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Article: Effect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma patients

TitleEffect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma patients
Authors
KeywordsAcute angle closure
Central corneal endothelial cell density
Primary angle closure glaucoma
Specular microscopy
Issue Date2006
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.com
Citation
Journal Of Glaucoma, 2006, v. 15 n. 6, p. 482-485 How to Cite?
AbstractPURPOSE: To document the effect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma (CACG) patients. METHODS: Consecutive cases of CACG with patent peripheral iridotomy had their central corneal endothelial cell density measured by specular microscopy. The corneal endothelial cell density of those CACG eyes with a previous documented acute angle closure attack were compared with those eyes without such a history, to determine the effect of a previous acute angle closure attack on corneal endothelial cell density. RESULTS: From July 2003 to July 2005, a total of 52 CACG eyes of 52 patients fulfilling the study criteria were recruited. Thirteen eyes (25%) had a previous documented acute angle closure attack, whereas 39 eyes (75%) did not. The mean central corneal endothelial cell density ±1 standard deviation was 2271.7±312.9 (range, 1556 to 2661) cells/mm in those CACG eyes with previous acute angle closure, and 2570.0±429.9 (range, 1669 to 3861) cells/mm in those CACG eyes without previous acute angle closure (P<0.05, Student t test). A previous acute angle closure attack in a CACG eye correlates with a 11.6% reduction in corneal endothelial cell density, compared with a CACG eye without such a history. There were no statistically significant differences between the 2 groups in age, LogMAR visual acuity, intraocular pressure, number of glaucoma eye drops, vertical cup-to-disk ratio, mean deviation or pattern standard deviation in Humphrey automated perimetry (P>0.05). CONCLUSIONS: A previous acute angle closure attack correlates with a significantly reduced corneal endothelial cell density in CACG patients. © 2006 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/176459
ISSN
2023 Impact Factor: 2.0
2023 SCImago Journal Rankings: 0.995
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTham, CCYen_US
dc.contributor.authorKwong, YYYen_US
dc.contributor.authorLai, JSMen_US
dc.contributor.authorLam, DSCen_US
dc.date.accessioned2012-11-26T09:11:36Z-
dc.date.available2012-11-26T09:11:36Z-
dc.date.issued2006en_US
dc.identifier.citationJournal Of Glaucoma, 2006, v. 15 n. 6, p. 482-485en_US
dc.identifier.issn1057-0829en_US
dc.identifier.urihttp://hdl.handle.net/10722/176459-
dc.description.abstractPURPOSE: To document the effect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma (CACG) patients. METHODS: Consecutive cases of CACG with patent peripheral iridotomy had their central corneal endothelial cell density measured by specular microscopy. The corneal endothelial cell density of those CACG eyes with a previous documented acute angle closure attack were compared with those eyes without such a history, to determine the effect of a previous acute angle closure attack on corneal endothelial cell density. RESULTS: From July 2003 to July 2005, a total of 52 CACG eyes of 52 patients fulfilling the study criteria were recruited. Thirteen eyes (25%) had a previous documented acute angle closure attack, whereas 39 eyes (75%) did not. The mean central corneal endothelial cell density ±1 standard deviation was 2271.7±312.9 (range, 1556 to 2661) cells/mm in those CACG eyes with previous acute angle closure, and 2570.0±429.9 (range, 1669 to 3861) cells/mm in those CACG eyes without previous acute angle closure (P<0.05, Student t test). A previous acute angle closure attack in a CACG eye correlates with a 11.6% reduction in corneal endothelial cell density, compared with a CACG eye without such a history. There were no statistically significant differences between the 2 groups in age, LogMAR visual acuity, intraocular pressure, number of glaucoma eye drops, vertical cup-to-disk ratio, mean deviation or pattern standard deviation in Humphrey automated perimetry (P>0.05). CONCLUSIONS: A previous acute angle closure attack correlates with a significantly reduced corneal endothelial cell density in CACG patients. © 2006 Lippincott Williams & Wilkins, Inc.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.comen_US
dc.relation.ispartofJournal of Glaucomaen_US
dc.subjectAcute angle closure-
dc.subjectCentral corneal endothelial cell density-
dc.subjectPrimary angle closure glaucoma-
dc.subjectSpecular microscopy-
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCell Counten_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshEndothelium, Corneal - Pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Angle-Closure - Physiopathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressureen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshVisual Acuityen_US
dc.titleEffect of a previous acute angle closure attack on the corneal endothelial cell density in chronic angle closure glaucoma patientsen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/01.ijg.0000212273.73100.31en_US
dc.identifier.pmid17106359-
dc.identifier.scopuseid_2-s2.0-33751032158en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33751032158&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume15en_US
dc.identifier.issue6en_US
dc.identifier.spage482en_US
dc.identifier.epage485en_US
dc.identifier.isiWOS:000242264200002-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridKwong, YYY=8614665700en_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US
dc.identifier.issnl1057-0829-

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