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- Publisher Website: 10.1016/j.ogrm.2011.10.004
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Article: An update on gestational trophoblastic disease
Title | An update on gestational trophoblastic disease |
---|---|
Authors | |
Keywords | Choriocarcinoma Gestational Trophoblastic Disease Gestational Trophoblastic Neoplasia Management Mole |
Issue Date | 2012 |
Citation | Obstetrics, Gynaecology And Reproductive Medicine, 2012, v. 22 n. 1, p. 7-14 How to Cite? |
Abstract | Gestational trophoblastic disease is a rare pregnancy-related disorder. It comprises of partial mole, complete mole, invasive and metastatic mole, choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. Novel immunohistochemical technologies have helped in the diagnosis of the disease and some of the genes may also serve as prognostic markers. Partial and complete moles can be treated by suction evacuation and most patients do not require further treatment. However, 10-20% of them may develop gestational trophoblastic neoplasia. The Gynecological Oncology Committee has adopted a staging system with incorporation of the modified World Health Organization scoring system. Low-risk disease is treated by single-agent chemotherapy while high-risk disease is treated by multi-agent chemotherapy. The overall cure rate is more than 90% and most patients can preserve fertility and anticipate normal pregnancy outcomes. Nevertheless, the disease can recur. Referral to a specialist centre is important to ensure proper monitoring and management. © 2011. |
Persistent Identifier | http://hdl.handle.net/10722/173370 |
ISSN | 2023 SCImago Journal Rankings: 0.160 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tse, KY | en_US |
dc.contributor.author | Chan, KKL | en_US |
dc.contributor.author | Tam, KF | en_US |
dc.contributor.author | Ngan, HYS | en_US |
dc.date.accessioned | 2012-10-30T06:29:40Z | - |
dc.date.available | 2012-10-30T06:29:40Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | Obstetrics, Gynaecology And Reproductive Medicine, 2012, v. 22 n. 1, p. 7-14 | en_US |
dc.identifier.issn | 1751-7214 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173370 | - |
dc.description.abstract | Gestational trophoblastic disease is a rare pregnancy-related disorder. It comprises of partial mole, complete mole, invasive and metastatic mole, choriocarcinoma, placental site trophoblastic tumour and epithelioid trophoblastic tumour. Novel immunohistochemical technologies have helped in the diagnosis of the disease and some of the genes may also serve as prognostic markers. Partial and complete moles can be treated by suction evacuation and most patients do not require further treatment. However, 10-20% of them may develop gestational trophoblastic neoplasia. The Gynecological Oncology Committee has adopted a staging system with incorporation of the modified World Health Organization scoring system. Low-risk disease is treated by single-agent chemotherapy while high-risk disease is treated by multi-agent chemotherapy. The overall cure rate is more than 90% and most patients can preserve fertility and anticipate normal pregnancy outcomes. Nevertheless, the disease can recur. Referral to a specialist centre is important to ensure proper monitoring and management. © 2011. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Obstetrics, Gynaecology and Reproductive Medicine | en_US |
dc.subject | Choriocarcinoma | en_US |
dc.subject | Gestational Trophoblastic Disease | en_US |
dc.subject | Gestational Trophoblastic Neoplasia | en_US |
dc.subject | Management | en_US |
dc.subject | Mole | en_US |
dc.title | An update on gestational trophoblastic disease | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, KKL:kklchan@hkucc.hku.hk | en_US |
dc.identifier.email | Ngan, HYS:hysngan@hkucc.hku.hk | en_US |
dc.identifier.authority | Chan, KKL=rp00499 | en_US |
dc.identifier.authority | Ngan, HYS=rp00346 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.ogrm.2011.10.004 | en_US |
dc.identifier.scopus | eid_2-s2.0-84855862384 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-84855862384&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 22 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 7 | en_US |
dc.identifier.epage | 14 | en_US |
dc.identifier.scopusauthorid | Tse, KY=8876026900 | en_US |
dc.identifier.scopusauthorid | Chan, KKL=8655666700 | en_US |
dc.identifier.scopusauthorid | Tam, KF=7201692816 | en_US |
dc.identifier.scopusauthorid | Ngan, HYS=34571944100 | en_US |
dc.identifier.issnl | 1751-7214 | - |