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Article: The neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologie
Title | The neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologie |
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Authors | |
Keywords | Functional Imaging Neurodevelopmental Neuropsychology Schizophrenia Structure |
Issue Date | 1996 |
Publisher | Blackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACN |
Citation | Acta Neuropsychiatrica, 1996, v. 8 n. 2, p. 25-34 How to Cite? |
Abstract | Severe schizophrenics as a group show subtle abnormalities of cerebral structure. Cerebral ventricular enlargement is the best replicated finding, and this tends to be associated with impairment of neuropsychological performance. The idea that these abnormalities have a neurodevelopmental origin gains indirect support from the, admittedly less consistent, evidence of abnormalities of cerebral asymmetry and of neuronal migration in adult schizophrenics, as well as from the behavioural, psychomotor, and cognitive impairments reported in pre-schizophrenic children. However, the relationship between childhood and adult neuropsychological and brain structural findings has not been proven, and we do not know whether only some schizophrenics have a developmental origin, or whether patients differ only in the degree of developmental impairment that they show. |
Persistent Identifier | http://hdl.handle.net/10722/171887 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 0.874 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chua, SE | en_US |
dc.contributor.author | Murray, RM | en_US |
dc.date.accessioned | 2012-10-30T06:18:12Z | - |
dc.date.available | 2012-10-30T06:18:12Z | - |
dc.date.issued | 1996 | en_US |
dc.identifier.citation | Acta Neuropsychiatrica, 1996, v. 8 n. 2, p. 25-34 | en_US |
dc.identifier.issn | 0924-2708 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171887 | - |
dc.description.abstract | Severe schizophrenics as a group show subtle abnormalities of cerebral structure. Cerebral ventricular enlargement is the best replicated finding, and this tends to be associated with impairment of neuropsychological performance. The idea that these abnormalities have a neurodevelopmental origin gains indirect support from the, admittedly less consistent, evidence of abnormalities of cerebral asymmetry and of neuronal migration in adult schizophrenics, as well as from the behavioural, psychomotor, and cognitive impairments reported in pre-schizophrenic children. However, the relationship between childhood and adult neuropsychological and brain structural findings has not been proven, and we do not know whether only some schizophrenics have a developmental origin, or whether patients differ only in the degree of developmental impairment that they show. | en_US |
dc.language | eng | en_US |
dc.publisher | Blackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACN | en_US |
dc.relation.ispartof | Acta Neuropsychiatrica | en_US |
dc.subject | Functional | en_US |
dc.subject | Imaging | en_US |
dc.subject | Neurodevelopmental | en_US |
dc.subject | Neuropsychology | en_US |
dc.subject | Schizophrenia | en_US |
dc.subject | Structure | en_US |
dc.title | The neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologie | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chua, SE:sechua@hku.hk | en_US |
dc.identifier.authority | Chua, SE=rp00438 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-0029906454 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0029906454&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 25 | en_US |
dc.identifier.epage | 34 | en_US |
dc.identifier.isi | WOS:A1996UW52900001 | - |
dc.publisher.place | Denmark | en_US |
dc.identifier.scopusauthorid | Chua, SE=7201550427 | en_US |
dc.identifier.scopusauthorid | Murray, RM=35406239400 | en_US |
dc.identifier.issnl | 0924-2708 | - |