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Article: The effect of psychotherapy added to pharmacotherapy on cortisol responses in outpatients with major depressive disorder

TitleThe effect of psychotherapy added to pharmacotherapy on cortisol responses in outpatients with major depressive disorder
Authors
KeywordsAntidepressants
Awakening Cortisol Response
Body-Mind-Spirit Group Psychotherapy
Diurnal Saliva Cortisol
Major Depressive Disorder
Issue Date2009
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jonmd.com
Citation
Journal Of Nervous And Mental Disease, 2009, v. 197 n. 6, p. 401-406 How to Cite?
AbstractThe present study examined the changes of depressive symptoms and salivary cortisol responses in 36 outpatients with major depression. These patients were randomly assigned to receive combination therapy (CT), consisting of antidepressants and body-mind-spirit group psychotherapy, or monotherapy (MT), consisting of antidepressants only. The results indicated that CT and MT had similar effects on reducing depressive symptoms. Nevertheless, the results revealed that cortisol levels at night appeared to have a greater reduction in CT than in MT, indicating a downward trend in CT but an upward trend in MT. Moreover, a steeper diurnal pattern of cortisol-a larger deviation in cortisol levels between 30 and 45 minutes postwaking and evening-was more likely associated with CT than MT. The findings suggest that CT produced a protective effect on outpatients with major depression, preventing the increased night salivary cortisol levels and the flatter diurnal cortisol pattern that tended to occur in MT. © 2009 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/172218
ISSN
2023 Impact Factor: 1.6
2023 SCImago Journal Rankings: 0.655
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYang, TTen_US
dc.contributor.authorHsiao, FHen_US
dc.contributor.authorWang, KCen_US
dc.contributor.authorNg, SMen_US
dc.contributor.authorHo, RTHen_US
dc.contributor.authorChan, CLWen_US
dc.contributor.authorLai, YMen_US
dc.contributor.authorChen, YTen_US
dc.date.accessioned2012-10-30T06:20:46Z-
dc.date.available2012-10-30T06:20:46Z-
dc.date.issued2009en_US
dc.identifier.citationJournal Of Nervous And Mental Disease, 2009, v. 197 n. 6, p. 401-406en_US
dc.identifier.issn0022-3018en_US
dc.identifier.urihttp://hdl.handle.net/10722/172218-
dc.description.abstractThe present study examined the changes of depressive symptoms and salivary cortisol responses in 36 outpatients with major depression. These patients were randomly assigned to receive combination therapy (CT), consisting of antidepressants and body-mind-spirit group psychotherapy, or monotherapy (MT), consisting of antidepressants only. The results indicated that CT and MT had similar effects on reducing depressive symptoms. Nevertheless, the results revealed that cortisol levels at night appeared to have a greater reduction in CT than in MT, indicating a downward trend in CT but an upward trend in MT. Moreover, a steeper diurnal pattern of cortisol-a larger deviation in cortisol levels between 30 and 45 minutes postwaking and evening-was more likely associated with CT than MT. The findings suggest that CT produced a protective effect on outpatients with major depression, preventing the increased night salivary cortisol levels and the flatter diurnal cortisol pattern that tended to occur in MT. © 2009 by Lippincott Williams & Wilkins.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jonmd.comen_US
dc.relation.ispartofJournal of Nervous and Mental Diseaseen_US
dc.subjectAntidepressantsen_US
dc.subjectAwakening Cortisol Responseen_US
dc.subjectBody-Mind-Spirit Group Psychotherapyen_US
dc.subjectDiurnal Saliva Cortisolen_US
dc.subjectMajor Depressive Disorderen_US
dc.titleThe effect of psychotherapy added to pharmacotherapy on cortisol responses in outpatients with major depressive disorderen_US
dc.typeArticleen_US
dc.identifier.emailNg, SM: ngsiuman@hku.hken_US
dc.identifier.emailHo, RTH: tinho@hku.hken_US
dc.identifier.emailChan, CLW: cecichan@hku.hken_US
dc.identifier.authorityNg, SM=rp00611en_US
dc.identifier.authorityHo, RTH=rp00497en_US
dc.identifier.authorityChan, CLW=rp00579en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/NMD.0b013e3181a61594en_US
dc.identifier.pmid19525739-
dc.identifier.scopuseid_2-s2.0-67649399079en_US
dc.identifier.hkuros159624-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67649399079&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume197en_US
dc.identifier.issue6en_US
dc.identifier.spage401en_US
dc.identifier.epage406en_US
dc.identifier.isiWOS:000266941800004-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridYang, TT=10241889500en_US
dc.identifier.scopusauthoridHsiao, FH=7006744649en_US
dc.identifier.scopusauthoridWang, KC=24598349100en_US
dc.identifier.scopusauthoridNg, SM=7403358478en_US
dc.identifier.scopusauthoridHo, RTH=8620896500en_US
dc.identifier.scopusauthoridChan, CLW=35274549700en_US
dc.identifier.scopusauthoridLai, YM=7401512146en_US
dc.identifier.scopusauthoridChen, YT=8929240400en_US
dc.identifier.issnl0022-3018-

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