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Article: Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1

TitleChromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1
Authors
Lee, SMYTsui, SKWChan, KKKotaka, MLi, HYChim, SSCWaye, MMYFung, KPLee, CY
Issue Date1998
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0740-7750
Citation
Somatic Cell And Molecular Genetics, 1998, v. 24 n. 3, p. 197-202 How to Cite?
DOI: http://dx.doi.org/10.1023/B:SCAM.0000007122.03392.4b
AbstractFour-and-a-half LIM domain proteins (FHL) possess four tandem repeats of LIM domain and an extra zinc finger. FHL family LIM proteins are unique when compared with other LIM-only proteins because they possess an odd number of zinc fingers. In this study, the tissue distribution and chromosomal mapping of skeletal muscle LIM protein FHL3 were reported. When the FHL3 cDNA probe was used to hybridize with poly-(A) RNA of various human tissues, a very strong signal was detected in skeletal muscle, and virtually no signal could be detected in heart, brain, placenta, lung, liver, kidney and pancreas. Using radiation hybrid technique, FHL3 gene was mapped to the distal end of the short arm of chromosome 1 (123.26 cR from the top of the Chr1 linkage group) and this region (near 1p34) is related to several human malignancies.
Persistent Identifierhttp://hdl.handle.net/10722/171652
ISSN
0740-7750
ISI Accession Number ID
WOS:000079835900006
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLee, SMYen_US
dc.contributor.authorTsui, SKWen_US
dc.contributor.authorChan, KKen_US
dc.contributor.authorKotaka, Men_US
dc.contributor.authorLi, HYen_US
dc.contributor.authorChim, SSCen_US
dc.contributor.authorWaye, MMYen_US
dc.contributor.authorFung, KPen_US
dc.contributor.authorLee, CYen_US
dc.date.accessioned2012-10-30T06:16:10Z-
dc.date.available2012-10-30T06:16:10Z-
dc.date.issued1998en_US
dc.identifier.citationSomatic Cell And Molecular Genetics, 1998, v. 24 n. 3, p. 197-202en_US
dc.identifier.issn0740-7750en_US
dc.identifier.urihttp://hdl.handle.net/10722/171652-
dc.description.abstractFour-and-a-half LIM domain proteins (FHL) possess four tandem repeats of LIM domain and an extra zinc finger. FHL family LIM proteins are unique when compared with other LIM-only proteins because they possess an odd number of zinc fingers. In this study, the tissue distribution and chromosomal mapping of skeletal muscle LIM protein FHL3 were reported. When the FHL3 cDNA probe was used to hybridize with poly-(A) RNA of various human tissues, a very strong signal was detected in skeletal muscle, and virtually no signal could be detected in heart, brain, placenta, lung, liver, kidney and pancreas. Using radiation hybrid technique, FHL3 gene was mapped to the distal end of the short arm of chromosome 1 (123.26 cR from the top of the Chr1 linkage group) and this region (near 1p34) is related to several human malignancies.en_US
dc.languageengen_US
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0740-7750en_US
dc.relation.ispartofSomatic Cell and Molecular Geneticsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlotting, Northernen_US
dc.subject.meshChromosome Mappingen_US
dc.subject.meshChromosomes, Human, Pair 1 - Geneticsen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshGene Expression Regulationen_US
dc.subject.meshHomeodomain Proteins - Geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshHybrid Cellsen_US
dc.subject.meshIntracellular Signaling Peptides And Proteinsen_US
dc.subject.meshLim Domain Proteinsen_US
dc.subject.meshMiceen_US
dc.subject.meshMuscle Proteins - Geneticsen_US
dc.subject.meshMuscle, Skeletal - Metabolismen_US
dc.subject.meshRna, Messenger - Genetics - Metabolismen_US
dc.subject.meshTissue Distributionen_US
dc.titleChromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1en_US
dc.typeArticleen_US
dc.identifier.emailKotaka, M:masayo@hku.hken_US
dc.identifier.authorityKotaka, M=rp00293en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1023/B:SCAM.0000007122.03392.4ben_US
dc.identifier.pmid10226657-
dc.identifier.scopuseid_2-s2.0-0032417228en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032417228&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue3en_US
dc.identifier.spage197en_US
dc.identifier.epage202en_US
dc.identifier.isiWOS:000079835900006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLee, SMY=35233892600en_US
dc.identifier.scopusauthoridTsui, SKW=7004961364en_US
dc.identifier.scopusauthoridChan, KK=7406034649en_US
dc.identifier.scopusauthoridKotaka, M=6604073578en_US
dc.identifier.scopusauthoridLi, HY=12762326800en_US
dc.identifier.scopusauthoridChim, SSC=6701728226en_US
dc.identifier.scopusauthoridWaye, MMY=7006687733en_US
dc.identifier.scopusauthoridFung, KP=7202934739en_US
dc.identifier.scopusauthoridLee, CY=7410142857en_US
dc.identifier.issnl0740-7750-

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