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- Publisher Website: 10.1021/ol0265158
- Scopus: eid_2-s2.0-0041758456
- PMID: 12227766
- WOS: WOS:000178090700026
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Article: Novel intramolecular cyclopropanation reaction of unsaturated β-keto esters
Title | Novel intramolecular cyclopropanation reaction of unsaturated β-keto esters |
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Authors | |
Issue Date | 2002 |
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html |
Citation | Organic Letters, 2002, v. 4 n. 19, p. 3271-3274 How to Cite? |
Abstract | equation presented Fused cyclopropane β-keto esters are versatile intermediates for the synthesis of many biologically active natural products. Here we report a new intramolecular cyclopropanation reaction of unsaturated β-keto esters. In the presence of l 2, Et 3N, and Lewis acids such as Mg(CIO 4) 2 and Yb(OTf) 3, β-keto esters 1 bearing various olefin substituents were transformed to fused cyclopropanes 2 in a highly stereospecific manner with moderate to good yields. The mechanism of the reaction was also investigated. |
Persistent Identifier | http://hdl.handle.net/10722/167818 |
ISSN | 2023 Impact Factor: 4.9 2023 SCImago Journal Rankings: 1.245 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yang, D | en_US |
dc.contributor.author | Gao, Q | en_US |
dc.contributor.author | Lee, CS | en_US |
dc.contributor.author | Cheung, KK | en_US |
dc.date.accessioned | 2012-10-08T03:11:57Z | - |
dc.date.available | 2012-10-08T03:11:57Z | - |
dc.date.issued | 2002 | en_US |
dc.identifier.citation | Organic Letters, 2002, v. 4 n. 19, p. 3271-3274 | en_US |
dc.identifier.issn | 1523-7060 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/167818 | - |
dc.description.abstract | equation presented Fused cyclopropane β-keto esters are versatile intermediates for the synthesis of many biologically active natural products. Here we report a new intramolecular cyclopropanation reaction of unsaturated β-keto esters. In the presence of l 2, Et 3N, and Lewis acids such as Mg(CIO 4) 2 and Yb(OTf) 3, β-keto esters 1 bearing various olefin substituents were transformed to fused cyclopropanes 2 in a highly stereospecific manner with moderate to good yields. The mechanism of the reaction was also investigated. | en_US |
dc.language | eng | en_US |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html | en_US |
dc.relation.ispartof | Organic Letters | en_US |
dc.title | Novel intramolecular cyclopropanation reaction of unsaturated β-keto esters | en_US |
dc.type | Article | en_US |
dc.identifier.email | Yang, D:yangdan@hku.hk | en_US |
dc.identifier.authority | Yang, D=rp00825 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1021/ol0265158 | en_US |
dc.identifier.pmid | 12227766 | - |
dc.identifier.scopus | eid_2-s2.0-0041758456 | en_US |
dc.identifier.hkuros | 75917 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0041758456&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 4 | en_US |
dc.identifier.issue | 19 | en_US |
dc.identifier.spage | 3271 | en_US |
dc.identifier.epage | 3274 | en_US |
dc.identifier.isi | WOS:000178090700026 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Yang, D=7404800756 | en_US |
dc.identifier.scopusauthorid | Gao, Q=7202743913 | en_US |
dc.identifier.scopusauthorid | Lee, CS=35201187300 | en_US |
dc.identifier.scopusauthorid | Cheung, KK=7402406613 | en_US |
dc.identifier.issnl | 1523-7052 | - |