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Article: The effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary

TitleThe effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary
Authors
Cheung, CYTang, F
Keywordsβ-Endorphin
Diabetes
Pituitary
Proopiomelanocortin mRNA
Rat
Streptozotocin
Issue Date1999
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neulet
Citation
Neuroscience Letters, 1999, v. 261 n. 1-2, p. 118-120 How to Cite?
DOI: http://dx.doi.org/10.1016/S0304-3940(98)01008-8
AbstractStreptozotocin-induced diabetes for 4 weeks resulted in a decrease in proopiomelanocortin (POMC) mRNA in both the anterior lobe (AL) and the neuro- intermediate lobe (NIL) of the rat pituitary. The β-endorphin levels decreased in the NIL but not in the AL. It is concluded that the synthesis of POMC in the pituitary is inhibited in diabetic rats and that there is a decrease in β-endorphin release from the anterior pituitary.
Persistent Identifierhttp://hdl.handle.net/10722/171669
ISSN
0304-3940
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.745
ISI Accession Number ID
WOS:000078809900030
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorCheung, CYen_HK
dc.contributor.authorTang, Fen_HK
dc.date.accessioned2012-10-30T06:16:15Z-
dc.date.available2012-10-30T06:16:15Z-
dc.date.issued1999en_HK
dc.identifier.citationNeuroscience Letters, 1999, v. 261 n. 1-2, p. 118-120en_HK
dc.identifier.issn0304-3940en_HK
dc.identifier.urihttp://hdl.handle.net/10722/171669-
dc.description.abstractStreptozotocin-induced diabetes for 4 weeks resulted in a decrease in proopiomelanocortin (POMC) mRNA in both the anterior lobe (AL) and the neuro- intermediate lobe (NIL) of the rat pituitary. The β-endorphin levels decreased in the NIL but not in the AL. It is concluded that the synthesis of POMC in the pituitary is inhibited in diabetic rats and that there is a decrease in β-endorphin release from the anterior pituitary.en_HK
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neuleten_HK
dc.relation.ispartofNeuroscience Lettersen_HK
dc.rightsNeuroscience Letters. Copyright © Elsevier Ireland Ltd.-
dc.subjectβ-Endorphinen_HK
dc.subjectDiabetesen_HK
dc.subjectPituitaryen_HK
dc.subjectProopiomelanocortin mRNAen_HK
dc.subjectRaten_HK
dc.subjectStreptozotocinen_HK
dc.subject.meshAnimalsen_US
dc.subject.meshBlood Glucoseen_US
dc.subject.meshDiabetes Mellitus, Experimental - Genetics - Metabolismen_US
dc.subject.meshGene Expression - Physiologyen_US
dc.subject.meshHypoglycemic Agents - Pharmacologyen_US
dc.subject.meshInsulin - Pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPituitary Gland - Chemistry - Physiologyen_US
dc.subject.meshPro-Opiomelanocortin - Geneticsen_US
dc.subject.meshRna, Messenger - Analysisen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Sprague-Dawleyen_US
dc.subject.meshBeta-Endorphin - Metabolismen_US
dc.titleThe effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitaryen_HK
dc.typeArticleen_HK
dc.identifier.emailCheung, CY: chungey@hkucc.hku.hken_HK
dc.identifier.emailTang, F: ftang@hkucc.hku.hken_HK
dc.identifier.authorityCheung, CY=rp00404en_HK
dc.identifier.authorityTang, F=rp00327en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0304-3940(98)01008-8en_HK
dc.identifier.pmid10081941-
dc.identifier.scopuseid_2-s2.0-0033548229en_HK
dc.identifier.hkuros44135-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033548229&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume261en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage118en_HK
dc.identifier.epage120en_HK
dc.identifier.isiWOS:000078809900030-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridCheung, CY=7202061836en_HK
dc.identifier.scopusauthoridTang, F=7201979770en_HK
dc.identifier.issnl0304-3940-

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