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Article: Microphthalmos associated with Dartmouth combination chemotherapy in pregnancy: A case report

TitleMicrophthalmos associated with Dartmouth combination chemotherapy in pregnancy: A case report
Authors
Li, RHWWing, HTPak, CNMok, TSKTam, BTze, KL
KeywordsCombination chemotherapy
Melanoma
Metastasis
Microphthalmos
Pregnancy complications
Issue Date2007
PublisherJournal of Reproductive Medicine, Inc. The Journal's web site is located at http://www.reproductivemedicine.com
Citation
Journal Of Reproductive Medicine For The Obstetrician And Gynecologist, 2007, v. 52 n. 6, p. 575-576 How to Cite?
AbstractBACKGROUND: Use of Dartmouth combination chemotherapy in pregnancy is scarcely reported, with only 1 report of its use in the late second and third trimesters and no report of its use in the first trimester. CASE: This is the first reported case in which the Dartmouth combination chemotherapy regimen was inadvertently used in a pregnant woman during the first and second trimesters for treatment of metastatic melanoma. The infant was found to have isolated microphthalmos and severe hypermetropia at 1 year of age. CONCLUSION: Although a causal relationship cannot be established from a single case, this report does provide useful information to discourage the use of this chemotherapy regimen in the first trimester, which is the critical period for organogenesis. © Journal of Reproductive Medicine®, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/167088
ISSN
0024-7758
2021 Impact Factor: 0.218
2020 SCImago Journal Rankings: 0.132
ISI Accession Number ID
WOS:000247354600029
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLi, RHWen_US
dc.contributor.authorWing, HTen_US
dc.contributor.authorPak, CNen_US
dc.contributor.authorMok, TSKen_US
dc.contributor.authorTam, Ben_US
dc.contributor.authorTze, KLen_US
dc.date.accessioned2012-09-28T04:03:37Z-
dc.date.available2012-09-28T04:03:37Z-
dc.date.issued2007en_US
dc.identifier.citationJournal Of Reproductive Medicine For The Obstetrician And Gynecologist, 2007, v. 52 n. 6, p. 575-576en_US
dc.identifier.issn0024-7758en_US
dc.identifier.urihttp://hdl.handle.net/10722/167088-
dc.description.abstractBACKGROUND: Use of Dartmouth combination chemotherapy in pregnancy is scarcely reported, with only 1 report of its use in the late second and third trimesters and no report of its use in the first trimester. CASE: This is the first reported case in which the Dartmouth combination chemotherapy regimen was inadvertently used in a pregnant woman during the first and second trimesters for treatment of metastatic melanoma. The infant was found to have isolated microphthalmos and severe hypermetropia at 1 year of age. CONCLUSION: Although a causal relationship cannot be established from a single case, this report does provide useful information to discourage the use of this chemotherapy regimen in the first trimester, which is the critical period for organogenesis. © Journal of Reproductive Medicine®, Inc.en_US
dc.languageengen_US
dc.publisherJournal of Reproductive Medicine, Inc. The Journal's web site is located at http://www.reproductivemedicine.comen_US
dc.relation.ispartofJournal of Reproductive Medicine for the Obstetrician and Gynecologisten_US
dc.subjectCombination chemotherapy-
dc.subjectMelanoma-
dc.subjectMetastasis-
dc.subjectMicrophthalmos-
dc.subjectPregnancy complications-
dc.subject.meshAdulten_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols - Adverse Effectsen_US
dc.subject.meshCarmustine - Adverse Effectsen_US
dc.subject.meshCisplatin - Adverse Effectsen_US
dc.subject.meshDacarbazine - Adverse Effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshLiver Neoplasms - Drug Therapy - Secondaryen_US
dc.subject.meshMaleen_US
dc.subject.meshMelanoma - Drug Therapy - Secondaryen_US
dc.subject.meshMicrophthalmos - Chemically Induceden_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Neoplastic - Drug Therapyen_US
dc.subject.meshPregnancy Trimester, First - Drug Effectsen_US
dc.subject.meshPregnancy Trimester, Second - Drug Effectsen_US
dc.subject.meshSkin Neoplasms - Drug Therapy - Pathologyen_US
dc.subject.meshTamoxifen - Adverse Effectsen_US
dc.titleMicrophthalmos associated with Dartmouth combination chemotherapy in pregnancy: A case reporten_US
dc.typeArticleen_US
dc.identifier.emailLi, RHW: raymondli@hku.hken_US
dc.identifier.authorityLi, RHW=rp01649en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid17694989-
dc.identifier.scopuseid_2-s2.0-34250793904en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34250793904&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume52en_US
dc.identifier.issue6en_US
dc.identifier.spage575en_US
dc.identifier.epage576en_US
dc.identifier.isiWOS:000247354600029-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLi, RHW=7404724295en_US
dc.identifier.scopusauthoridWing, HT=8564517100en_US
dc.identifier.scopusauthoridPak, CN=12345238900en_US
dc.identifier.scopusauthoridMok, TSK=7006561460en_US
dc.identifier.scopusauthoridTam, B=35973288900en_US
dc.identifier.scopusauthoridTze, KL=6507251018en_US
dc.identifier.issnl0024-7758-

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