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Article: MicroRNA expression profiles and functions in the brain
Title | MicroRNA expression profiles and functions in the brain |
---|---|
Authors | |
Keywords | Epigenetic Control Neural Cell Specification Neurogenesis Posttranscriptional Regulator Synaptic Plasticity |
Issue Date | 2008 |
Publisher | Neural Regeneration Research. The Journal's web site is located at http://www.sjzsyj.com |
Citation | Neural Regeneration Research, 2008, v. 3 n. 12, p. 1380-1385 How to Cite? |
Abstract | MicroRNAs are abundant in the brains of vertebrates and some show a brain-specific or brain-enriched expression pattern. Because microRNAs regulate the expression of hundreds of target genes, it is not surprising that they have profoundly important functions in brain development and pathological processes. For example, miR-124 plays an important role in inducing and maintaining neuronal identity through targeting at least two anti-neural factors. MicroRNAs have also been implicated in brain disorders, including brain tumors and neurodegenerative diseases. This review aims to present an overview of the expression profiles and functions of microRNAs in the developing brains of vertebrates. |
Persistent Identifier | http://hdl.handle.net/10722/168401 |
ISSN | 2023 Impact Factor: 5.9 2023 SCImago Journal Rankings: 0.967 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Qi, Y | en_US |
dc.contributor.author | Zhao, Y | en_US |
dc.contributor.author | Chen, Z | en_US |
dc.contributor.author | Chen, X | en_US |
dc.contributor.author | Lin, MC | en_US |
dc.contributor.author | Kong, X | en_US |
dc.contributor.author | Lai, L | en_US |
dc.date.accessioned | 2012-10-08T03:18:31Z | - |
dc.date.available | 2012-10-08T03:18:31Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Neural Regeneration Research, 2008, v. 3 n. 12, p. 1380-1385 | en_US |
dc.identifier.issn | 1673-5374 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/168401 | - |
dc.description.abstract | MicroRNAs are abundant in the brains of vertebrates and some show a brain-specific or brain-enriched expression pattern. Because microRNAs regulate the expression of hundreds of target genes, it is not surprising that they have profoundly important functions in brain development and pathological processes. For example, miR-124 plays an important role in inducing and maintaining neuronal identity through targeting at least two anti-neural factors. MicroRNAs have also been implicated in brain disorders, including brain tumors and neurodegenerative diseases. This review aims to present an overview of the expression profiles and functions of microRNAs in the developing brains of vertebrates. | en_US |
dc.language | eng | en_US |
dc.publisher | Neural Regeneration Research. The Journal's web site is located at http://www.sjzsyj.com | en_US |
dc.relation.ispartof | Neural Regeneration Research | en_US |
dc.subject | Epigenetic Control | en_US |
dc.subject | Neural Cell Specification | en_US |
dc.subject | Neurogenesis | en_US |
dc.subject | Posttranscriptional Regulator | en_US |
dc.subject | Synaptic Plasticity | en_US |
dc.title | MicroRNA expression profiles and functions in the brain | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lin, MC:mcllin@hkucc.hku.hk | en_US |
dc.identifier.authority | Lin, MC=rp00746 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-69749112472 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-69749112472&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 3 | en_US |
dc.identifier.issue | 12 | en_US |
dc.identifier.spage | 1380 | en_US |
dc.identifier.epage | 1385 | en_US |
dc.publisher.place | China | en_US |
dc.identifier.scopusauthorid | Qi, Y=24171887800 | en_US |
dc.identifier.scopusauthorid | Zhao, Y=7406634118 | en_US |
dc.identifier.scopusauthorid | Chen, Z=34767856800 | en_US |
dc.identifier.scopusauthorid | Chen, X=24170717900 | en_US |
dc.identifier.scopusauthorid | Lin, MC=7404816359 | en_US |
dc.identifier.scopusauthorid | Kong, X=34768504800 | en_US |
dc.identifier.scopusauthorid | Lai, L=12445800200 | en_US |
dc.identifier.issnl | 1673-5374 | - |