File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1016/S0025-6196(12)65383-X
- Scopus: eid_2-s2.0-0024815009
- PMID: 2512459
- WOS: WOS:A1989CF37100008
- Find via
Supplementary
- Citations:
- Appears in Collections:
Conference Paper: Intrarenal mechanisms that regulate sodium excretion in relationship to changes in blood pressure
Title | Intrarenal mechanisms that regulate sodium excretion in relationship to changes in blood pressure |
---|---|
Authors | |
Issue Date | 1989 |
Publisher | Dowden Health Media, Inc. The Journal's web site is located at http://www.mayoclinicproceedings.com |
Citation | Mayo Clinic Proceedings, 1989, v. 64 n. 11, p. 1406-1424 How to Cite? |
Abstract | Because pressure-related natriuresis may be central to the regulatory role of the kidney on blood pressure, it is important to understand the relationship of humoral systems involved in the control of renal hemodyanmics and tubular function. The preglomerular endothelial synthesis of prostaglandin I2 and endothelium-derived relaxing factor seem to modulate autoregulatory control by the afferent arterioles and the release of renin by the juxtaglomerular apparatus. The release of renin is followed by an increase in angiotensin II in the renal interstitium, which is responsible for adjusting the vascular tone of the efferent arterioles and vasa recta and for stimulating proximal tubular reabsorption of sodium. Variations in medullary production of prostaglandins E2 and I2 and, ultimately, could modulate sodium reabsorption in the medullary thick ascending limbs and the collecting ducts. |
Persistent Identifier | http://hdl.handle.net/10722/173461 |
ISSN | 2023 Impact Factor: 6.9 2023 SCImago Journal Rankings: 1.783 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Romero, JC | en_US |
dc.contributor.author | Bentley, MD | en_US |
dc.contributor.author | Vanhoutte, PM | en_US |
dc.contributor.author | Knox, FG | en_US |
dc.date.accessioned | 2012-10-30T06:32:11Z | - |
dc.date.available | 2012-10-30T06:32:11Z | - |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Mayo Clinic Proceedings, 1989, v. 64 n. 11, p. 1406-1424 | en_US |
dc.identifier.issn | 0025-6196 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173461 | - |
dc.description.abstract | Because pressure-related natriuresis may be central to the regulatory role of the kidney on blood pressure, it is important to understand the relationship of humoral systems involved in the control of renal hemodyanmics and tubular function. The preglomerular endothelial synthesis of prostaglandin I2 and endothelium-derived relaxing factor seem to modulate autoregulatory control by the afferent arterioles and the release of renin by the juxtaglomerular apparatus. The release of renin is followed by an increase in angiotensin II in the renal interstitium, which is responsible for adjusting the vascular tone of the efferent arterioles and vasa recta and for stimulating proximal tubular reabsorption of sodium. Variations in medullary production of prostaglandins E2 and I2 and, ultimately, could modulate sodium reabsorption in the medullary thick ascending limbs and the collecting ducts. | en_US |
dc.language | eng | en_US |
dc.publisher | Dowden Health Media, Inc. The Journal's web site is located at http://www.mayoclinicproceedings.com | en_US |
dc.relation.ispartof | Mayo Clinic Proceedings | en_US |
dc.subject.mesh | Blood Pressure | en_US |
dc.subject.mesh | Epoprostenol - Biosynthesis | en_US |
dc.subject.mesh | Homeostasis | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hypertension - Etiology | en_US |
dc.subject.mesh | Kidney - Physiology | en_US |
dc.subject.mesh | Natriuresis - Physiology | en_US |
dc.subject.mesh | Nitric Oxide - Secretion | en_US |
dc.subject.mesh | Sodium, Dietary - Metabolism | en_US |
dc.title | Intrarenal mechanisms that regulate sodium excretion in relationship to changes in blood pressure | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/S0025-6196(12)65383-X | - |
dc.identifier.pmid | 2512459 | - |
dc.identifier.scopus | eid_2-s2.0-0024815009 | en_US |
dc.identifier.volume | 64 | en_US |
dc.identifier.issue | 11 | en_US |
dc.identifier.spage | 1406 | en_US |
dc.identifier.epage | 1424 | en_US |
dc.identifier.isi | WOS:A1989CF37100008 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Romero, JC=7402018868 | en_US |
dc.identifier.scopusauthorid | Bentley, MD=7101787937 | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.scopusauthorid | Knox, FG=7102239703 | en_US |
dc.identifier.issnl | 0025-6196 | - |