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- Publisher Website: 10.1034/j.1600-0447.2000.102005342.x
- Scopus: eid_2-s2.0-0033765650
- PMID: 11098805
- WOS: WOS:000165160000005
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Article: Progressive deterioration of soft neurological signs in chronic schizophrenic patients
Title | Progressive deterioration of soft neurological signs in chronic schizophrenic patients |
---|---|
Authors | |
Keywords | Longitudinal studies Neurological manifestations Schizophrenia |
Issue Date | 2000 |
Publisher | Blackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACP |
Citation | Acta Psychiatrica Scandinavica, 2000, v. 102 n. 5, p. 342-349 How to Cite? |
Abstract | Objective: Neurological signs are found to be increased in schizophrenia in cross-sectional studies. Whether they progress with time is an important issue in addressing the course of the illness. Method: The current study investigated different groups of neurological signs in 43 stable chronic schizophrenic patients over a 3-year period using an operationalized instrument. Results: While symptoms and medication have remained largely unchanged in the 3-year period, significant increase in soft neurological signs (SNS) ('motor coordination', 'sensory integration' and 'disinhibition') has been observed. This contrasted with the stability of 'pyramidal', 'extrapyramidal', 'dyskinesia' and 'catatonia' signs. The increase in SNS appears not to be related to age, illness duration, symptoms or medication. Conclusion: This finding suggests that SNS represent a marker sensitive to a possible late deterioration process in the course of a schizophrenic illness. (C) Munksgaard 2000. |
Persistent Identifier | http://hdl.handle.net/10722/171896 |
ISSN | 2023 Impact Factor: 5.3 2023 SCImago Journal Rankings: 2.615 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chen, EYH | en_US |
dc.contributor.author | Kwok, CL | en_US |
dc.contributor.author | Au, JWY | en_US |
dc.contributor.author | Chen, RYL | en_US |
dc.contributor.author | Lau, BST | en_US |
dc.date.accessioned | 2012-10-30T06:18:17Z | - |
dc.date.available | 2012-10-30T06:18:17Z | - |
dc.date.issued | 2000 | en_US |
dc.identifier.citation | Acta Psychiatrica Scandinavica, 2000, v. 102 n. 5, p. 342-349 | en_US |
dc.identifier.issn | 0001-690X | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171896 | - |
dc.description.abstract | Objective: Neurological signs are found to be increased in schizophrenia in cross-sectional studies. Whether they progress with time is an important issue in addressing the course of the illness. Method: The current study investigated different groups of neurological signs in 43 stable chronic schizophrenic patients over a 3-year period using an operationalized instrument. Results: While symptoms and medication have remained largely unchanged in the 3-year period, significant increase in soft neurological signs (SNS) ('motor coordination', 'sensory integration' and 'disinhibition') has been observed. This contrasted with the stability of 'pyramidal', 'extrapyramidal', 'dyskinesia' and 'catatonia' signs. The increase in SNS appears not to be related to age, illness duration, symptoms or medication. Conclusion: This finding suggests that SNS represent a marker sensitive to a possible late deterioration process in the course of a schizophrenic illness. (C) Munksgaard 2000. | en_US |
dc.language | eng | en_US |
dc.publisher | Blackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACP | en_US |
dc.relation.ispartof | Acta Psychiatrica Scandinavica | en_US |
dc.subject | Longitudinal studies | - |
dc.subject | Neurological manifestations | - |
dc.subject | Schizophrenia | - |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Case-Control Studies | en_US |
dc.subject.mesh | Chronic Disease | en_US |
dc.subject.mesh | Disease Progression | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Follow-Up Studies | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Motor Skills Disorders - Etiology | en_US |
dc.subject.mesh | Multivariate Analysis | en_US |
dc.subject.mesh | Neurologic Examination | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.subject.mesh | Reflex, Abnormal | en_US |
dc.subject.mesh | Schizophrenia - Complications - Diagnosis - Physiopathology | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Progressive deterioration of soft neurological signs in chronic schizophrenic patients | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chen, EYH:eyhchen@hku.hk | en_US |
dc.identifier.authority | Chen, EYH=rp00392 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1034/j.1600-0447.2000.102005342.x | en_US |
dc.identifier.pmid | 11098805 | - |
dc.identifier.scopus | eid_2-s2.0-0033765650 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033765650&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 102 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 342 | en_US |
dc.identifier.epage | 349 | en_US |
dc.identifier.isi | WOS:000165160000005 | - |
dc.publisher.place | Denmark | en_US |
dc.identifier.scopusauthorid | Chen, EYH=7402315729 | en_US |
dc.identifier.scopusauthorid | Kwok, CL=35989055900 | en_US |
dc.identifier.scopusauthorid | Au, JWY=7101921208 | en_US |
dc.identifier.scopusauthorid | Chen, RYL=16635066600 | en_US |
dc.identifier.scopusauthorid | Lau, BST=7102223655 | en_US |
dc.identifier.citeulike | 10114182 | - |
dc.identifier.issnl | 0001-690X | - |