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Article: MicroRNA expression profiles and functions in the brain

TitleMicroRNA expression profiles and functions in the brain
Authors
Qi, YZhao, YChen, ZChen, XLin, MCKong, XLai, L
KeywordsEpigenetic Control
Neural Cell Specification
Neurogenesis
Posttranscriptional Regulator
Synaptic Plasticity
Issue Date2008
PublisherNeural Regeneration Research. The Journal's web site is located at http://www.sjzsyj.com
Citation
Neural Regeneration Research, 2008, v. 3 n. 12, p. 1380-1385 How to Cite?
AbstractMicroRNAs are abundant in the brains of vertebrates and some show a brain-specific or brain-enriched expression pattern. Because microRNAs regulate the expression of hundreds of target genes, it is not surprising that they have profoundly important functions in brain development and pathological processes. For example, miR-124 plays an important role in inducing and maintaining neuronal identity through targeting at least two anti-neural factors. MicroRNAs have also been implicated in brain disorders, including brain tumors and neurodegenerative diseases. This review aims to present an overview of the expression profiles and functions of microRNAs in the developing brains of vertebrates.
Persistent Identifierhttp://hdl.handle.net/10722/168401
ISSN
1673-5374
2023 Impact Factor: 5.9
2023 SCImago Journal Rankings: 0.967
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorQi, Yen_US
dc.contributor.authorZhao, Yen_US
dc.contributor.authorChen, Zen_US
dc.contributor.authorChen, Xen_US
dc.contributor.authorLin, MCen_US
dc.contributor.authorKong, Xen_US
dc.contributor.authorLai, Len_US
dc.date.accessioned2012-10-08T03:18:31Z-
dc.date.available2012-10-08T03:18:31Z-
dc.date.issued2008en_US
dc.identifier.citationNeural Regeneration Research, 2008, v. 3 n. 12, p. 1380-1385en_US
dc.identifier.issn1673-5374en_US
dc.identifier.urihttp://hdl.handle.net/10722/168401-
dc.description.abstractMicroRNAs are abundant in the brains of vertebrates and some show a brain-specific or brain-enriched expression pattern. Because microRNAs regulate the expression of hundreds of target genes, it is not surprising that they have profoundly important functions in brain development and pathological processes. For example, miR-124 plays an important role in inducing and maintaining neuronal identity through targeting at least two anti-neural factors. MicroRNAs have also been implicated in brain disorders, including brain tumors and neurodegenerative diseases. This review aims to present an overview of the expression profiles and functions of microRNAs in the developing brains of vertebrates.en_US
dc.languageengen_US
dc.publisherNeural Regeneration Research. The Journal's web site is located at http://www.sjzsyj.comen_US
dc.relation.ispartofNeural Regeneration Researchen_US
dc.subjectEpigenetic Controlen_US
dc.subjectNeural Cell Specificationen_US
dc.subjectNeurogenesisen_US
dc.subjectPosttranscriptional Regulatoren_US
dc.subjectSynaptic Plasticityen_US
dc.titleMicroRNA expression profiles and functions in the brainen_US
dc.typeArticleen_US
dc.identifier.emailLin, MC:mcllin@hkucc.hku.hken_US
dc.identifier.authorityLin, MC=rp00746en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-69749112472en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-69749112472&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume3en_US
dc.identifier.issue12en_US
dc.identifier.spage1380en_US
dc.identifier.epage1385en_US
dc.publisher.placeChinaen_US
dc.identifier.scopusauthoridQi, Y=24171887800en_US
dc.identifier.scopusauthoridZhao, Y=7406634118en_US
dc.identifier.scopusauthoridChen, Z=34767856800en_US
dc.identifier.scopusauthoridChen, X=24170717900en_US
dc.identifier.scopusauthoridLin, MC=7404816359en_US
dc.identifier.scopusauthoridKong, X=34768504800en_US
dc.identifier.scopusauthoridLai, L=12445800200en_US
dc.identifier.issnl1673-5374-

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