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Article: Tardive dyskinesia in the treatment of schizophrenia: The findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)

TitleTardive dyskinesia in the treatment of schizophrenia: The findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)
Authors
KeywordsEthnicity
Schizophrenia
Tardive dyskinesia
Issue Date2011
PublisherDustri-Verlag Dr. Karl Feistle. The Journal's web site is located at http://www.dustri.com/nc/journals-in-english/mag/int-journal-of-clinical-pharmacology-and-therapeutics.html
Citation
International Journal Of Clinical Pharmacology And Therapeutics, 2011, v. 49 n. 6, p. 382-387 How to Cite?
AbstractObjective: The aim of the study was to survey the frequency of tardive dyskinesia (TD) in patients with schizophrenia and its demographic and clinical correlates in selected Asian countries. Method: A total of 6,761 hospitalized schizophrenia patients in nine Asian countries and territories were examined from 2001 to 2009. TD was evaluated as "present" or "absent" according to the clinical judgment of experienced psychiatrists. The patients' socio-demographic and clinical characteristics and the prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results: The frequency of TD in the whole sample was 5.0% with wide variations between countries (0-14.9%). Multiple logistic regression analysis showed that the following variables were independently associated with TD: study time, study site, older age, male gender, more severe negative and extrapyramidal symptoms and less anticholinergic drugs. Conclusions: A generally low frequency of TD in Asian schizophrenia patients with inter-ethnic variations was recorded. It is unclear whether the low prevalence of TD compared with Western data is real or the result of it being insufficiently recognized. ©2011 Dustri-Verlag Dr. K. Feistle.
Persistent Identifierhttp://hdl.handle.net/10722/171965
ISSN
2023 Impact Factor: 0.9
2023 SCImago Journal Rankings: 0.261
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorXiang, YTen_US
dc.contributor.authorWang, CYen_US
dc.contributor.authorSi, TMen_US
dc.contributor.authorLee, EHMen_US
dc.contributor.authorHe, YLen_US
dc.contributor.authorUngvari, GSen_US
dc.contributor.authorChiu, HFKen_US
dc.contributor.authorYang, SYen_US
dc.contributor.authorChong, MYen_US
dc.contributor.authorTan, CHen_US
dc.contributor.authorKua, EHen_US
dc.contributor.authorFujii, Sen_US
dc.contributor.authorSim, Ken_US
dc.contributor.authorYong, KHen_US
dc.contributor.authorTrivedi, JKen_US
dc.contributor.authorChung, EKen_US
dc.contributor.authorUdomratn, Pen_US
dc.contributor.authorChee, KYen_US
dc.contributor.authorSartorius, Nen_US
dc.contributor.authorShinfuku, Nen_US
dc.date.accessioned2012-10-30T06:18:57Z-
dc.date.available2012-10-30T06:18:57Z-
dc.date.issued2011en_US
dc.identifier.citationInternational Journal Of Clinical Pharmacology And Therapeutics, 2011, v. 49 n. 6, p. 382-387en_US
dc.identifier.issn0946-1965en_US
dc.identifier.urihttp://hdl.handle.net/10722/171965-
dc.description.abstractObjective: The aim of the study was to survey the frequency of tardive dyskinesia (TD) in patients with schizophrenia and its demographic and clinical correlates in selected Asian countries. Method: A total of 6,761 hospitalized schizophrenia patients in nine Asian countries and territories were examined from 2001 to 2009. TD was evaluated as "present" or "absent" according to the clinical judgment of experienced psychiatrists. The patients' socio-demographic and clinical characteristics and the prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results: The frequency of TD in the whole sample was 5.0% with wide variations between countries (0-14.9%). Multiple logistic regression analysis showed that the following variables were independently associated with TD: study time, study site, older age, male gender, more severe negative and extrapyramidal symptoms and less anticholinergic drugs. Conclusions: A generally low frequency of TD in Asian schizophrenia patients with inter-ethnic variations was recorded. It is unclear whether the low prevalence of TD compared with Western data is real or the result of it being insufficiently recognized. ©2011 Dustri-Verlag Dr. K. Feistle.en_US
dc.languageengen_US
dc.publisherDustri-Verlag Dr. Karl Feistle. The Journal's web site is located at http://www.dustri.com/nc/journals-in-english/mag/int-journal-of-clinical-pharmacology-and-therapeutics.html-
dc.relation.ispartofInternational Journal of Clinical Pharmacology and Therapeuticsen_US
dc.subjectEthnicity-
dc.subjectSchizophrenia-
dc.subjectTardive dyskinesia-
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntipsychotic Agents - Adverse Effectsen_US
dc.subject.meshAsian Continental Ancestry Groupen_US
dc.subject.meshDyskinesia, Drug-Induced - Epidemiology - Ethnology - Etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshSchizophrenia - Complications - Drug Therapyen_US
dc.subject.meshTime Factorsen_US
dc.titleTardive dyskinesia in the treatment of schizophrenia: The findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)en_US
dc.typeArticleen_US
dc.identifier.emailLee, EHM:edwinlhm@hku.hken_US
dc.identifier.authorityLee, EHM=rp01575en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.5414/CP201505en_US
dc.identifier.pmid21612745-
dc.identifier.scopuseid_2-s2.0-79959466318en_US
dc.identifier.hkuros206323-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79959466318&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume49en_US
dc.identifier.issue6en_US
dc.identifier.spage382en_US
dc.identifier.epage387en_US
dc.identifier.isiWOS:000292222700005-
dc.publisher.placeGermany-
dc.identifier.scopusauthoridXiang, YT=35241398400en_US
dc.identifier.scopusauthoridWang, CY=7501646810en_US
dc.identifier.scopusauthoridSi, TM=6701400479en_US
dc.identifier.scopusauthoridLee, EHM=7406967099en_US
dc.identifier.scopusauthoridHe, YL=24780698400en_US
dc.identifier.scopusauthoridUngvari, GS=7006092063en_US
dc.identifier.scopusauthoridChiu, HFK=24447976700en_US
dc.identifier.scopusauthoridYang, SY=39561692200en_US
dc.identifier.scopusauthoridChong, MY=7102632108en_US
dc.identifier.scopusauthoridTan, CH=7402817882en_US
dc.identifier.scopusauthoridKua, EH=7006748699en_US
dc.identifier.scopusauthoridFujii, S=7401814463en_US
dc.identifier.scopusauthoridSim, K=8513485500en_US
dc.identifier.scopusauthoridYong, KH=37054832300en_US
dc.identifier.scopusauthoridTrivedi, JK=7005836490en_US
dc.identifier.scopusauthoridChung, EK=7202734618en_US
dc.identifier.scopusauthoridUdomratn, P=6602459819en_US
dc.identifier.scopusauthoridChee, KY=36100061600en_US
dc.identifier.scopusauthoridSartorius, N=7102159482en_US
dc.identifier.scopusauthoridShinfuku, N=7003855366en_US
dc.identifier.issnl0946-1965-

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