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Article: Progesterone augments the venoconstrictor effect of Ruscus without altering adrenergic reactivity
Title | Progesterone augments the venoconstrictor effect of Ruscus without altering adrenergic reactivity |
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Authors | |
Keywords | canine saphenous veins oestrogen progesterone Ruscus-extract sympathomimetic amines venous contractility |
Issue Date | 1991 |
Publisher | Royal Society of Medicine Press Ltd. The Journal's web site is located at http://www.rsm.ac.uk/pub/phleb.htm |
Citation | Phlebology, 1991, v. 6 n. 4, p. 261-268 How to Cite? |
Abstract | Chronic administration of oestrogen and/or progesterone does not affect adrenergic neurotransmission or contractions initiated by sympathomimetic amines in the cutaneous venous smooth muscle of the dog. However, contractions initiated by the venotropic Ruscus-extract are enhance following chronic exposure to progesterone, an affect that can be reversed by oestrogen. The contractions are mediated by an adrenergic and non-adrenergic component. The adrenergic component is enhanced by progesterone and decreased by oestrogen; the non-adrenergic component is most prominent when the serum-levels of the female steroid hormones are low. |
Persistent Identifier | http://hdl.handle.net/10722/171040 |
ISSN | 2023 Impact Factor: 1.6 2023 SCImago Journal Rankings: 0.501 |
DC Field | Value | Language |
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dc.contributor.author | Miller, VM | en_US |
dc.contributor.author | Marcelon, G | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.date.accessioned | 2012-10-30T06:11:57Z | - |
dc.date.available | 2012-10-30T06:11:57Z | - |
dc.date.issued | 1991 | en_US |
dc.identifier.citation | Phlebology, 1991, v. 6 n. 4, p. 261-268 | en_US |
dc.identifier.issn | 0268-3555 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171040 | - |
dc.description.abstract | Chronic administration of oestrogen and/or progesterone does not affect adrenergic neurotransmission or contractions initiated by sympathomimetic amines in the cutaneous venous smooth muscle of the dog. However, contractions initiated by the venotropic Ruscus-extract are enhance following chronic exposure to progesterone, an affect that can be reversed by oestrogen. The contractions are mediated by an adrenergic and non-adrenergic component. The adrenergic component is enhanced by progesterone and decreased by oestrogen; the non-adrenergic component is most prominent when the serum-levels of the female steroid hormones are low. | en_US |
dc.language | eng | en_US |
dc.publisher | Royal Society of Medicine Press Ltd. The Journal's web site is located at http://www.rsm.ac.uk/pub/phleb.htm | en_US |
dc.relation.ispartof | Phlebology | en_US |
dc.subject | canine saphenous veins | - |
dc.subject | oestrogen | - |
dc.subject | progesterone | - |
dc.subject | Ruscus-extract | - |
dc.subject | sympathomimetic amines | - |
dc.subject | venous contractility | - |
dc.title | Progesterone augments the venoconstrictor effect of Ruscus without altering adrenergic reactivity | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-0026341240 | en_US |
dc.identifier.volume | 6 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 261 | en_US |
dc.identifier.epage | 268 | en_US |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Miller, VM=7201476816 | en_US |
dc.identifier.scopusauthorid | Marcelon, G=6603299586 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.issnl | 0268-3555 | - |