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- Publisher Website: 10.1016/0920-1211(95)00022-3
- Scopus: eid_2-s2.0-0029094094
- PMID: 8536676
- WOS: WOS:A1995RV90000006
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Article: Retrospective study of vigabatrin and psychiatric behavioural disturbances
| Title | Retrospective study of vigabatrin and psychiatric behavioural disturbances |
|---|---|
| Authors | |
| Keywords | Adverse drug reactions Retrospective study Vigabatrin |
| Issue Date | 1995 |
| Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyres |
| Citation | Epilepsy Research, 1995, v. 21 n. 3, p. 227-230 How to Cite? |
| Abstract | Vigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring. |
| Persistent Identifier | http://hdl.handle.net/10722/171169 |
| ISSN | 2021 Impact Factor: 2.991 2020 SCImago Journal Rankings: 0.863 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Wong, ICK | en_US |
| dc.date.accessioned | 2012-10-30T06:12:30Z | - |
| dc.date.available | 2012-10-30T06:12:30Z | - |
| dc.date.issued | 1995 | en_US |
| dc.identifier.citation | Epilepsy Research, 1995, v. 21 n. 3, p. 227-230 | en_US |
| dc.identifier.issn | 0920-1211 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/171169 | - |
| dc.description.abstract | Vigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring. | en_US |
| dc.language | eng | en_US |
| dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyres | en_US |
| dc.relation.ispartof | Epilepsy Research | en_US |
| dc.subject | Adverse drug reactions | - |
| dc.subject | Retrospective study | - |
| dc.subject | Vigabatrin | - |
| dc.title | Retrospective study of vigabatrin and psychiatric behavioural disturbances | en_US |
| dc.type | Article | en_US |
| dc.description.nature | link_to_subscribed_fulltext | en_US |
| dc.identifier.doi | 10.1016/0920-1211(95)00022-3 | en_US |
| dc.identifier.pmid | 8536676 | - |
| dc.identifier.scopus | eid_2-s2.0-0029094094 | en_US |
| dc.identifier.volume | 21 | en_US |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.spage | 227 | en_US |
| dc.identifier.epage | 230 | en_US |
| dc.identifier.isi | WOS:A1995RV90000006 | - |
| dc.publisher.place | Netherlands | en_US |
| dc.identifier.issnl | 0920-1211 | - |