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Conference Paper: Metabolite profiling using a novel QqQ linear ion trap mass spectrometer

TitleMetabolite profiling using a novel QqQ linear ion trap mass spectrometer
Authors
Flarakos, TReimer, MLJLeblanc, YChu, IK
Issue Date2002
Citation
Proceedings 50Th Asms Conference On Mass Spectrometry And Allied Topics, 2002, p. 627-628 How to Cite?
AbstractA novel hybrid RF/DC quadrupole-linear ion trap mass spectrometer (QqQ linear ion trap) was developed for analizing metabolite profiling. Primary hepatocyte incubations were used to demonstrate the utility of the QqQ linear ion trap mass spectrometer for metabolite profiling. High sensitivity in full scan mode MS, MS 2 and MS 3 modes, was provided by the ion trap scan functions of the QqQ linear ion trap. The flexibility to simultaneously perform quantitative and qualitative analysis was provided by MRM scan function. The experimental results show that seven major metabolites were observed during incubations.
Persistent Identifierhttp://hdl.handle.net/10722/168826

 

DC FieldValueLanguage
dc.contributor.authorFlarakos, Ten_US
dc.contributor.authorReimer, MLJen_US
dc.contributor.authorLeblanc, Yen_US
dc.contributor.authorChu, IKen_US
dc.date.accessioned2012-10-08T03:34:43Z-
dc.date.available2012-10-08T03:34:43Z-
dc.date.issued2002en_US
dc.identifier.citationProceedings 50Th Asms Conference On Mass Spectrometry And Allied Topics, 2002, p. 627-628en_US
dc.identifier.urihttp://hdl.handle.net/10722/168826-
dc.description.abstractA novel hybrid RF/DC quadrupole-linear ion trap mass spectrometer (QqQ linear ion trap) was developed for analizing metabolite profiling. Primary hepatocyte incubations were used to demonstrate the utility of the QqQ linear ion trap mass spectrometer for metabolite profiling. High sensitivity in full scan mode MS, MS 2 and MS 3 modes, was provided by the ion trap scan functions of the QqQ linear ion trap. The flexibility to simultaneously perform quantitative and qualitative analysis was provided by MRM scan function. The experimental results show that seven major metabolites were observed during incubations.en_US
dc.languageengen_US
dc.relation.ispartofProceedings 50th ASMS Conference on Mass Spectrometry and Allied Topicsen_US
dc.titleMetabolite profiling using a novel QqQ linear ion trap mass spectrometeren_US
dc.typeConference_Paperen_US
dc.identifier.emailChu, IK:ivankchu@hku.hken_US
dc.identifier.authorityChu, IK=rp00683en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-2442719416en_US
dc.identifier.spage627en_US
dc.identifier.epage628en_US
dc.identifier.scopusauthoridFlarakos, T=6508387914en_US
dc.identifier.scopusauthoridReimer, MLJ=7004660068en_US
dc.identifier.scopusauthoridLeBlanc, Y=7004393955en_US
dc.identifier.scopusauthoridChu, IK=7103327484en_US

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