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- Publisher Website: 10.1039/b507114c
- Scopus: eid_2-s2.0-26944494498
- PMID: 16175289
- WOS: WOS:000232002900012
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Article: Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: Photoluminescent properties and cytotoxicities
Title | Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: Photoluminescent properties and cytotoxicities |
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Authors | |
Issue Date | 2005 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp |
Citation | Chemical Communications, 2005 n. 37, p. 4675-4677 How to Cite? |
Abstract | Platinum(n) terpyridine complexes with glycosylated acetylide and arylacetylide ligands bind to DNA with binding constants ∼10 5 mol -1 dm 3; the glycosylated arylacetylide complexes exhibit emission at λ max ≈ 620 nm in water and are up to ∼ 100-times higher in potency than the clinical cisplatin drug in killing cancer cells. © The Royal Society of Chemistry 2005. |
Persistent Identifier | http://hdl.handle.net/10722/167961 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.133 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ma, DL | en_US |
dc.contributor.author | Shum, TYT | en_US |
dc.contributor.author | Zhang, F | en_US |
dc.contributor.author | Che, CM | en_US |
dc.contributor.author | Yang, M | en_US |
dc.date.accessioned | 2012-10-08T03:13:28Z | - |
dc.date.available | 2012-10-08T03:13:28Z | - |
dc.date.issued | 2005 | en_US |
dc.identifier.citation | Chemical Communications, 2005 n. 37, p. 4675-4677 | en_US |
dc.identifier.issn | 1359-7345 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/167961 | - |
dc.description.abstract | Platinum(n) terpyridine complexes with glycosylated acetylide and arylacetylide ligands bind to DNA with binding constants ∼10 5 mol -1 dm 3; the glycosylated arylacetylide complexes exhibit emission at λ max ≈ 620 nm in water and are up to ∼ 100-times higher in potency than the clinical cisplatin drug in killing cancer cells. © The Royal Society of Chemistry 2005. | en_US |
dc.language | eng | en_US |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp | en_US |
dc.relation.ispartof | Chemical Communications | en_US |
dc.subject.mesh | Antineoplastic Agents - Chemical Synthesis - Pharmacology | en_US |
dc.subject.mesh | Cell Line, Tumor | en_US |
dc.subject.mesh | Chemistry, Physical | en_US |
dc.subject.mesh | Cisplatin - Pharmacology | en_US |
dc.subject.mesh | Dna - Chemistry - Metabolism | en_US |
dc.subject.mesh | Drug Screening Assays, Antitumor | en_US |
dc.subject.mesh | Electrophoresis, Polyacrylamide Gel | en_US |
dc.subject.mesh | Electrophoretic Mobility Shift Assay | en_US |
dc.subject.mesh | Glycosylation | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Ligands | en_US |
dc.subject.mesh | Luminescence | en_US |
dc.subject.mesh | Magnetic Resonance Spectroscopy | en_US |
dc.subject.mesh | Molecular Conformation | en_US |
dc.subject.mesh | Organoplatinum Compounds - Chemical Synthesis - Pharmacology | en_US |
dc.subject.mesh | Photochemistry | en_US |
dc.subject.mesh | Physicochemical Phenomena | en_US |
dc.subject.mesh | Pyridines - Chemical Synthesis | en_US |
dc.subject.mesh | Restriction Mapping | en_US |
dc.subject.mesh | Solubility | en_US |
dc.subject.mesh | Spectrophotometry, Ultraviolet | en_US |
dc.title | Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: Photoluminescent properties and cytotoxicities | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ma, DL:edmondma@hku.hk | en_US |
dc.identifier.email | Che, CM:cmche@hku.hk | en_US |
dc.identifier.authority | Ma, DL=rp00760 | en_US |
dc.identifier.authority | Che, CM=rp00670 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1039/b507114c | en_US |
dc.identifier.pmid | 16175289 | - |
dc.identifier.scopus | eid_2-s2.0-26944494498 | en_US |
dc.identifier.hkuros | 117975 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-26944494498&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.issue | 37 | en_US |
dc.identifier.spage | 4675 | en_US |
dc.identifier.epage | 4677 | en_US |
dc.identifier.isi | WOS:000232002900012 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Ma, DL=7402075538 | en_US |
dc.identifier.scopusauthorid | Shum, TYT=8922482200 | en_US |
dc.identifier.scopusauthorid | Zhang, F=40861854700 | en_US |
dc.identifier.scopusauthorid | Che, CM=7102442791 | en_US |
dc.identifier.scopusauthorid | Yang, M=7404925734 | en_US |
dc.identifier.issnl | 1359-7345 | - |