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- Publisher Website: 10.1039/B303294A
- Scopus: eid_2-s2.0-0038639859
- PMID: 12877519
- WOS: WOS:000183872700050
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Article: Gold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells
Title | Gold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells |
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Authors | |
Issue Date | 2003 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp |
Citation | Chemical Communications, 2003, v. 9 n. 14, p. 1718-1719 How to Cite? |
Abstract | A series of gold(III) tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants; the gold-induced cytotoxicity occurs through an apoptotic pathway according to laser confocal microscopy and flow cytometric studies. |
Persistent Identifier | http://hdl.handle.net/10722/167802 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.133 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Che, CM | en_HK |
dc.contributor.author | Sun, RWY | en_HK |
dc.contributor.author | Yu, WY | en_HK |
dc.contributor.author | Ko, CB | en_HK |
dc.contributor.author | Zhu, N | en_HK |
dc.contributor.author | Sun, H | en_HK |
dc.date.accessioned | 2012-10-08T03:11:47Z | - |
dc.date.available | 2012-10-08T03:11:47Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | Chemical Communications, 2003, v. 9 n. 14, p. 1718-1719 | en_HK |
dc.identifier.issn | 1359-7345 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/167802 | - |
dc.description.abstract | A series of gold(III) tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants; the gold-induced cytotoxicity occurs through an apoptotic pathway according to laser confocal microscopy and flow cytometric studies. | en_HK |
dc.language | eng | en_US |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | en_HK |
dc.relation.ispartof | Chemical Communications | en_HK |
dc.title | Gold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Che, CM: cmche@hku.hk | en_HK |
dc.identifier.email | Sun, RWY: rwysun@hku.hk | en_HK |
dc.identifier.email | Zhu, N: nzhu@hkucc.hku.hk | en_HK |
dc.identifier.email | Sun, H: hsun@hku.hk | en_HK |
dc.identifier.authority | Che, CM=rp00670 | en_HK |
dc.identifier.authority | Sun, RWY=rp00781 | en_HK |
dc.identifier.authority | Zhu, N=rp00845 | en_HK |
dc.identifier.authority | Sun, H=rp00777 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1039/B303294A | - |
dc.identifier.pmid | 12877519 | - |
dc.identifier.scopus | eid_2-s2.0-0038639859 | en_HK |
dc.identifier.hkuros | 90965 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0038639859&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 9 | en_HK |
dc.identifier.issue | 14 | en_HK |
dc.identifier.spage | 1718 | en_HK |
dc.identifier.epage | 1719 | en_HK |
dc.identifier.isi | WOS:000183872700050 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Che, CM=7102442791 | en_HK |
dc.identifier.scopusauthorid | Sun, RWY=26325835800 | en_HK |
dc.identifier.scopusauthorid | Yu, WY=7403913673 | en_HK |
dc.identifier.scopusauthorid | Ko, CB=7202596810 | en_HK |
dc.identifier.scopusauthorid | Zhu, N=7201449530 | en_HK |
dc.identifier.scopusauthorid | Sun, H=7404827446 | en_HK |
dc.identifier.issnl | 1359-7345 | - |