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- Publisher Website: 10.1016/0895-7061(95)00030-S
- Scopus: eid_2-s2.0-0029057222
- PMID: 7646842
- WOS: WOS:A1995RB67900005
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Article: Endothelial cell signaling and endothelial dysfunction
Title | Endothelial cell signaling and endothelial dysfunction |
---|---|
Authors | |
Keywords | endothelium G-proteins hypercholesterolemia Lipoproteins lysophosphatidylcholine nitric oxide |
Issue Date | 1995 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjhyper |
Citation | American Journal Of Hypertension, 1995, v. 8 n. 5 II SUPPL., p. 28S-41S How to Cite? |
Abstract | Endothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some, of the extracellular signaling mechanisms employed by normal endothelial cells to exert a protective influence in the vascular wall and those signals generated by dysfunctional cells to promote the atherosclerotic process. It will also discuss the intracellular processes that regulate the release/expression of these signals and that control the transformation of this protective cell to one that promotes the development of vascular disease. |
Persistent Identifier | http://hdl.handle.net/10722/171166 |
ISSN | 2023 Impact Factor: 3.2 2023 SCImago Journal Rankings: 0.925 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Flavahan, NA | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.date.accessioned | 2012-10-30T06:12:29Z | - |
dc.date.available | 2012-10-30T06:12:29Z | - |
dc.date.issued | 1995 | en_US |
dc.identifier.citation | American Journal Of Hypertension, 1995, v. 8 n. 5 II SUPPL., p. 28S-41S | en_US |
dc.identifier.issn | 0895-7061 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171166 | - |
dc.description.abstract | Endothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some, of the extracellular signaling mechanisms employed by normal endothelial cells to exert a protective influence in the vascular wall and those signals generated by dysfunctional cells to promote the atherosclerotic process. It will also discuss the intracellular processes that regulate the release/expression of these signals and that control the transformation of this protective cell to one that promotes the development of vascular disease. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjhyper | en_US |
dc.relation.ispartof | American Journal of Hypertension | en_US |
dc.subject | endothelium | - |
dc.subject | G-proteins | - |
dc.subject | hypercholesterolemia | - |
dc.subject | Lipoproteins | - |
dc.subject | lysophosphatidylcholine | - |
dc.subject | nitric oxide | - |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Endothelium, Vascular - Physiology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Muscle Contraction | en_US |
dc.subject.mesh | Muscle, Smooth, Vascular - Physiology | en_US |
dc.subject.mesh | Signal Transduction - Physiology | en_US |
dc.subject.mesh | Vascular Diseases - Physiopathology | en_US |
dc.title | Endothelial cell signaling and endothelial dysfunction | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0895-7061(95)00030-S | - |
dc.identifier.pmid | 7646842 | - |
dc.identifier.scopus | eid_2-s2.0-0029057222 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 5 II SUPPL. | en_US |
dc.identifier.spage | 28S | en_US |
dc.identifier.epage | 41S | en_US |
dc.identifier.isi | WOS:A1995RB67900005 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Flavahan, NA=7006398882 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.issnl | 0895-7061 | - |