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Article: Chronic granulomatous disease: A different pattern in Hong Kong?

TitleChronic granulomatous disease: A different pattern in Hong Kong?
Authors
KeywordsChinese
chronic granulomatous disease
genetic counselling
nitroblue tetrazolium test
prophylactic antibiotics
Issue Date1991
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPC
Citation
Journal Of Paediatrics And Child Health, 1991, v. 27 n. 4, p. 235-239 How to Cite?
AbstractFrom July 1988 to December 1989, six boys with chronic granulomatous disease were diagnosed in our institutions. Their clinical features were reviewed in order to delineate the pattern of infections which seems to have both similarities and differences when compared with published reports of Caucasian patients. The most striking difference was the lack of skin sepsis and chronic lymphadenitis in our six patients. Gram-negative organisms were the commonest pathogens while Staphylococci sp. were not isolated. Clinical features which should alert one to the diagnosis were also highlighted. Prophylactic co-trimoxazole was effective in reducing the frequency of bacterial infections. Early diagnosis is not only essential for optimal patient management but also for genetic counselling for the extended family.
Persistent Identifierhttp://hdl.handle.net/10722/170246
ISSN
2023 Impact Factor: 1.6
2023 SCImago Journal Rankings: 0.499
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, YLen_US
dc.contributor.authorWong, SNen_US
dc.contributor.authorLawton, JWMen_US
dc.contributor.authorChow, CBen_US
dc.date.accessioned2012-10-30T06:06:56Z-
dc.date.available2012-10-30T06:06:56Z-
dc.date.issued1991en_US
dc.identifier.citationJournal Of Paediatrics And Child Health, 1991, v. 27 n. 4, p. 235-239en_US
dc.identifier.issn1034-4810en_US
dc.identifier.urihttp://hdl.handle.net/10722/170246-
dc.description.abstractFrom July 1988 to December 1989, six boys with chronic granulomatous disease were diagnosed in our institutions. Their clinical features were reviewed in order to delineate the pattern of infections which seems to have both similarities and differences when compared with published reports of Caucasian patients. The most striking difference was the lack of skin sepsis and chronic lymphadenitis in our six patients. Gram-negative organisms were the commonest pathogens while Staphylococci sp. were not isolated. Clinical features which should alert one to the diagnosis were also highlighted. Prophylactic co-trimoxazole was effective in reducing the frequency of bacterial infections. Early diagnosis is not only essential for optimal patient management but also for genetic counselling for the extended family.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPCen_US
dc.relation.ispartofJournal of Paediatrics and Child Healthen_US
dc.subjectChinese-
dc.subjectchronic granulomatous disease-
dc.subjectgenetic counselling-
dc.subjectnitroblue tetrazolium test-
dc.subjectprophylactic antibiotics-
dc.subject.meshAnti-Bacterial Agents - Therapeutic Useen_US
dc.subject.meshBacterial Infections - Complications - Prevention & Controlen_US
dc.subject.meshGranulomatous Disease, Chronic - Diagnosis - Ethnology - Etiology - Prevention & Controlen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshTrimethoprim-Sulfamethoxazole Combination - Therapeutic Useen_US
dc.titleChronic granulomatous disease: A different pattern in Hong Kong?en_US
dc.typeArticleen_US
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_US
dc.identifier.authorityLau, YL=rp00361en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1440-1754.1991.tb00399.x-
dc.identifier.pmid1958423-
dc.identifier.scopuseid_2-s2.0-0025830981en_US
dc.identifier.volume27en_US
dc.identifier.issue4en_US
dc.identifier.spage235en_US
dc.identifier.epage239en_US
dc.identifier.isiWOS:A1991GF12700007-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridLau, YL=7201403380en_US
dc.identifier.scopusauthoridWong, SN=7404590305en_US
dc.identifier.scopusauthoridLawton, JWM=7102180792en_US
dc.identifier.scopusauthoridChow, CB=7402578582en_US
dc.identifier.issnl1034-4810-

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