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Article: Glycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line

TitleGlycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell line
Authors
Lam, KKWPang, RTKLee, CLKoistinen, HSeppala, MHo, PCYeung, WSBChiu, PCN
KeywordsDifferentiation
Fusion
Glycodelin
Human trophoblast
Invasion
Issue Date2012
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/placenta
Citation
Placenta, 2012, v. 33 n. 9, p. 750-752 How to Cite?
DOI: http://dx.doi.org/10.1016/j.placenta.2012.06.001
AbstractCytotrophoblasts are the key trophoblast cells which differentiate into different trophoblast lineages. In this report, glycodelin-A action on fusion of a cytotrophoblast-like cell line (BeWo) was investigated. It significantly reduced the spontaneous fusion of BeWo cells. The treatment enhanced the invasion and extracellular-signal regulated kinases activation of BeWo cells. The mRNA expression of syncytialization markers, human chorionic gonadotrophin and glial cells missing homolog 1 were suppressed upon glycodelin-A treatment. The data suggest a possible function of glycodelin-A in mediating cytotrophoblast differentiation. Crown Copyright © 2012 Published by Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/173377
ISSN
0143-4004
2023 Impact Factor: 3.0
2023 SCImago Journal Rankings: 0.983
ISI Accession Number ID
WOS:000308896300014
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLam, KKWen_HK
dc.contributor.authorPang, RTKen_HK
dc.contributor.authorLee, CLen_HK
dc.contributor.authorKoistinen, Hen_HK
dc.contributor.authorSeppala, Men_HK
dc.contributor.authorHo, PCen_HK
dc.contributor.authorYeung, WSBen_HK
dc.contributor.authorChiu, PCNen_HK
dc.date.accessioned2012-10-30T06:29:49Z-
dc.date.available2012-10-30T06:29:49Z-
dc.date.issued2012en_HK
dc.identifier.citationPlacenta, 2012, v. 33 n. 9, p. 750-752en_HK
dc.identifier.issn0143-4004en_HK
dc.identifier.urihttp://hdl.handle.net/10722/173377-
dc.description.abstractCytotrophoblasts are the key trophoblast cells which differentiate into different trophoblast lineages. In this report, glycodelin-A action on fusion of a cytotrophoblast-like cell line (BeWo) was investigated. It significantly reduced the spontaneous fusion of BeWo cells. The treatment enhanced the invasion and extracellular-signal regulated kinases activation of BeWo cells. The mRNA expression of syncytialization markers, human chorionic gonadotrophin and glial cells missing homolog 1 were suppressed upon glycodelin-A treatment. The data suggest a possible function of glycodelin-A in mediating cytotrophoblast differentiation. Crown Copyright © 2012 Published by Elsevier Ltd. All rights reserved.en_HK
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/placentaen_HK
dc.relation.ispartofPlacentaen_HK
dc.subjectDifferentiationen_HK
dc.subjectFusionen_HK
dc.subjectGlycodelinen_HK
dc.subjectHuman trophoblasten_HK
dc.subjectInvasionen_HK
dc.titleGlycodelin-A modulates syncytialization of human BeWo choriocarcinoma cell lineen_HK
dc.typeArticleen_HK
dc.identifier.emailPang, RTK: rtkpang@hku.hken_HK
dc.identifier.emailHo, PC: pcho@hku.hken_HK
dc.identifier.emailChiu, PCN: pchiucn@hku.hken_HK
dc.identifier.authorityPang, RTK=rp01761en_HK
dc.identifier.authorityHo, PC=rp00325en_HK
dc.identifier.authorityChiu, PCN=rp00424en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.placenta.2012.06.001en_HK
dc.identifier.pmid22748851-
dc.identifier.scopuseid_2-s2.0-84865230615en_HK
dc.identifier.hkuros209697-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84865230615&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume33en_HK
dc.identifier.issue9en_HK
dc.identifier.spage750en_HK
dc.identifier.epage752en_HK
dc.identifier.isiWOS:000308896300014-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLam, KKW=25637362300en_HK
dc.identifier.scopusauthoridPang, RTK=7004376636en_HK
dc.identifier.scopusauthoridLee, CL=9277221100en_HK
dc.identifier.scopusauthoridKoistinen, H=7003612125en_HK
dc.identifier.scopusauthoridSeppala, M=35475165300en_HK
dc.identifier.scopusauthoridHo, PC=7402211440en_HK
dc.identifier.scopusauthoridYeung, WSB=55763794967en_HK
dc.identifier.scopusauthoridChiu, PCN=25959969200en_HK
dc.identifier.issnl0143-4004-

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