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- Publisher Website: 10.1016/0360-3016(90)90014-B
- Scopus: eid_2-s2.0-0025162886
- PMID: 2211261
- WOS: WOS:A1990EE63800013
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Article: Nasopharyngeal carcinoma: Orderly neck node spread
Title | Nasopharyngeal carcinoma: Orderly neck node spread |
---|---|
Authors | |
Keywords | Nasopharyngeal carcinoma Neck node Orderly spread |
Issue Date | 1990 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ijrobp |
Citation | International Journal of Radiation Oncology - Biology - Physics, 1990, v. 19 n. 4, p. 929-933 How to Cite? |
Abstract | A prospective study of 271 consecutive patients with newly diagnosed nasopharyngeal carcinoma was undertaken to assess the pattern of cervical nodal involvement with reference to 10 cervical nodal groups and three levels of neck; 204 (75.3%) patients were found to have cervical lymphadenopathy at presentation. Fifty-four (26.5%) of these patients had right cervical lymphadenopathy, 70 (34.3%) had left cervical lymphadenopathy, and 80% (39.2%) had bilateral cervical lymphadenopathy. The occurrence of lymphadenopathy in the 10 cervical nodal groups and the mean sizes of nodes in these nodal groups were computed. The subdigastric and upper jugular group was involved in more than 95% of cases. The lower the position in the neck, the less frequently the nodal group was involved. The mean size of nodes was largest in the subdigastric and upper jugular region compared with the other groups. The nodes in the upper neck were generally larger than those in the lower neck. The lower two levels of neck were involved without involvement of the upper level of the ipsilateral neck in fewer than 4% of cases. The present study indicates that neck node involvement by nasopharyngeal carcinoma is by orderly spread down the neck, which explains the adverse prognostic significance of neck node involvement in the lower neck. The orderly involvement of the neck nodes suggests that prophylactic irradiation of the neck should be given at least one level beyond the clinical extent of disease, which for patients with no clinically palpable node would mean prophylactic irradiation of the upper neck. |
Persistent Identifier | http://hdl.handle.net/10722/172623 |
ISSN | 2023 Impact Factor: 6.4 2023 SCImago Journal Rankings: 1.992 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sham, JST | en_US |
dc.contributor.author | Choy, D | en_US |
dc.contributor.author | Wei, WI | en_US |
dc.date.accessioned | 2012-10-30T06:23:49Z | - |
dc.date.available | 2012-10-30T06:23:49Z | - |
dc.date.issued | 1990 | en_US |
dc.identifier.citation | International Journal of Radiation Oncology - Biology - Physics, 1990, v. 19 n. 4, p. 929-933 | en_US |
dc.identifier.issn | 0360-3016 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/172623 | - |
dc.description.abstract | A prospective study of 271 consecutive patients with newly diagnosed nasopharyngeal carcinoma was undertaken to assess the pattern of cervical nodal involvement with reference to 10 cervical nodal groups and three levels of neck; 204 (75.3%) patients were found to have cervical lymphadenopathy at presentation. Fifty-four (26.5%) of these patients had right cervical lymphadenopathy, 70 (34.3%) had left cervical lymphadenopathy, and 80% (39.2%) had bilateral cervical lymphadenopathy. The occurrence of lymphadenopathy in the 10 cervical nodal groups and the mean sizes of nodes in these nodal groups were computed. The subdigastric and upper jugular group was involved in more than 95% of cases. The lower the position in the neck, the less frequently the nodal group was involved. The mean size of nodes was largest in the subdigastric and upper jugular region compared with the other groups. The nodes in the upper neck were generally larger than those in the lower neck. The lower two levels of neck were involved without involvement of the upper level of the ipsilateral neck in fewer than 4% of cases. The present study indicates that neck node involvement by nasopharyngeal carcinoma is by orderly spread down the neck, which explains the adverse prognostic significance of neck node involvement in the lower neck. The orderly involvement of the neck nodes suggests that prophylactic irradiation of the neck should be given at least one level beyond the clinical extent of disease, which for patients with no clinically palpable node would mean prophylactic irradiation of the upper neck. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ijrobp | en_US |
dc.relation.ispartof | International Journal of Radiation Oncology - Biology - Physics | en_US |
dc.subject | Nasopharyngeal carcinoma | - |
dc.subject | Neck node | - |
dc.subject | Orderly spread | - |
dc.subject.mesh | Head And Neck Neoplasms - Epidemiology - Pathology - Secondary | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Lymph Nodes - Pathology | en_US |
dc.subject.mesh | Nasopharyngeal Neoplasms - Epidemiology - Pathology | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.title | Nasopharyngeal carcinoma: Orderly neck node spread | en_US |
dc.type | Article | en_US |
dc.identifier.email | Wei, WI: hrmswwi@hku.hk | en_US |
dc.identifier.authority | Wei, WI=rp00323 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0360-3016(90)90014-B | - |
dc.identifier.pmid | 2211261 | - |
dc.identifier.scopus | eid_2-s2.0-0025162886 | en_US |
dc.identifier.volume | 19 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 929 | en_US |
dc.identifier.epage | 933 | en_US |
dc.identifier.isi | WOS:A1990EE63800013 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Sham, JST=7101655565 | en_US |
dc.identifier.scopusauthorid | Choy, D=7102939127 | en_US |
dc.identifier.scopusauthorid | Wei, WI=7403321552 | en_US |
dc.identifier.issnl | 0360-3016 | - |