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Article: Developmental definition of MSCs: New insights into pending questions

TitleDevelopmental definition of MSCs: New insights into pending questions
Authors
Issue Date2011
PublisherMary Ann Liebert, Inc. Publishers. The Journal's web site is located at http://www.liebertpub.com/clo
Citation
Cellular Reprogramming, 2011, v. 13 n. 6, p. 465-472 How to Cite?
AbstractMesenchymal stem cells (MSCs) are a rare heterogeneous population of multipotent cells that can be isolated from many different adult and fetal tissues. They exhibit the capacity to give rise to cells of multiple lineages and are defined by their phenotype and functional properties, such as spindle-shaped morphology, adherence to plastic, immune response modulation capacity, and multilineage differentiation potential. Accordingly, MSCs have a wide range of promising applications in the treatment of autoimmune diseases, tissue repair, and regeneration. Recent studies have shed some light on the exact identity and native distribution of MSCs, whereas controversial results are still being reported, indicating the need for further review on their definition and origin. In this article, we summarize the important progress and describe some of our own relevant work on the developmental definition of MSCs. © 2011 Mary Ann Liebert, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/170189
ISSN
2023 Impact Factor: 1.2
2023 SCImago Journal Rankings: 0.316
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHuang, Sen_HK
dc.contributor.authorLeung, Ven_HK
dc.contributor.authorPeng, Sen_HK
dc.contributor.authorLi, Len_HK
dc.contributor.authorLu, FJen_HK
dc.contributor.authorWang, Ten_HK
dc.contributor.authorLu, Wen_HK
dc.contributor.authorCheung, KMCen_HK
dc.contributor.authorZhou, Gen_HK
dc.date.accessioned2012-10-30T06:05:58Z-
dc.date.available2012-10-30T06:05:58Z-
dc.date.issued2011en_HK
dc.identifier.citationCellular Reprogramming, 2011, v. 13 n. 6, p. 465-472en_HK
dc.identifier.issn2152-4971en_HK
dc.identifier.urihttp://hdl.handle.net/10722/170189-
dc.description.abstractMesenchymal stem cells (MSCs) are a rare heterogeneous population of multipotent cells that can be isolated from many different adult and fetal tissues. They exhibit the capacity to give rise to cells of multiple lineages and are defined by their phenotype and functional properties, such as spindle-shaped morphology, adherence to plastic, immune response modulation capacity, and multilineage differentiation potential. Accordingly, MSCs have a wide range of promising applications in the treatment of autoimmune diseases, tissue repair, and regeneration. Recent studies have shed some light on the exact identity and native distribution of MSCs, whereas controversial results are still being reported, indicating the need for further review on their definition and origin. In this article, we summarize the important progress and describe some of our own relevant work on the developmental definition of MSCs. © 2011 Mary Ann Liebert, Inc.en_HK
dc.languageengen_US
dc.publisherMary Ann Liebert, Inc. Publishers. The Journal's web site is located at http://www.liebertpub.com/cloen_HK
dc.relation.ispartofCellular Reprogrammingen_HK
dc.rightsThis is a copy of an article published in the [Cellular Reprogramming] © [2011] [copyright Mary Ann Liebert, Inc.]; [Cellular Reprogramming] is available online at: http://www.liebertonline.com.-
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshAutoimmune Diseases - Immunology - Therapyen_US
dc.subject.meshCell Differentiation - Physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMesenchymal Stem Cell Transplantationen_US
dc.subject.meshMesenchymal Stem Cells - Cytology - Physiologyen_US
dc.subject.meshMultipotent Stem Cells - Cytology - Physiologyen_US
dc.subject.meshRegeneration - Physiologyen_US
dc.titleDevelopmental definition of MSCs: New insights into pending questionsen_HK
dc.typeArticleen_HK
dc.identifier.emailLu, W:wwlu@hku.hken_US
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_US
dc.identifier.emailZhou, G:wormoscz@gmail.comen_US
dc.identifier.authorityLu, W=rp00411en_US
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.identifier.authorityZhou, G=rp00527en_US
dc.description.naturepublished_or_final_versionen_US
dc.identifier.doi10.1089/cell.2011.0045en_HK
dc.identifier.pmid21919705-
dc.identifier.pmcidPMC3229822-
dc.identifier.scopuseid_2-s2.0-83255166464en_HK
dc.identifier.hkuros234832-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-83255166464&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue6en_HK
dc.identifier.spage465en_HK
dc.identifier.epage472en_HK
dc.identifier.isiWOS:000298151100001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHuang, S=53982847500en_US
dc.identifier.scopusauthoridLeung, V=24504145500en_US
dc.identifier.scopusauthoridPeng, S=13402746900en_US
dc.identifier.scopusauthoridLi, L=54585599700en_US
dc.identifier.scopusauthoridLu, FJ=54585725700en_US
dc.identifier.scopusauthoridWang, T=7405564863en_US
dc.identifier.scopusauthoridLu, W=7404215221en_US
dc.identifier.scopusauthoridCheung, KMC=7402406754en_US
dc.identifier.scopusauthoridZhou, G=23394245100en_US
dc.identifier.issnl2152-4971-

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