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undergraduate thesis: Distortion product otoacoustic emissions in patients with haemophilia
Title | Distortion product otoacoustic emissions in patients with haemophilia |
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Authors | |
Issue Date | 2010 |
Publisher | The University of Hong Kong (Pokfulam, Hong Kong) |
Citation | Leung, H. [梁曦田]. (2010). Distortion product otoacoustic emissions in patients with haemophilia. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. |
Abstract | This study investigated the cochlear function of 13 haemophilic patients using distortion product
otoacoustic emission (DPOAE) assessment techniques. Out of the 26 ears examined, a minority
of them produced responses that were considered to be impaired. A positive correlation was
found between clotting factor level and DPOAE amplitude, and DPOAE/ noise ratio at high
frequencies (4, 6, 8 kHz). Clotting factor level, which is indicative of the severity of
haemophilia, may be related to hearing status. It was also revealed that DPOAE amplitude and
DPOAE/ noise ratio at low frequencies (1, 2, 3 kHz) were greater than those at high frequencies
(4, 6, 8 kHz). Therefore the high-frequency cochlear region may be more sensitive to damage.
Intracranial micro-haemorrhage in haemophilic individuals may be linked to an increased risk of
cochlear damage. Further studies may use brain computed tomography scan to explore the
possible link between intracranial micro-haemorrhage and hearing loss. |
Description | "A dissertation submitted in partial fulfillment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, June 30, 2010." Includes bibliographical references (p. 22-24). Thesis (B.Sc)--University of Hong Kong, 2010. |
Degree | Bachelor of Science in Speech and Hearing Sciences |
Subject | Otoacoustic emissions. Hemophiliacs. |
Dept/Program | Speech and Hearing Sciences |
Persistent Identifier | http://hdl.handle.net/10722/173719 |
HKU Library Item ID | b4813170 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leung, Hei-tin | en_HK |
dc.contributor.author | 梁曦田 | zh_HK |
dc.date.accessioned | 2012-11-01T01:14:08Z | - |
dc.date.available | 2012-11-01T01:14:08Z | - |
dc.date.issued | 2010 | en_US |
dc.identifier.citation | Leung, H. [梁曦田]. (2010). Distortion product otoacoustic emissions in patients with haemophilia. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. | - |
dc.identifier.uri | http://hdl.handle.net/10722/173719 | - |
dc.description | "A dissertation submitted in partial fulfillment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, June 30, 2010." | en_US |
dc.description | Includes bibliographical references (p. 22-24). | en_US |
dc.description | Thesis (B.Sc)--University of Hong Kong, 2010. | en_US |
dc.description.abstract | This study investigated the cochlear function of 13 haemophilic patients using distortion product otoacoustic emission (DPOAE) assessment techniques. Out of the 26 ears examined, a minority of them produced responses that were considered to be impaired. A positive correlation was found between clotting factor level and DPOAE amplitude, and DPOAE/ noise ratio at high frequencies (4, 6, 8 kHz). Clotting factor level, which is indicative of the severity of haemophilia, may be related to hearing status. It was also revealed that DPOAE amplitude and DPOAE/ noise ratio at low frequencies (1, 2, 3 kHz) were greater than those at high frequencies (4, 6, 8 kHz). Therefore the high-frequency cochlear region may be more sensitive to damage. Intracranial micro-haemorrhage in haemophilic individuals may be linked to an increased risk of cochlear damage. Further studies may use brain computed tomography scan to explore the possible link between intracranial micro-haemorrhage and hearing loss. | en_US |
dc.language | eng | en_US |
dc.publisher | The University of Hong Kong (Pokfulam, Hong Kong) | en_US |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | en_US |
dc.rights | The author retains all proprietary rights, (such as patent rights) and the right to use in future works. | en_US |
dc.subject.lcsh | Otoacoustic emissions. | en_US |
dc.subject.lcsh | Hemophiliacs. | en_US |
dc.title | Distortion product otoacoustic emissions in patients with haemophilia | en_HK |
dc.type | UG_Thesis | en_US |
dc.identifier.hkul | b4813170 | en_US |
dc.description.thesisname | Bachelor of Science in Speech and Hearing Sciences | en_US |
dc.description.thesislevel | Bachelor | en_US |
dc.description.thesisdiscipline | Speech and Hearing Sciences | en_US |
dc.description.nature | published_or_final_version | en_US |
dc.identifier.mmsid | 991033679859703414 | - |