language | eng | en_US |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/rmed | - |
dc.relation.ispartof | Respiratory Medicine | en_US |
dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication in <Journal title>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, [VOL#, ISSUE#, (DATE)] DOI# | - |
dc.subject | Chinese | - |
dc.subject | Chronic obstructive lung disease | - |
dc.subject | Coughing | - |
dc.subject | Dust exposure | - |
dc.subject | Dyspnea | - |
dc.title | Past dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Study | en_US |
dc.type | Article | en_US |
dc.identifier.email | Jiang, CQ: jcqiang@yahoo.com.cn | en_US |
dc.identifier.email | Lam, TH: hrmrlth@hkucc.hku.hk | en_US |
dc.identifier.authority | Lam, TH=rp00326 | en_US |
dc.identifier.doi | 10.1016/j.rmed.2012.05.009 | - |
dc.identifier.pmid | 22795505 | - |
dc.identifier.scopus | eid_2-s2.0-84865202412 | - |
dc.identifier.hkuros | 209802 | en_US |
dc.identifier.volume | 106 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.spage | 1421 | en_US |
dc.identifier.epage | 1428 | en_US |
dc.identifier.isi | WOS:000309147400010 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0954-6111 | - |