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Article: Excess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong

TitleExcess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong
Authors
KeywordsEpidemiology
influenza
statistics
Issue Date2012
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYG
Citation
Epidemiology and Infection, 2012, v. 140 n. 9, p. 1542-1550 How to Cite?
AbstractReliable estimates of the burden of 2009 pandemic influenza A(pH1N1) cannot be easily obtained because only a small fraction of infections were confirmed by laboratory tests in a timely manner. In this study we developed a Poisson prediction modelling approach to estimate the excess mortality associated with pH1N1 in 2009 and seasonal influenza in 1998-2008 in the subtropical city Hong Kong. The results suggested that there were 127 all-cause excess deaths associated with pH1N1, including 115 with cardiovascular and respiratory disease, and 22 with pneumonia and influenza. The excess mortality rates associated with pH1N1 were highest in the population aged >/=65 years. The mortality burden of influenza during the whole of 2009 was comparable to those in the preceding ten inter-pandemic years. The estimates of excess deaths were more than twofold higher than the reported fatal cases with laboratory-confirmed pH1N1 infection.
Persistent Identifierhttp://hdl.handle.net/10722/166781
ISSN
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.830
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYang, Len_HK
dc.contributor.authorChan, KPen_HK
dc.contributor.authorCowling, BJen_HK
dc.contributor.authorChiu, SSen_HK
dc.contributor.authorChan, KHen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorWong, CMen_HK
dc.date.accessioned2012-09-20T08:48:05Z-
dc.date.available2012-09-20T08:48:05Z-
dc.date.issued2012en_HK
dc.identifier.citationEpidemiology and Infection, 2012, v. 140 n. 9, p. 1542-1550en_HK
dc.identifier.issn0950-2688en_HK
dc.identifier.urihttp://hdl.handle.net/10722/166781-
dc.description.abstractReliable estimates of the burden of 2009 pandemic influenza A(pH1N1) cannot be easily obtained because only a small fraction of infections were confirmed by laboratory tests in a timely manner. In this study we developed a Poisson prediction modelling approach to estimate the excess mortality associated with pH1N1 in 2009 and seasonal influenza in 1998-2008 in the subtropical city Hong Kong. The results suggested that there were 127 all-cause excess deaths associated with pH1N1, including 115 with cardiovascular and respiratory disease, and 22 with pneumonia and influenza. The excess mortality rates associated with pH1N1 were highest in the population aged >/=65 years. The mortality burden of influenza during the whole of 2009 was comparable to those in the preceding ten inter-pandemic years. The estimates of excess deaths were more than twofold higher than the reported fatal cases with laboratory-confirmed pH1N1 infection.en_HK
dc.languageengen_US
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYGen_HK
dc.relation.ispartofEpidemiology and Infectionen_HK
dc.rightsEpidemiology and Infection. Copyright © Cambridge University Press.-
dc.subjectEpidemiology-
dc.subjectinfluenza-
dc.subjectstatistics-
dc.subject.meshCause of Deathen_HK
dc.subject.meshInfluenza A Virus, H1N1 Subtype - isolation and purificationen_HK
dc.subject.meshInfluenza, Human - complications - epidemiology - mortalityen_HK
dc.subject.meshModels, Biologicalen_HK
dc.subject.meshPandemicsen_HK
dc.titleExcess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailYang, L: linyang@hku.hken_HK
dc.identifier.emailChan, KP: kpchanaa@hku.hken_HK
dc.identifier.emailCowling, BJ: bcowling@hku.hken_HK
dc.identifier.emailChiu, SS: ssschiu@hku.hken_HK
dc.identifier.emailChan, KH: chankh2@hkucc.hku.hk-
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hk-
dc.identifier.emailWong, CM: hrmrwcm@hku.hk-
dc.identifier.authorityCowling, BJ=rp01326en_HK
dc.identifier.authorityChiu, SS=rp00421en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authorityWong, CM=rp00338en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1017/S0950268811002238en_HK
dc.identifier.pmid22074735-
dc.identifier.scopuseid_2-s2.0-84864469778en_HK
dc.identifier.hkuros208340en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84864469778&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume140en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1542en_HK
dc.identifier.epage1550en_HK
dc.identifier.isiWOS:000307283700002-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, CM=7404954904en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridChan, KH=14069945400en_HK
dc.identifier.scopusauthoridChiu, SS=7202291500en_HK
dc.identifier.scopusauthoridCowling, BJ=8644765500en_HK
dc.identifier.scopusauthoridChan, KP=27171298000en_HK
dc.identifier.scopusauthoridYang, L=7406279703en_HK
dc.identifier.issnl0950-2688-

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