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- Publisher Website: 10.1111/j.1445-5994.1980.tb04095.x
- Scopus: eid_2-s2.0-0018953554
- PMID: 7000061
- WOS: WOS:A1980KE26900008
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Article: Effects of cimetidine on the healing of benign gastric ulcers
Title | Effects of cimetidine on the healing of benign gastric ulcers |
---|---|
Authors | |
Issue Date | 1980 |
Publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/IMJ |
Citation | Australian And New Zealand Journal Of Medicine, 1980, v. 10 n. 4, p. 430-432 How to Cite? |
Abstract | A prospective double-blind trial was undertaken to determine whether treatment with cimetidine influenced the healing of gastric ulcers in New Zealand patients. Ulcer size and healing was assessed by endoscopic examination. Of the 30 patients who completed the trial, 15 were given cimetidine and 15 placebo. At six weeks, 60% of the patients on cimetidine had healed their ulcers, whereas only 20% of those on the placebo had healed ulcers (P<0.05). Fewer patients taking cimetidine required antacids for symptom control than those on placebo treatment (P<0.05). The study confirmed that cimetidine treatment accelerates the healing of gastric ulcers. Histamine H 2 receptor antagonists have become an accepted treatment for both gastric and duodenal ulceration. In order to confirm that cimetidine is effective in the treatment of gastric ulcer in New Zealand patients, a double-blind study was carried out on outpatients with uncomplicated gastric ulcers. |
Persistent Identifier | http://hdl.handle.net/10722/175614 |
ISSN | |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Clarke, AC | en_US |
dc.contributor.author | Lee, SP | en_US |
dc.contributor.author | TasmanJones, C | en_US |
dc.date.accessioned | 2012-11-26T09:00:08Z | - |
dc.date.available | 2012-11-26T09:00:08Z | - |
dc.date.issued | 1980 | en_US |
dc.identifier.citation | Australian And New Zealand Journal Of Medicine, 1980, v. 10 n. 4, p. 430-432 | en_US |
dc.identifier.issn | 0004-8291 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/175614 | - |
dc.description.abstract | A prospective double-blind trial was undertaken to determine whether treatment with cimetidine influenced the healing of gastric ulcers in New Zealand patients. Ulcer size and healing was assessed by endoscopic examination. Of the 30 patients who completed the trial, 15 were given cimetidine and 15 placebo. At six weeks, 60% of the patients on cimetidine had healed their ulcers, whereas only 20% of those on the placebo had healed ulcers (P<0.05). Fewer patients taking cimetidine required antacids for symptom control than those on placebo treatment (P<0.05). The study confirmed that cimetidine treatment accelerates the healing of gastric ulcers. Histamine H 2 receptor antagonists have become an accepted treatment for both gastric and duodenal ulceration. In order to confirm that cimetidine is effective in the treatment of gastric ulcer in New Zealand patients, a double-blind study was carried out on outpatients with uncomplicated gastric ulcers. | en_US |
dc.language | eng | en_US |
dc.publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/IMJ | en_US |
dc.relation.ispartof | Australian and New Zealand Journal of Medicine | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Antacids - Therapeutic Use | en_US |
dc.subject.mesh | Cimetidine - Adverse Effects - Pharmacology - Therapeutic Use | en_US |
dc.subject.mesh | Clinical Trials As Topic | en_US |
dc.subject.mesh | Double-Blind Method | en_US |
dc.subject.mesh | Endoscopy | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Gastroscopy | en_US |
dc.subject.mesh | Guanidines - Therapeutic Use | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.subject.mesh | Stomach Ulcer - Drug Therapy | en_US |
dc.subject.mesh | Wound Healing - Drug Effects | en_US |
dc.title | Effects of cimetidine on the healing of benign gastric ulcers | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lee, SP: sumlee@hku.hk | en_US |
dc.identifier.authority | Lee, SP=rp01351 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1111/j.1445-5994.1980.tb04095.x | - |
dc.identifier.pmid | 7000061 | - |
dc.identifier.scopus | eid_2-s2.0-0018953554 | en_US |
dc.identifier.volume | 10 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 430 | en_US |
dc.identifier.epage | 432 | en_US |
dc.identifier.isi | WOS:A1980KE26900008 | - |
dc.publisher.place | Australia | en_US |
dc.identifier.scopusauthorid | Clarke, AC=7403682654 | en_US |
dc.identifier.scopusauthorid | Lee, SP=7601417497 | en_US |
dc.identifier.scopusauthorid | TasmanJones, C=7003303326 | en_US |
dc.identifier.issnl | 0004-8291 | - |