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- Publisher Website: 10.1677/joe.0.1000007
- Scopus: eid_2-s2.0-0021320425
- PMID: 6690645
- WOS: WOS:A1984RY96700002
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Article: Sex differences in the serum concentrations of testosterone in mice and hamsters during their critical periods of neural sexual differentiation
Title | Sex differences in the serum concentrations of testosterone in mice and hamsters during their critical periods of neural sexual differentiation |
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Authors | |
Issue Date | 1984 |
Publisher | Society for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.org |
Citation | Journal Of Endocrinology, 1984, v. 100 n. 1, p. 7-11 How to Cite? |
Abstract | Male and female mice and hamsters were decapitated 1-5 days after birth and serum concentrations of testosterone determined by radioimmunoassay. in the two species studied, serum levels of testosterone in male pups were significantly (p < 0.05) higher than those obtained in female neonates. this lends support to the hypothesis that circulating levels of testosterone play an important role in the process of neural sexual differentiation in rodents. Moreover, the sex differences in serum concentrations of testosterone in neonatal rodents together with the detectable levels of testosterone in female neonates may suggest that androgenization is a dose-dependent phenomenon. Aledternatively, they may indicate that a minimum concentration of the steroid must be present for androgenization to occur during the critical period of neural sexual differentiation and that this 'threshold' is exceeded in male but not in female rodents. |
Persistent Identifier | http://hdl.handle.net/10722/171489 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 1.159 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Pang, SF | en_US |
dc.contributor.author | Tang, F | en_US |
dc.date.accessioned | 2012-10-30T06:15:24Z | - |
dc.date.available | 2012-10-30T06:15:24Z | - |
dc.date.issued | 1984 | en_US |
dc.identifier.citation | Journal Of Endocrinology, 1984, v. 100 n. 1, p. 7-11 | en_US |
dc.identifier.issn | 0022-0795 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171489 | - |
dc.description.abstract | Male and female mice and hamsters were decapitated 1-5 days after birth and serum concentrations of testosterone determined by radioimmunoassay. in the two species studied, serum levels of testosterone in male pups were significantly (p < 0.05) higher than those obtained in female neonates. this lends support to the hypothesis that circulating levels of testosterone play an important role in the process of neural sexual differentiation in rodents. Moreover, the sex differences in serum concentrations of testosterone in neonatal rodents together with the detectable levels of testosterone in female neonates may suggest that androgenization is a dose-dependent phenomenon. Aledternatively, they may indicate that a minimum concentration of the steroid must be present for androgenization to occur during the critical period of neural sexual differentiation and that this 'threshold' is exceeded in male but not in female rodents. | en_US |
dc.language | eng | en_US |
dc.publisher | Society for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.org | en_US |
dc.relation.ispartof | Journal of Endocrinology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Animals, Newborn - Blood - Growth & Development | en_US |
dc.subject.mesh | Cricetinae - Blood | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mesocricetus - Blood - Growth & Development | en_US |
dc.subject.mesh | Mice | en_US |
dc.subject.mesh | Mice, Inbred Icr - Blood - Growth & Development | en_US |
dc.subject.mesh | Nervous System - Growth & Development | en_US |
dc.subject.mesh | Sex Characteristics | en_US |
dc.subject.mesh | Sex Differentiation | en_US |
dc.subject.mesh | Testosterone - Blood | en_US |
dc.title | Sex differences in the serum concentrations of testosterone in mice and hamsters during their critical periods of neural sexual differentiation | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tang, F:ftang@hkucc.hku.hk | en_US |
dc.identifier.authority | Tang, F=rp00327 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1677/joe.0.1000007 | - |
dc.identifier.pmid | 6690645 | - |
dc.identifier.scopus | eid_2-s2.0-0021320425 | en_US |
dc.identifier.volume | 100 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 7 | en_US |
dc.identifier.epage | 11 | en_US |
dc.identifier.isi | WOS:A1984RY96700002 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Pang, SF=7402528719 | en_US |
dc.identifier.scopusauthorid | Tang, F=7201979770 | en_US |
dc.identifier.issnl | 0022-0795 | - |