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Article: Familiality of clinical characteristics in schizophrenia

TitleFamiliality of clinical characteristics in schizophrenia
Authors
KeywordsClinical characteristics
Genetics
Schizophrenia
Issue Date2002
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/jpsychires
Citation
Journal Of Psychiatric Research, 2002, v. 36 n. 5, p. 325-329 How to Cite?
AbstractFew studies have assessed the familiality of clinical characteristics in schizophrenia. Therefore, we set out to investigate the familiality of the following characteristics; age of onset, course of disorder, employment status at onset, impairment during disorder, marital status at onset, mode of onset and premorbid functioning. Clinical characteristics were recorded using the Operational Criteria Checklist for Psychotic Illness for 155 subjects with an RDC diagnosis of schizophrenia, schizoaffective disorder, or psychosis of unknown origin, from 61 families multiply affected by schizophrenia. Age of onset, course of disorder, impairment during disorder, mode of onset, and premorbid functioning were shown to be familial. The familiality of these clinical characteristics supports their use in the delineation of homogeneous subsets for future genetic studies. Copyright © 2002 Elsevier Science Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/175855
ISSN
2023 Impact Factor: 3.7
2023 SCImago Journal Rankings: 1.553
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWickham, Hen_US
dc.contributor.authorWalsh, Cen_US
dc.contributor.authorAsherson, Pen_US
dc.contributor.authorGill, Men_US
dc.contributor.authorOwen, MJen_US
dc.contributor.authorMcguffin, Pen_US
dc.contributor.authorMurray, Ren_US
dc.contributor.authorSham, Pen_US
dc.date.accessioned2012-11-26T09:01:50Z-
dc.date.available2012-11-26T09:01:50Z-
dc.date.issued2002en_US
dc.identifier.citationJournal Of Psychiatric Research, 2002, v. 36 n. 5, p. 325-329en_US
dc.identifier.issn0022-3956en_US
dc.identifier.urihttp://hdl.handle.net/10722/175855-
dc.description.abstractFew studies have assessed the familiality of clinical characteristics in schizophrenia. Therefore, we set out to investigate the familiality of the following characteristics; age of onset, course of disorder, employment status at onset, impairment during disorder, marital status at onset, mode of onset and premorbid functioning. Clinical characteristics were recorded using the Operational Criteria Checklist for Psychotic Illness for 155 subjects with an RDC diagnosis of schizophrenia, schizoaffective disorder, or psychosis of unknown origin, from 61 families multiply affected by schizophrenia. Age of onset, course of disorder, impairment during disorder, mode of onset, and premorbid functioning were shown to be familial. The familiality of these clinical characteristics supports their use in the delineation of homogeneous subsets for future genetic studies. Copyright © 2002 Elsevier Science Ltd.en_US
dc.languageengen_US
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/jpsychiresen_US
dc.relation.ispartofJournal of Psychiatric Researchen_US
dc.subjectClinical characteristics-
dc.subjectGenetics-
dc.subjectSchizophrenia-
dc.subject.meshAdulten_US
dc.subject.meshAge Of Onseten_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshRandom Allocationen_US
dc.subject.meshSchizophrenia - Diagnosis - Epidemiology - Geneticsen_US
dc.subject.meshSeverity Of Illness Indexen_US
dc.titleFamiliality of clinical characteristics in schizophreniaen_US
dc.typeArticleen_US
dc.identifier.emailSham, P: pcsham@hku.hken_US
dc.identifier.authoritySham, P=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0022-3956(02)00008-0en_US
dc.identifier.pmid12127600-
dc.identifier.scopuseid_2-s2.0-0036019988en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036019988&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume36en_US
dc.identifier.issue5en_US
dc.identifier.spage325en_US
dc.identifier.epage329en_US
dc.identifier.isiWOS:000178254700007-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridWickham, H=6701762103en_US
dc.identifier.scopusauthoridWalsh, C=7401952516en_US
dc.identifier.scopusauthoridAsherson, P=35402700900en_US
dc.identifier.scopusauthoridGill, M=35228962600en_US
dc.identifier.scopusauthoridOwen, MJ=36044041500en_US
dc.identifier.scopusauthoridMcGuffin, P=22954119700en_US
dc.identifier.scopusauthoridMurray, R=35406239400en_US
dc.identifier.scopusauthoridSham, P=34573429300en_US
dc.identifier.issnl0022-3956-

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